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Figure 2 Minden (2026): Output of the effects of zebularine treatment at seed germination on plant traits showing transgenerational plasticity (i.e., with a significant PT effect or interaction PT × OT). Means and ± standard errors for plant traits and for each species separately. Parental generation was either grown under N-limitation or balanced nutrient supply, offspring generation either under N-limitation (left columns, orange and yellow graphs) or balanced nutrient supply (right columns, blue graphs). Orange bars and dark-blue bars show trait values for Control-zebularine treatments (0µM), yellow bars and light-blue bars for zebularine 50 µM. Asterisks indicate significance of parental nutrient treatment, for each zebularine treatment and parental/offspring treatment-combination separately (i.e. for bar graphs of the same colour) and done with Tukey test using marginal means, with *p < 0.05, **p < 0.01, ***p < 0.001 and n.s. at p > 0.05. Exact p-values for each trait are given in

Figure 2 Minden (2026): Output of the effects of zebularine treatment at seed germination on plant traits showing transgenerational plasticity (i.e., with a significant PT effect or interaction PT × OT). Means and ± standard errors for plant traits and for each species separately. Parental generation was either grown under N-limitation or balanced nutrient supply, offspring generation either under N-limitation (left columns, orange and yellow graphs) or balanced nutrient supply (right columns, blue graphs). Orange bars and dark-blue bars show trait values for Control-zebularine treatments (0µM), yellow bars and light-blue bars for zebularine 50 µM. Asterisks indicate significance of parental nutrient treatment, for each zebularine treatment and parental/offspring treatment-combination separately (i.e. for bar graphs of the same colour) and done with Tukey test using marginal means, with *p < 0.05, **p < 0.01, ***p < 0.001 and n.s. at p > 0.05. Exact p-values for each trait are given in

New publication: Effects of #DNAdemethylation on the #expression of plastic and transgenerational #responses to #nitrogen availability in annual #plant species, by @kjfverhoeven.bsky.social and other.
doi.org/10.1007/s106...

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This review highlights TET1, a key enzyme in #DNADemethylation, showing dual roles in #Cancer with both #Oncogenic and #Tumor suppressive properties, emphasizing the need for deeper mechanistic insights. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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Epigenetics Update - Preventing CpG hypermethylation in oocytes safeguards mouse development bit.ly/41u5adm

Antoine H.F.M. Peters (FMI/ University of Basel) reporting in Dev Cell

#Epigenetics #DNAme #DNAm #DNAdemethylation #Embryogenesis
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Discover the breakthrough at epigenometech.com

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Epigenetics Update - Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers
bit.ly/44H3zCZ

Robert K. McGinty (UNC Chapel Hill) reporting in Mol Cell

#Epigenetics #DNADemethylation #Chromatin
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Discover the breakthrough at epigenometech.com

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OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide - Nature Structural & Molecular Biology Here the authors show that the disruption of OGT expression in mouse embryonic stem cells unleashes TET activity, causing genome-wide decreases in DNA methylation and increases in 5-hydroxymethylcytos...

Epigenetics Update - OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide go.nature.com/4laK9MG

#Epigenetics #DNAdemethylation #mESCs
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Gain deeper insights into gene regulation; epigenometech.com

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