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New Journal for ImmunoTherapy of Cancer review: "γδ T cells at the interface of innate and adaptive immunity in cancer" https://jitc.bmj.com/content/14/3/e013668🧪

#JITC #cancer

New Journal for ImmunoTherapy of Cancer review: "γδ T cells at the interface of innate and adaptive immunity in cancer" https://jitc.bmj.com/content/14/3/e013668🧪 #JITC #cancer

New Journal for ImmunoTherapy of Cancer review: "γδ T cells at the interface of innate and adaptive immunity in cancer" jitc.bmj.com/content/14/3...

#JITC #cancer

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New Journal for ImmunoTherapy of Cancer article: "Intratumoral PD-1-directed IL-2 expression via oncolytic vaccinia virus elicits superior antitumor effects with enhanced safety" https://jitc.bmj.com/content/14/3/e011340🧪

New Journal for ImmunoTherapy of Cancer article: "Intratumoral PD-1-directed IL-2 expression via oncolytic vaccinia virus elicits superior antitumor effects with enhanced safety" https://jitc.bmj.com/content/14/3/e011340🧪

New Journal for ImmunoTherapy of Cancer article: "Intratumoral PD-1-directed IL-2 expression via oncolytic vaccinia virus elicits superior antitumor effects with enhanced safety" jitc.bmj.com/content/14/3...

#JITC #immunosky

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Targeting endosomal trafficking-mediated antigen escape to resensitize myeloma to CAR-T therapy Background Antigen escape is one of the leading causes of relapse following chimeric antigen receptor (CAR)-T therapy, particularly in multiple myeloma. A critical gap persists in understanding the tu...

New Journal for ImmunoTherapy of Cancer article: "Targeting endosomal trafficking-mediated antigen escape to resensitize myeloma to CAR-T therapy" jitc.bmj.com/content/14/3...

#JITC #research #ImmunoSky

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TCR sequencing in cancer immunology and immunotherapy: what, when, where, why, and how T-cell receptors (TCRs) are generated through somatic recombination of variable (V), diversity (D), and joining (J) gene segments, resulting in an extraordinarily diverse receptor repertoire that is e...

New Journal for ImmunoTherapy of Cancer review: TCR sequencing in cancer immunology and immunotherapy: what, when, where, why, and how jitc.bmj.com/content/14/3...

#JITC #cancer

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New Journal for ImmunoTherapy of Cancer article: Influence of body composition on the efficacy of nivolumab plus ipilimumab for metastatic clear cell renal cell carcinoma jitc.bmj.com/content/14/3...

#JITC #research

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New Journal for ImmunoTherapy of Cancer Commentary on “Comparative efficacy and safety of PSCA CAR-engineered Vδ1 γδ T cells for immunotherapy of pancreatic cancer
jitc.bmj.com/content/14/2...

#JITC #cancer

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New Journal for ImmunoTherapy of Cancer review: Unlocking the promise of innate biology through the HLA-G/ILT2/ILT4 pathway https://jitc.bmj.com/content/14/2/e013313

@jasonlukemd.bsky.social 
#JITC #cancer #research #ImmunoSky 🧪

New Journal for ImmunoTherapy of Cancer review: Unlocking the promise of innate biology through the HLA-G/ILT2/ILT4 pathway https://jitc.bmj.com/content/14/2/e013313 @jasonlukemd.bsky.social #JITC #cancer #research #ImmunoSky 🧪

New Journal for ImmunoTherapy of Cancer review: Unlocking the promise of innate biology through the HLA-G/ILT2/ILT4 pathway jitc.bmj.com/content/14/2...

@jasonlukemd.bsky.social
#JITC #cancer #research #ImmunoSky 🧪

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In honor of National #CancerPreventionMonth, the Feb. Issue of the #JITC Digest features a commentary from Dr. Olja Finn focused on the global need to prevent cancer. Explore her expert analysis and access cutting-edge articles on evolving biomarkers: https://ow.ly/yqFG50YhIl0

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New Journal for ImmunoTherapy of Cancer article: Oral immunization with Listeria monocytogenes vaccine enhances immunotherapy for protective immunity in murine models of colorectal cancer jitc.bmj.com/content/14/2...

#JITC #cancer

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Targeting RRBP1 reverses immune evasion and enhances immunotherapy efficacy via the CXCL10-CXCR3 axis in bladder cancer Background Crosstalk between inflammation and the immune system plays an important role in tumor malignant progression, immune evasion, and immunotherapy efficacy. This study aims to explore the signi...

New Journal for ImmunoTherapy of Cancer article: Targeting RRBP1 reverses immune evasion and enhances immunotherapy efficacy via the CXCL10-CXCR3 axis in bladder cancer
jitc.bmj.com/content/14/2...

