This review highlights #IGF2BP1 as a key #m6A reader that drives #cancer hallmarks by promoting the translation of #oncogenic RNAs, linking its overexpression to poor prognosis and therapy resistance, and discussing its potential as a #biomarker.
#OpenAccess: doi.org/10.1016/j.ge...
Scientists identify #IGF2BP1 as a driver of #ImmuneEvasion in C5 #OvarianCancer, suppressing IFN‑γ–IRF1–MHC‑I signaling and T‑cell infiltration; its inhibition restores #antitumor immunity and boosts #PD1blockade. @unihalle.bsky.social
#OpenAccess in #STTT: doi.org/10.1038/s413...
This review summarizes the current knowledge on the functional roles and underlying molecular mechanisms of #IGF2BP1 in regulating #cancer hallmarks and highlights its clinical significance as a #biomarker and a potential target for #tumortherapy. #medsky
#OpenAccess:
buff.ly/ZsXn477
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer
This review summarizes the current knowledge on the functional roles and underlying molecular mechanisms of #IGF2BP1 in regulating #cancer hallmarks and highlights its clinical significance as a #biomarker and a potential target for tumor therapy. #medsky
www.sciencedirect.com/science/arti...
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer
This review summarizes the current knowledge on the functional roles and underlying molecular mechanisms of #IGF2BP1 in regulating #cancer hallmarks and highlights its clinical significance as a #biomarker and a potential target for tumor therapy. #medsky
#OpenAccess: www.sciencedirect.co...
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer
This review summarizes the current knowledge on the functional roles and underlying molecular mechanisms of #IGF2BP1 in regulating #cancer hallmarks and highlights its clinical significance as a #biomarker and a potential target for tumor therapy. #medsky
#OpenAccess: www.sciencedirect.co...
