Exposure to titanium and nickel as the novel risk factors for PCOS: Evidence from a case control study in Xiamen, China Polycystic ovary syndrome (PCOS) is a common cause of female infertility. While heavy metal exposure is a suspected risk factor, the role of trace ele…

#ecology #health #publichealth #gynecology #womenshealth #biomarkers #endocrinology #ecotoxicology #exposome #pathology

Elevated nickel (Ni)
and titanium (Ti)

are associated with
an increased risk of
PCOS.
.
www.sciencedirect.com/science/arti...

Serum and Hair Nickel Levels and Breast Cancer: Systematic Review and Meta-Analysis - Biological Trace Element Research Several studies have investigated the relationship between serum and hair nickel (Ni) concentration and breast cancer, but the results were inconsistent. Thus, we conducted a systematic review and meta-analysis to evaluate the association between serum and hair nickel levels and breast cancer. Nine studies determining the serum nickel levels and six studies evaluating the hair nickel levels were identified in a systematic search of PubMed, China Knowledge Resource Integrated Database, Wanfang, and China Biomedical Literature Service System databases. Based on a random-effects model, standard mean differences (SMD) and the corresponding 95% confidence intervals (CI) were pooled to compare the nickel levels between different groups. Compared with healthy controls, the serum nickel levels in breast cancer were significantly higher (SMD (95% CI) 1.76 (0.82, 2.70)), as well as in those post-treated cases (SMD (95% CI) 2.56 (1.18, 3.94)). For breast cancer cases, the treatment made no significant decrease in serum nickel levels (SMD (95% CI) −0.29 (−1.17, 0.59)). In hair, the nickel levels in breast cancer were slightly higher than in controls, but not significant (SMD (95% CI) 0.16 (−1.08, 1.40)). In conclusion, high serum nickel levels were associated with breast cancer, and nickel exposure might be a risk factor for breast cancer.

#health #ecology #agedcare #womenshealth #gerontology #biomarkers #primaryhealthcare #pathology #oncology #endocrinology #exposome #menopause #aging #ecotoxicology #SDGs

High blood levels of
metalloestrogens, such as
nickel (Ni)

are associated with
breast cancer
.
link.springer.com/article/10.1...

Temporal Variability and Predictors of Urinary Bisphenol A Concentrations in Men and Women Bisphenol A (BPA) is used to manufacture polymeric materials, such as polycarbonate plastics, and is found in a variety of consumer products. Recent data show widespread BPA exposure among the U.S. po...

#ecotoxicology #publichealth #health #exposome #analytical #chemistry #healthliteracy #SDGs #gerontology #IVF #fertility #ecology #pathology #NCDs

Shared sources of exposure
to bisphenol A (BPA)
in couples

result in
matching daily variations
in urinary BPA.
.
pmc.ncbi.nlm.nih.gov/articles/PMC...

Call for papers for Contaminants, Environment, and Society. Group of people collecting samples along a riverbank surrounded by trees for community contaminant research.

Researchers: CES seeks papers for its first ever collection on community action! Focus on studies led by or in partnership with communities addressing #chemical, #pollutant, and #toxin challenges.

More info ▶️ https://ow.ly/J56U50YffuJ

#ContaminantResearch #Toxicology #Ecotoxicology

Unraveling contaminant effects on biodiversity across scales: the macroecotoxicology perspective

In this new preprint, we call for the formal integration between #Macroecoloy & #Ecotoxicology by providing an operational framework & guidelines to achieve it. Take a look and spread the word!

Led my dear friend and colleague @gabrielmoulatlet.bsky.social

ecoevorxiv.org/repository/v...

Ocean acidification stimulates mass development of toxic algae 19. November 2018/Kiel. If carbon dioxide concentrations in the atmosphere and thereby in the ocean continue to rise, this could favour the mass development of toxic algae, with far-reaching consequen...

#sustainability #ecotoxicology

(Sources of CO2 emissions
need to be identified and addressed.)

The toxic alga Vicicitus globosus
strongly increases its abundance

at CO2 concentrations
above 600 ppm (parts per million)
and goes into mass development above 800 ppm.
.
www.geomar.de/en/news/arti...

An invasive predator may be the key to monitoring river pollution. 🦦
A CBMA study shows that the American mink reflects contaminants back into the environment, acting as an ecological sentinel.
🔗 Discover more: www.sciencedirect.com/science/arti...

#Ecotoxicology #CBMA

The Individual and Combined Effects of Warming and Atrazine on Lithobates pipiens Phenotypes: Implications for Frog Declines Amphibians are the most threatened vertebrate class globally. Climate change, agrochemicals, and/or pathogens and parasites are implicated in contributing to amphibian declines, either singly or in c...

