Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.
He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.
onlinelibrary.wiley.com/doi/10.1002/...
#ChemSky #ChemBio #Covalent #CovalentInhibitor
Very happy that @marnixroseboom.bsky.social represented our group of the @led3hub.bsky.social with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.
#ChemSky #ChemBio #ProudPI
A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me.
#CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio #ChemSky
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