She's better off than your average Russian-born person, though she needs a bottle of #Disulfiram next to that bottle of $15/pop sparkling wine, & some schooling in taste. Just as #Trump, despite having a well-to-do life these fuckers are no connaisseurs of quality.
Here's your average Russian...
#Disulfiram #Atherosclerosis
Inducer of #Autophagy in Mφ/#EndothelialCell/#SmoothMuscleCell/#Hepatocyte, independent of GSDMD
Inhibitor of mouse #Atherosclerosis, likely independent of cholesterol level
+Altered #GutMicrobiota profile
#JAHA_AHA 2024
www.ahajournals.org/doi/10.1161/...
#Disulfiram, an FDA-approved anti-alcoholism drug, acts as an inhibitor for NLRP3 (but not poly(dA:dT)-AIM2, Salmonella-NLRC4) #Inflammasome
Disulfiram⏬ZDHHC5-mediated NLRP3 Cys126 Palmitoylation & subsequent trans-Golgi network localization in Mφ
#CellReports 2024
www.cell.com/cell-reports...
A key to restoring sight may be held in a drug that treats alcoholism www.urmc.rochester.edu/news/publications/neuros... "Treated mice really see better than mice without the drugs"; #disulfiram...