#JITC #MedSky

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New Journal for ImmunoTherapy of Cancer article: MMP3 overexpression enhances CAR-T cell infiltration and antitumor activity in a CAF-enriched solid tumor model https://jitc.bmj.com/content/14/1/e013211

#JITC #MedSky 🧪

New Journal for ImmunoTherapy of Cancer article: MMP3 overexpression enhances CAR-T cell infiltration and antitumor activity in a CAF-enriched solid tumor model https://jitc.bmj.com/content/14/1/e013211 #JITC #MedSky 🧪

New Journal for ImmunoTherapy of Cancer article: MMP3 overexpression enhances CAR-T cell infiltration and antitumor activity in a CAF-enriched solid tumor model jitc.bmj.com/content/14/1...

#JITC #MedSky 🧪

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New Journal for ImmunoTherapy of Cancer article: Non-superagonist CD28-based dual-signal T cell engager targeting https://jitc.bmj.com/content/14/1/e013246

#JITC #ImmunoSky🧪

New Journal for ImmunoTherapy of Cancer article: Non-superagonist CD28-based dual-signal T cell engager targeting https://jitc.bmj.com/content/14/1/e013246 #JITC #ImmunoSky🧪

New Journal for ImmunoTherapy of Cancer article: Non-superagonist CD28-based dual-signal T cell engager targeting jitc.bmj.com/content/14/1...

#JITC #ImmunoSky🧪

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The January issue of the #JITC Digest features highlighted manuscripts examining gastrointestinal malignancies, along with key insights from Dr. Kimryn Rathmell’s plenary address at the #ASCO Gastrointestinal Cancers Symposium. Read the issue: https://ow.ly/luZq50Y0Jqx

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Screenshot of new commentary by Dr. Olja Finn from the University of Pittsburgh Department of Immunology titled "Opportunity knocking: shared tumor-associated antigen vaccines against global cancer pandemic."

Screenshot of new commentary by Dr. Olja Finn from the University of Pittsburgh Department of Immunology titled "Opportunity knocking: shared tumor-associated antigen vaccines against global cancer pandemic."

In a new @sitcancer.bsky.social #JITC commentary, Dr. Olja Finn makes the case that tumor-associated antigen vaccines, which failed as monotherapies, should be reconsidered as combination therapies with checkpoint inhibitor #immunotherapy for the treatment and prevention of #cancer.

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New Journal for ImmunoTherapy of Cancer case report: Intratumoral dendritic cell immunotherapy controls dissemination of metastasis-initiating cancer cells, even in patients with metastatic breast cancer jitc.bmj.com/content/14/1...

#JITC #MedSky

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New Journal for ImmunoTherapy of Cancer article: Single-cell and spatial transcriptome profiling identifies the immunosuppressive spatial niche in KRAS-mutant colorectal cancer https://t.co/D0t9Fj2UAm

#JITC #MedSky #ImmunoSky 🧪

New Journal for ImmunoTherapy of Cancer article: Single-cell and spatial transcriptome profiling identifies the immunosuppressive spatial niche in KRAS-mutant colorectal cancer https://t.co/D0t9Fj2UAm #JITC #MedSky #ImmunoSky 🧪

New Journal for ImmunoTherapy of Cancer article: Single-cell and spatial transcriptome profiling identifies the immunosuppressive spatial niche in KRAS-mutant colorectal cancer t.co/D0t9Fj2UAm

#JITC #MedSky #ImmunoSky 🧪

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New Journal for ImmunoTherapy of Cancer review: Cytotoxic CD4+ T cells in cancer: an emerging target for next-generation anticancer immunotherapy? t.co/kFxqcpVxOS

#JITC #ImmunoSky

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New Journal for ImmunoTherapy of Cancer article: In situ DC-primed vaccine combined with CD137 agonist elicits long-lasting antitumor immunity through cDC1-mediated tumor antigen-specific CD8+ T cell responses https://t.co/MH5lQvHMLw 🧪

#JITC #MedSky #ImmunoSky

New Journal for ImmunoTherapy of Cancer article: In situ DC-primed vaccine combined with CD137 agonist elicits long-lasting antitumor immunity through cDC1-mediated tumor antigen-specific CD8+ T cell responses https://t.co/MH5lQvHMLw 🧪 #JITC #MedSky #ImmunoSky

New Journal for ImmunoTherapy of Cancer article: In situ DC-primed vaccine combined with CD137 agonist elicits long-lasting antitumor immunity through cDC1-mediated tumor antigen-specific CD8+ T cell responses t.co/MH5lQvHMLw 🧪