Between contaminants and warming 🐸 This study shows how elevated temperature and atrazine interact in frogs (Lithobates pipiens), accelerating development but compromising immunity #Ecotoxicology #ClimateChange
onlinelibrary.wiley.com/doi/10.1002/...

#ecotoxicology

(Multigenerational exposure to
toxic metals
and other environmental pollutants
needs to be documented.)

Chronic pain/fatigue patients
were 14 times more likely to meet criteria for autism,
and 13 times more likely to meet criteria for ADHD
www.sciencedirect.com/science/arti...

Hidden risks associated with occupational pesticide exposure in women with breast cancer: High frequency of the Luminal B molecular subtype and occurrence of poor prognostic features Human pesticide exposure is a common event in countries with strength conventional agriculture, such as Brazil. Despite evidence on the negative impact of pesticides on human health, the country stand...

#ecology #health #publichealth #SDGs #oncology #ecotoxicology

Women in rural Brazil with
high pesticide exposure
were more likely to have

more aggressive breast cancer,
luminal B subtype,
cancer recurrence,
chemoresistance,
distant metastases,
lymph node invasion.
journals.plos.org/plosone/arti...

#sustainability #SDGs #health #ecotoxicology

Which preventive healthcare AI
is most effective in
reducing incidence rates of

breast cancer,
prostate cancer,
uterine cancer,
immune system disorders,
neurological disorders,
mental illness,
kidney disease,
liver disease?

#epidemiology #ecotoxicology #health #publichealth

Intra-tumoural manganese (Mn)
is associated with
reduced survival in
glioblastoma.

Mn contamination of food
is strongly associated with
soil Mn.

High soil Mn
is found in areas with
atmospheric deposition,
acidic (pH<5.5) and water-logged soil.
.

#health #oncology #ecotoxicology #womenshealth #publichealth

Benzophenone
promotes
breast cancer cell metastasis
via the Wnt/β-catenin pathway
.
www.sciencedirect.com/science/arti...

Life cycle benzophenone 1 exposure induces anxiety- and depression-like behaviors in zebrafish via endoplasmic reticulum stress-mediated dopaminergic system dysfunction Environmental exposure to benzophenones (BPs) has emerged as a potential risk factor for the comorbidity of anxiety and depression. Among them, BP1 ha…

#neurology #health #publichealth #mentalhealth #etiology #ecotoxicology

ER stress–mediated
dopaminergic disruption
underlies
benzophenone 1-induced
anxiety and depression
.
www.sciencedirect.com/science/arti...

Tissue-specific bioaccumulation and hepatotoxicity of 6PPD and 6PPD-Quinone in zebrafish Tire additive 6PPD and its transformation product 6PPD-Quinone have garnered substantial attention due to their association with mass salmon mortality…

#gerontology #ecotoxicology #biomarkers #publichealth #neurology #hepatology #forensic #pathology #health #oncology #aging #geriatrics #SDGs

Toxic chemicals released from tyres

6PPD accumulates in the liver and gut.
6PPD-Q accumulates in the liver and brain.
.
www.sciencedirect.com/science/arti...

#ecotoxicology #health

The 'parent hormone' pregnenolone
is significantly lower
in older adults,

increasing the risk of
cognitive decline,
pain,
and accelerated ageing.

P450scc is required to
convert cholesterol to pregnenolone.

This process is disrupted by
endocrine-disrupting chemicals.
.

#AI #ethics #sustainability #ecology #ecotoxicology #womenshealth #health #aging #gerontology #phthtalates #DEHP #SDGs

A lack of ethical guardrails in
preventive healthcare AI

results in harmful neglect of
human biomonitoring of priority pollutants
and identification of sources of exposure.

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways This research provides the first comprehensive evidence that PS-MPs exacerbate ccRCC progression by activating the NF-κB and TGF-β pathways. These findings establish PS-MPs as an environmental risk f....

#health #aging #publichealth #ecology #histology #pathology #gerontology #ecotoxicology #SDGs #oncology #exposome #toxicology

Polystyrene microplastics
aggravate
kidney cancer progression
.
advanced.onlinelibrary.wiley.com/doi/full/10....

Call for papers for Contaminants, Environment, and Society. Group of people collecting samples along a riverbank surrounded by trees for community contaminant research.

We are highlighting community-led #ContaminantResearch. The first ever collection on Community Action for Contaminant Research is now open for submissions.

Submit before 30 May, 2026 ▶️ https://ow.ly/CK1750Yfga2

#Contaminants #IndigenousKnowledge #MicroPlastics #Ecotoxicology

#health #sustainability #ecotoxicology

Current healthcare AI
is increasing
women's incidence rates (ASR) of

breast cancer,
uterine cancer,
kidney cancer,
autoimmune diseases, MS,
hypothyroidism,
depression,
and endometriosis,

instead of
monitoring risk factors
and reducing incidence rates.

