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Mapping pesticide mixtures to cancer risk at the country scale with spatial exposomics - Nature Health Using an integrative spatial Bayesian framework that merges high-resolution environmental pesticide risk modelling with comprehensive cancer registry data, this analysis reveals spatial patterns of pe...

From #Nature: "Mapping #pesticide mixtures to #cancer #risk at the country scale with #spatial #spatial #exposomics"

www.nature.com/articles/s44...

"... these findings strongly support a mechanistic link between pesticide exposure and cancer ..."

#Peru #Health #Polution #Environment

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Learn More:

The Phenome-Exposome Atlas:
🔗 pe.exposomeatlas.com

Harvard Medical School Press Release:
🔗 hms.harvard.edu/news/large-s...

#Exposomics #Exposome
@natureportfolio.nature.com

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How pollutants interact inside the body to impact health | Harvard T.H. Chan School of Public Health Peng Gao studies the “exposome”—the measure of an individual’s total environmental exposures over the course of their life and how those exposures impact biology and health.

Mapping the “exposome” to protect health.

@penggao.bsky.social, uses high-resolution mass spectrometry and multi-omics to reveal how pollutant mixtures shape asthma, cancer, Alzheimer’s risk, and more.

Read about the work. in the Gao Lab: hsph.me/hpiitbtih31026

#Exposomics #EnvHealth

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Panome Bio Introduces Innovative Exposomics Services to Advance Health Research Panome Bio has launched an exposomics platform, offering groundbreaking chemical exposure profiling services essential for disease research.

Panome Bio Introduces Innovative Exposomics Services to Advance Health Research #USA #St._Louis #Panome_Bio #Exposomics #Chemical_Exposure

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➡️Read the Full Spotlight:
🔗nexus-exposomics.org/news/walker_spotlight_Fe...

➡️Learn more about the ADSI Project:
🔗nexus-exposomics.org/news/ADSI_research_proje...
🔗dpcpsi.nih.gov/autism-data-science-init...

#exposomics #NEXUS

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Food, We Need To Talk In this episode, we talk with Dr. Gary Miller, a professor at Columbia University, about how the air we breathe, the water we drink, and the products we use every day may be shaping our health more th...

🎙️Food, We Need To Talk
The episode "It’s Not Your Genes. It Might Be Your Water." featuring NEXUS MPI Gary W. Miller is out now!

🔗Listen here: play.prx.org/listen?ge=pr...

#exposomics #exposome #NEXUS

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Two individuals in protective gear spraying pesticides across a field of crops. 
Image credit: Shutterstock/NataliAlba.

Two individuals in protective gear spraying pesticides across a field of crops. Image credit: Shutterstock/NataliAlba.

What if we could measure every #environmental exposure shaping our health? 🌍
Twenty years after its start, #Exposomics is ready to uncover the complex drivers of disease.

Read the PNAS News Feature: https://ow.ly/PBIM50Y4o4N

#PublicHealth #pollution #pesticides #wildfire

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New kit aims to quantify internal exposure in 7–10 days, offering a noninvasive way to track microplastic particle counts over time.

longevity.technology/news/lumati-...

#longevity #microplastics #exposomics #atHomeTesting #salivatest #environmentalhealth #preventivehealth #healthtracking

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Two individuals in protective gear spraying pesticides across a field of crops. 
Image credit: Shutterstock/NataliAlba.

Two individuals in protective gear spraying pesticides across a field of crops. Image credit: Shutterstock/NataliAlba.

What if we could measure the many #EnvironmentalExposures shaping our health? After 20 years, #exposomics is poised to reveal the interacting drivers of #disease. A PNAS News Feature: https://ow.ly/oxN750XY3sL

#PublicHealth #EnvironmentalHealthScience #pesticides #pollution

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Two individuals in protective gear spraying pesticides across a field of crops. 
Image credit: Shutterstock/NataliAlba.

Two individuals in protective gear spraying pesticides across a field of crops. Image credit: Shutterstock/NataliAlba.

Can we measure how countless #EnvironmentalExposures shape our health? After 20 years, #exposomics is poised to untangle how #pesticides, #pollution, #wildfires, and more interact to drive #disease. A PNAS News Feature: https://ow.ly/IbwG50XU6Jz

#biobank #genomics #PublicHealth

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Two individuals in protective gear spraying pesticides across a field of crops.
Image credit: Shutterstock/NataliAlba.