#JITC #MedSky #ImmunoSky

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In the December #JITC Digest, Editor-in-Chief Dr. Michael Lotze highlights the latest developments and emerging trends in cancer immunotherapy. This month's selection of manuscripts features a fundamental focus on mechanisms of IO involving Tregs. Read the Dec. Issue: https://ow.ly/mwub50XL4o4

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New Journal for ImmoTherapy of Cancer article: Colorectal cancer organoids drive hypoxia, TGF-β, and patient-specific diversification of NK cell activation programs t.co/QTd6A59Ul5

#JITC #ImmunoSky

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As Fangling Ning presents data on SIRpα-fc fusion protein at #ESMOImmuno25, address blockade of CD47 with this recent #JITC article from Chilam Chan et al of UMC Utrecht: https://ow.ly/lbJV50XH7A5

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As Dimitrios A. Garyfallos shares new findings on, “In vivo CRISPR/Cas9 genetic screens identify novel immunotherapy target” at #ESMOImmuno25, discover more on CRISPR with #JITC!

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New Journal for ImmunoTherapy of Cancer article: Neutrophil extracellular traps–STC1 positive feedback loop promotes immune evasion and metastasis in bladder cancer jitc.bmj.com/content/13/1...

#JITC #MedSky

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New Journal for ImmunoTherapy of Cancer article: Engineering TME-activated CD47-specific CAR macrophage via Arg1 promoter for safe and effective solid tumor immunotherapy
t.co/xYSEvcRGST

#JITC #ImmunoSky

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🚀 just published @sitcancer.bsky.social #JITC

👥 34,973 pts
♻️ 47 #RCT
💉 PD-1 the earlier the better
HR=0.74
📌 #PFS2 great correlation to #OS
R² 0.74 #PFS2 vs 0.39 #PFS

Led by Dr. Jimenez-Labaig

@oncoalert.bsky.social @brunolarvol.bsky.social @vhio.bsky.social
👇🏽
jitc.bmj.com/content/jitc/1…

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In the Nov. Issue of the #JITC Digest, Editor-in-Chief Dr. Michael T. Lotze reflects on his experience at #SITC25 and several recent IO meetings. Explore his curated selection of cutting-edge articles, including new insights on LAG-3 blockade and more. View the Nov. Issue: https://ow.ly/fTO150Xun1R

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New Journal for ImmunoTherapy of Cancer review: Myeloid metabolism and its role in immunotherapy of cancer https://jitc.bmj.com/content/13/11/e012127

#JITC #MedSky 🧪

New Journal for ImmunoTherapy of Cancer review: Myeloid metabolism and its role in immunotherapy of cancer https://jitc.bmj.com/content/13/11/e012127 #JITC #MedSky 🧪

New Journal for ImmunoTherapy of Cancer review: Myeloid metabolism and its role in immunotherapy of cancer jitc.bmj.com/content/13/1...

#JITC #MedSky 🧪

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New Journal for ImmunoTherapy of Cancer review: Chimeric antigen receptor (CAR) T-cell therapy for glioblastoma (GBM): current clinical insights, challenges, and future directions https://jitc.bmj.com/content/13/10/e012308 

#JITC #ImmunoSky 🧪

New Journal for ImmunoTherapy of Cancer review: Chimeric antigen receptor (CAR) T-cell therapy for glioblastoma (GBM): current clinical insights, challenges, and future directions https://jitc.bmj.com/content/13/10/e012308 #JITC #ImmunoSky 🧪

New Journal for ImmunoTherapy of Cancer review: Chimeric antigen receptor (CAR) T-cell therapy for glioblastoma (GBM): current clinical insights, challenges, and future directions jitc.bmj.com/content/13/1...

#JITC #ImmunoSky 🧪

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Great panel discussion with speakers from the #WIC2025 #Tumor #Micro #Environment ( #TME ) session / chaired by Prof. Joe Yeong / Prof. Lotze notes possible role for early T cell infiltration into post-partum breast tissue #JITC #SITC2025

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New Journal for ImmunoTherapy of Cancer commentary: Role of cDC2 in priming CD8+ T cells in cancer https://jitc.bmj.com/content/13/10/e011519

#JITC #MedSky 🧪

New Journal for ImmunoTherapy of Cancer commentary: Role of cDC2 in priming CD8+ T cells in cancer https://jitc.bmj.com/content/13/10/e011519 #JITC #MedSky 🧪

New Journal for ImmunoTherapy of Cancer commentary: Role of cDC2 in priming CD8+ T cells in cancer jitc.bmj.com/content/13/1...

#JITC #MedSky 🧪

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