Meet with Andrea O'Hara, Ph.D. and nRichDX at #ASHG25 TODAY (10/16 2:30PM ET) 4055 Omics Technologies to learn about "cfRNA Cryptic Intron Identification from Liquid Biopsy Samples". Quick summary of the poster session here: hubs.ly/Q03NYxXv0

#LiquidBiopsy #Intron #ALS #GWZASHG #ASHG

Here you can see a cryoEM structure of Comamonas testosteroni KF-1 circularly permuted group II intron Pre-1S state (PDB code: 8XTS)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #intron #precursor #RNA #cryoem

Meet with Andrea O'Hara, Ph.D. and nRichDX at #ASHG25 (10/16 2:30PM ET) to learn about "cfRNA Cryptic Intron Identification from Liquid Biopsy Samples". Quick summary of the poster session here: hubs.ly/Q03Ngc150

#LiquidBiopsy #Intron #ALS #GWZASHG

The secret behind orange cats Why are cats orange? Meet Dr. Leslie Lyons, one of the world’s foremost experts in feline genetics. In this episode of Purr Podcast, we are demystifying orange cats! Dr. Lyons discusses new studies that revealed a never-before-seen genetic pathway for color pigmentation linked to orange cats.

📣 New Podcast! "The secret behind orange cats" on @Spreaker #cat #color #colorpatterns #exon #feline #gene #genetics #intron #orange #veterinary

Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes Group II Introns (G2Is) are large self-splicing ribozymes with promising biotechnological applications. This study utilized RNA inverse folding to design three novel G2Is. The designed intron Arq.I2,...

Have you ever wanted to design large and complex ribozymes from scratch? I know I have!

We used RNA inverse folding to design synthetic Group II Introns (G2Is) from the bottom up, resulting in highly active #ribozymes that splice in E. coli without proteins!

#intron #RNAsky #SynBio 🧬🧵(1/n)

Voice tech startup Intron launches new AI models amid broader sector expansion The launch comes as African startups develop multiple high-demand tools across various sectors to create additional re...

#News #Startups #AI #Healthcare #Intron #Nigeria

Origin | Interest | Match

The highly conserved intron of tyrosine tRNA is critical for m1A58 modification and controls the integrated stress response | PNAS tRNA introns are a universally conserved feature of eukaryotic genomes, but the reason for their conservation has remained obscure. We have previou...

#tRNA #Intron #ISR #Yeast

www.pnas.org/doi/10.1073/...

Comprehensive analysis of Saccharomyces cerevisiae intron structures in vivo - Nature Structural & Molecular Biology Here, Rangan et al. characterize S. cerevisiae intron structures with in vivo transcriptome-wide structure probing, showing that certain introns exhibit structural features that distinguish pre-mRNA f...

Nice!
#RNA #Intron #Scerevisiae

www.nature.com/articles/s41...

#quotes #books #booksky #excerpts #citations #howtogrowahuman #ball #gene #intron #jumpinggene #splicing #phylogeny #molbio #biology #dna

New vid on the yt channel
youtu.be/EGhHK0C_TmA?...

#Anime #Hoi4 #HOI4 #Blacksky #Intron #Digimon #Toei #Animation

#ERGAReads | Introns are abundant in eukaryotic #genomes, but their functions & evolution remain partially understood.

This study analyzes 590 species to explore #intron length, number & genome structure evolution across eukaryotic groups. 🧬

🔗 doi.org/10.1093/molb...

Free introns of tRNAs as complementarity-dependent regulators of gene expression Nostramo et al. demonstrate that free introns of tRNAs (fitRNAs) are a previously unknown class of small noncoding regulatory RNAs that bind to complementary sequences on mRNA ORFs, leading to decay. ...

Cool! Congrats!

#tRNA #Intron #fitRNA #BuddingYeast

Free introns of tRNAs as complementarity-dependent regulators of gene expression: Molecular Cell www.cell.com/molecular-ce...

It introduces a resource featuring 42k+ #intron sequences with precise boundaries, subtype classifications, & structural annotations. This database supports large-scale studies and engineering applications: https://doi.org/10.1093/bioadv/vbaf020

#Bioinformatics #RNA #Genomics

Meaning of #intron INTRON: Fragment of DNA that is not able to express themselves in form of protein... intron

Meaning of #intron INTRON: Fragment of DNA that is not able to express themselves in form of protein... intron

Intronic variant increases Parkinson disease risk by disrupting branchpoint sequence - Nature Structural & Molecular Biology A genetic variant specific to people of African ancestry increases the risk of neurodegenerative diseases, such as Parkinson disease (PD). This variant occurs in a noncoding region and interferes with...

#Intron #Variant #PD #Parkinson

www.nature.com/articles/s41...

Significado de #intron INTRÓN: Fragmento de ADN que no es capaz de expresarse en forma de proteína... intron

Significado de #intron INTRÃO: Fragmento de DNA que não é capaz de expressar-se na forma de proteína... intron

Significado de #intron INTRÃO: Fragmento de DNA que não é capaz de expressar-se na forma de proteína... intron

Protein-free catalysis of DNA hydrolysis and self-integration by a ribozyme Abstract. Group II introns are ancient self-splicing ribozymes and retrotransposons. Though long speculated to have originated before translation, their de

Out now in
@NAR_Open
! A #ribozyme can self-integrate into and hydrolyze ss- & dsDNA, offering a new avenue for the development of protein-free genome editing tools, and hinting at the possibility of a pre-translation origin of group II introns (G2Is). 🧬🧵 (1/7)
#intron #RNAworld

#biocuration reveals the truth! #Copepod Eurytemora affinis uses many non-canonical GA & GG 5' #intron donor splice sites & plays havoc with #gene predictors www.g3journal.org/content/early/2017/10/27...

Those who wanted refs on contrasting #intron #evolution in #mite & #tick #genomes see: http://gbe.oxfordjournals.org/content/8/6/1762.long & www.nature.com/ncomms/2016/160209/ncomm...