Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1-/- plus mtDNA mutant mice - Nature Communications Patients with primary mitochondrial disease manifesting cardiomyopathy are twice as likely to die compared to those without cardiomyopathy. Here, the authors show that a modest increase in cardiac mit...

#TargetedGeneTherapy for partial restoration of #MitochondrialFunction and protection against #DilatedCardiomyopathy www.nature.com/articles/s41... #MitochondrialCardiomyopathy #CardiacFunction #PGC1α #TranslationalScience

Top Cited Review Article, "Mitochondrial Calcium Regulation of Cardiac Metabolism in Health and Disease"

Enrique Balderas, et al.
doi.org/10.1152/phys...
#HeartFailure #MitochondrialCardiomyopathy