#ecotoxicology #sustainability #SDGs

Ethical and sustainable healthcare AI
monitors bioaccumulation of

toxic metals,
persistent organic pollutants,
air pollutants,
and endocrine-disrupting chemicals

in the liver, kidneys, and other organs and tissues
and identifies sources of exposure.

#history #archaeology #medicine #ethics #epidemiology #ecotoxicology #MS #autoimmunity #autism #forensic #pathology #childhoodcancer #epigenetics #ecology #histology #publichealth #health #agedcare #SDGs

Patients'
parents'
and grandparents'

liver concentrations of pollutants
need to be documented.

#health #publichealth #ecology #ecotoxicology #womenshealth

Autoimmune diseases:

Exposure to environmental pollutants,
such as cadmium (Cd),
can lead to
the formation of anti-nuclear antibodies (IgG),
that attack healthy cells,
in susceptible individuals.
.
pmc.ncbi.nlm.nih.gov/articles/PMC...

Can cadmium toxicity be a driving force for iron deficiency anemia – a systematic review and meta-analysis Introduction There is a great deal of evidence that cadmium toxicity can have a significant impact on nutritional deficiencies, particularly iron deficiency. Therefore, in this study, we aimed to inve...

#health #ecology #publichealth #nutrition #foodsystems #gerontology #menopause #exposome #oncology #ecotoxicology #biomarkers #biomonitoring #SDGs #NCDs #womenshealth

Blood levels of
cadmium (Cd)
were significantly elevated in
cancer patients.
.
www.degruyterbrill.com/document/doi...

Cadmium Isotopes Reveal Dominant Atmospheric Deposition Pathways in Agroecosystems Atmospheric cadmium (Cd) deposition poses significant risks to agricultural ecosystems and food safety. However, quantitatively tracing the contribution and transport mechanisms of this Cd in soil–cro...

#health #ecology #publichealth #nutrition #SDGs #epidemiology #ecotoxicology #toxicology #dietetics #foodsystems

Toxic metals in food:

Isotope analysis shows that
foliar uptake of
atmospheric cadmium (Cd)
is a key pathway of cadmium accumulation in food crops.
.
pubs.acs.org/doi/abs/10.1...

Call for papers for Contaminants, Environment, and Society. Group of people collecting samples along a riverbank surrounded by trees for community contaminant research.

Our first ever collection invites research showing how communities, including Indigenous communities, lead contaminant research for health and policy impact.

Submit before 30 May, 2026 ▶️ https://ow.ly/nbtx50Yfg6l

#Contaminants #IndigenousKnowledge #MicroPlastics #Ecotoxicology

#epidemiology #ecotoxicology #healthinformatics #ecology #forensic #pathology #analytical #chemistry #SDGs

Which environmental pollutant mixtures
are found in liver biopsies
for each
- subtype of neurodegenerative disease,
- geographic region,
- birth year,
- genotype,
- and occupation?
.
.

#ecotoxicology

In Alzheimer's disease,
chronically activated GSK-3β kinase
(air pollution, certain toxic metals/elements)
causes tau to hyperphosphorylate
and detach from microtubules.

Chronically elevated cortisol and corticosteroids
cause elevated BACE1
and amyloid beta (Aβ) aggregation.
.

Multi‐omic expression of the VEGF family relates to Alzheimer's disease across diverse populations INTRODUCTION The vascular endothelial growth factor (VEGF) signaling family plays a role in neurodegenerative diseases, including Alzheimer's disease (AD). Previous work has shown widespread effects...

#ecotoxicology #health #geriatrics

(Elevated FLT1 and FLT4
are caused by
environmental pollutants,
such as PM2.5 and cadmium.)

Multi-omic expression of the VEGF family (FLT1, FLT4)
relates to
Alzheimer's disease
across diverse populations
alz-journals.onlinelibrary.wiley.com/doi/full/10....

Nitrogen Dioxide Inhalation Disrupts Bone Marrow Hematopoiesis by Inducing Stage-Specific Developmental Blockage in Erythroid and Granulocytic Lineages in Mice Nitrogen dioxide (NO2) exposure is a known risk factor for respiratory, cardiovascular, and neurological diseases and has also been linked to systemic hematological alterations, including an increased...

#publichealth #hematology #health #SDGs #ecotoxicology

Bone marrow
is particularly sensitive to
NO2 air pollution.

NO2 exposure triggered
anemia, with 10% decreases in RBC and hemoglobin.

Granulopoiesis was also altered,
with a 31% decrease in mature neutrophils.
.
pubs.acs.org/doi/full/10....