Two individuals in protective gear spraying pesticides across a field of crops. Image credit: Shutterstock/NataliAlba.

Twenty years on, #exposomics is revealing how #pesticides, #pollution, and #wildfires interact to drive #disease. Read the PNAS News Feature: https://ow.ly/JRJL50XR9xq

#biobank #genomics #PublicHealth #EnvironmentalHealthScience

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Two individuals in protective gear spraying pesticides across a field of crops
Image credit: Shutterstock/NataliAlba.

Two individuals in protective gear spraying pesticides across a field of crops Image credit: Shutterstock/NataliAlba.

#Exposome research comes of age: After 20 years, the field of #exposomics is poised to reveal the complex, interacting drivers of #disease. A PNAS News Feature: https://ow.ly/9QOg50XPn5J

#exposure #pesticides #pollution #wildfires #biobank #genomics #PublicHealth

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Scientists Thought Parkinson’s Was in Our Genes. It Might Be in the Water New ideas about chronic illness could revolutionize treatment, if we take the research seriously.

Rising Parkinson’s rates may have less to do with our genes and more with what’s in our water and air. New research ties chemicals like TCE to higher Parkinson’s risk and fuels a broader push to map lifetime environmental exposures. Read more: www.wired.com/story/scient... #Parkinsons #Exposomics

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MassBank

This celebrates 20 years since #MassBank started in Japan. The new system developed at @ipbhalle.bsky.social went live in June at both massbank.eu and massbank.jp. We had >20 releases of reference spectra submitted by not only the #metabolomics, #exposomics and #EnvironmentalScience communities.

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An estimated 90% of diseases have environmental triggers. These researchers want to build a framework for prevention Research into the exposome, a counterpart to the genome, gains momentum.

Imagine if the story of your health wasn’t written only in your DNA — but also in the air you breathe, the food you eat, and the stress you carry. That’s #exposomics: an emerging field mapping the full tapestry of life’s interactions.

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Human and Environmental Health Topic: Next Generation Risk Assessment In this episode, Aimee Altemus and Adelaide Frimpong speak with Dr. Gary Miller of Columbia University, a widely recognized leader in exposome research. Dr. Mil

🎙️ #AmericanCollegeofToxicology (ACT) ToxChats Podcast

The episode "Human and Environmental Health Topic: Next Generation Risk Assessment" featuring NEXUS MPI, Gary W. Miller is out now!

🔗Listen here: spreaker.com/episode/huma...

#exposomics
@exposome.bsky.social @exposomics.bsky.social

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The first session will focus on endocrine disruptors and examine opportunities/challenges in combining #SingleCell mapping and #Exposomics to advance the Human Exposome Project and human health in general. #Exposome #HumanCellAtlas

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Graphic with a photo of a woman looking at a band-aid on her arm, presumably just vaccinated. It includes the following quote from Chee Wah Tan, PhD, of the National University of Singapore, which was featured in the linked October 10, 2025 article in Genetic Engineering & Biotechnology News: “The human organoid system is particularly important in infectious disease research. Beyond serving as a physiologically relevant model to study viral pathogenesis, it has recently been applied to recapitulate key germinal center features in vitro, enabling the evaluation of humoral immune responses to vaccines without reliance on animal models—which are often poorly predictive of human vaccine responses.”

Graphic with a photo of a woman looking at a band-aid on her arm, presumably just vaccinated. It includes the following quote from Chee Wah Tan, PhD, of the National University of Singapore, which was featured in the linked October 10, 2025 article in Genetic Engineering & Biotechnology News: “The human organoid system is particularly important in infectious disease research. Beyond serving as a physiologically relevant model to study viral pathogenesis, it has recently been applied to recapitulate key germinal center features in vitro, enabling the evaluation of humoral immune responses to vaccines without reliance on animal models—which are often poorly predictive of human vaccine responses.”

#Organoid technology, coupled with AI, is advancing #exposomics & #immunology research

Featuring research from:
@stanfordmedicine.bsky.social
@gatechengineers.bsky.social
@mpi-nat.bsky.social
& more

www.genengnews.com/topics/trans...

