🔬 Research Spotlight
Our research team is co-culturing beta cells (green) with supporter MSCs (red). Beta cells migrate into islet-like structures, while MSCs may leave behind scaffolds for survival.

🚀 Stay tuned for more updates - we’re just getting started!
#kclt1diabetes #islettransplantation

Wonderful Wednesday in #YEG today #Oilers v #Panthers in the #StanleyCupFinal 25 years since the Edmonton Protocol changed diabetes care forever, From the rink to the lab Edmonton making history again #EdmontonProtocol25 #IsletTransplantation #T1D @edmontonoilers.bsky.social @ualberta.bsky.social

‘It literally saved my life’: Edmonton Protocol celebrates 25 years of success Twenty-five years ago, the U of A’s islet transplantation program revolutionized diabetes treatment. Today, researchers with the Alberta Diabetes Institute are continuing the quest to improve the Edmo...

25years ago, the Edmonton Protocol changed the lives people with #Type1Diabetes
“It literally saved my life,” says Rebecca Kalles Meng
A #Canadian breakthrough worth celebrating
🔗 ualberta.ca/en/folio/202... #EdmontonProtocol25 #IsletTransplantation
@ualberta.bsky.social

Can steroids save islets? New study shows that short-term high-dose methylprednisolone protects human pancreatic beta cells from inflammatory injury — reducing apoptosis, NF-κB signaling, and ER stress. @GlobalLumc #TXPforAll #islettransplantation tinyurl.com/y7twb3uz

Article in Press AND Open Access! "Cell therapy with human IL-10-producing ILC2s enhances islet function and inhibits allograft rejection" by Colpitts et al. doi.org/10.1016/j.aj... @sarahcolpitts.bsky.social @sarahcrome.bsky.social #celltherapy #islettransplantation

Sex Differences in Maturation and Function of Neonatal Porcine Islets Upon Transplantation in Mice Background Neonatal porcine islets (NPIs) can mature into a mixed population of endocrine cells that can restore glucose control in mice, pigs, and non-human primates, representing a potential alter...

Publication alert 🎉

Turns out sex does matter, at least when it comes to porcine islet transplantation. Female mice outperformed males in glucose control, proving once again that ignoring sex in science is just bad policy.
#Diabetes #IsletTransplantation

onlinelibrary.wiley.com/doi/10.1111/...

Th1nk Tank: Antonio Citro, PhD
🗓 Apr 24 | 🕛 12PM ET
🔬 Bioengineering a vascularized, iPSC-derived endocrine pancreas for T1D therapy
🔗 Join us! www.cell.com/cell-reports...
#T1D #iPSC #Bioengineering #RegenerativeMedicine #IsletTransplantation #StemCells #PancreasEngineering #Th1nkTank

The IsletTester Mouse: An Immunodeficient Model With Stable Hyperglycemia for the Study of Human Islets The gold standard for assessing the function of human islets or β-like cells derived from stem cells involves their engraftment under the kidney capsule of

#CRISPR/Cas9 gene editing establishes preclinical platform to evaluate #IsletTransplantation & #DrugDiscovery approaches doi.org/10.2337/db23... @kkaestner.bsky.social #DiabetesResearch #IsletBiology #TranslationalScience

The Islet Transplantation Laboratory moves to OR 14  | McGill University Health Centre Islet transplantation is a procedure in which insulin-producing cell clusters (islets) are purified from a deceased organ donor pancreas and transplanted into a type 1 diabetic patient. The transplant...

The MUHC's Islet Transplantation Laboratory, designated as the only facility in Quebec performing this life-changing procedure, has officially moved to OR 14 at the Royal Victoria Hospital. 🔬

#Innovation #IsletTransplantation #DiabetesCare

Islet transplantation with blood vessel cells shows promise to treat type 1 diabetes – BioNews Central A preclinical study showed that adding engineered blood vessel-forming cells to islet transplants enhanced insulin-producing cell survival and reversed type 1 diabetes, suggesting potential for wider use in diabetes treatment. ...

A #PreclinicalStudy showed that adding engineered #BloodVessel - forming cells to #PancreaticIslets transplants enhanced #insulin - producing cell survival and reversed #Type1Diabetes, suggesting potential for wider use in #DiabetesTreatment.
#IsletTransplantation #Type1DiabetesTreatment

🚨 Th1nk Tank Alert! 🚨

📢 Game-Changing Update in T1D Research

🔬 Discover breakthroughs in #HypoimmuneTherapy & #IsletTransplantation for #Type1Diabetes.

#T1DResearch #BetaCellReplacement #RegenerativeMedicine #StemCellTherapy #DiabetesInnovation #ClinicalTrials #PancreaticIslets #ImmunoEngineering