#immunosky 🧪

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We’re accepting original research, reviews, and more on topics like:
📱 Sensors & wearables
🌿 Cumulative exposures
🧬 Exposome + genome

Submit your research by Aug 31, 2026 → buff.ly/Kekv2wu
#Exposomics #CallForPapers #FASEBJournal

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Inspiring lecture by Dragana Vuckovic in causal mediation analysis applied to #multiomics and #exposomics

profiles.imperial.ac.uk/d.vuckovic

#SISMEC2025

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Great final session of the #BMD2025 in #Leiden Universiteit Leiden today! 😎 With our own @mmzdouc.bsky.social presenting #FERMO, including a flashback to his talk 3 years ago in Utrecht at the #BMD2022, and a fantastic keynote by Jonathan Martin on the #metabolomics of #exposomics!

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Interested in a co-authorship?
We’re building a tool for repository-scale untargeted #metabolomics and #exposomics of #environmental data. To make it the best it can be, we’re looking for people willing to share high-resolution LC-MS/MS (DDA) data from #water, #soil, #sediment, and related samples.

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A Perspective on Unintentional Fragments and their Impact on the Dark Metabolome, Untargeted Profiling, Molecular Networking, Public Data, and Repository Scale Analysis. In/post-source fragments (ISFs) arise during electrospray ionization or ion transfer in mass spectrometry when molecular bonds break, generating ions that can complicate data interpretation. Although ISFs have been recognized for decades, their contribution to untargeted metabolomics - particularly in the context of the so-called “dark matter” (unannotated MS or MS/MS spectra) and the “dark metabolome” (unannotated molecules) - remains unsettled. This ongoing debate reflects a central tension: while some caution against overinterpreting unidentified signals lacking biological evidence, others argue that dismissing them too quickly risks overlooking genuine molecular discoveries. These discussions also raise a deeper question: what exactly should be considered part of the metabolome? As metabolomics advances toward large-scale data mining and high-throughput computational analysis, resolving these conceptual and methodological ambiguities has become essential. In this perspective, we propose a refined definition of the “dark metabolome” and present a systematic overview of ISFs and related ion forms, including adducts and multimers. We examine their impact on metabolite annotation, experimental design, statistical analysis, computational workflows, and repository-scale data mining. Finally, we provide practical recommendations - including a set of dos and don’ts for researchers and reviewers - and discuss the broader implications of ISFs for how the field explores unknown molecular space. By embracing a more nuanced understanding of ISFs, metabolomics can achieve greater rigor, reduce misinterpretation, and unlock new opportunities for discovery.

If you’ve been following #metabolomics literature, you’ve probably seen a lot of debate on in-source fragmentation. We’ve put together a manuscript to clarify what it is, how to deal with it, and what it means for discovery in #metabolomics and #exposomics.
doi.org/10.26434/che...

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It has been an exciting two days at the 2025 Exposome Bootcamp. Thanks to all of the participants and instructors. #exposomics #massspectrometry #geospatial #datascience

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Featured in the July issue of JASMS our #MOBIE platform enhances #PFAS isomer resolution and quantitation using high-resolution #SLIM based #IMS. Greater resolution = deeper insights in #exposomics & biomarker discovery. Read more: pubs.acs.org/doi/full/10....
#MassSpec #JASMS

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We are pleased to support our partner Dr. Erin Baker, as she presents the second plenary at the @metsoc.bsky.social conference 2025 in Prague! She’ll explore how #metabolomics + #exposomics reveal the true impact of #chemicalpollution.

📅 Tues, June 24 | 8:30–9:30 AM

#MOBIE

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🔬 New study uses alvaDesc to build a QSRR model for estimating plasticizer metabolite levels in urine

📄 Read the paper: doi.org/10.1016/j.ac...
🔗 Learn more about alvaDesc: alvascience.com/alvadesc/

#QSRR #alvaDesc #NTA #Exposomics #LCMS #Cheminformatics

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Brooklynn McNeil from Columbia University Mailman School of Public Health was recently interviewed about her #exposomics research for the GC Orbitrap Guru Series by @thermofishersci.bsky.social!

@exposome.bsky.social @exposomics.bsky.social

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Uncovering the Exposome: An Emerging Field Casts a Wide Net Researchers have long advocated for a more systematic approach to environmental health, but funding may not hold.

#exposomics featured in @undark.org!
The article "Uncovering the Exposome: An Emerging Field Casts a Wide Net" by Emma Foehringer Merchant discusses the field of exposomics and highlights both NEXUS and NEXUS collaborators!
Make sure to read!
undark.org/2025/06/16/u...

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Metabolon is proud to join @exposomemoonshot.bsky.social to explore how environmental exposure shapes health. By decoding the exposome, #exposomics can link exposure to environmental illness, drive innovation, and enable chronic disease prevention while shaping public health policies.

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