Function ☕ Monday Insights: Congrats 🎖️ to @edenmgallegos et al., for their #APSselect paper evaluating the effects of ethanol, sugars, and fats on hepatocyte #LipidMetabolism, #OxidativeStress, and #MitochondrialFunction in a spheroid model. Read doi.org/10.1093/func... #MetALD

Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1-/- plus mtDNA mutant mice - Nature Communications Patients with primary mitochondrial disease manifesting cardiomyopathy are twice as likely to die compared to those without cardiomyopathy. Here, the authors show that a modest increase in cardiac mit...

#TargetedGeneTherapy for partial restoration of #MitochondrialFunction and protection against #DilatedCardiomyopathy www.nature.com/articles/s41... #MitochondrialCardiomyopathy #CardiacFunction #PGC1α #TranslationalScience

Age Doesn't Define Your Energy - Chris Masterjohn with Joe Rogan

#control #mitochondrialfunction

Bezafibrate improves mitochondrial function, blood-brain barrier integrity, and social deficits in models of 22q11.2 deletion syndrome Pharmacological recovery of mitochondrial function improves blood-brain barrier function and cognition in 22q11.2 deletion syndrome, a risk factor for schizophrenia.

Characterizing the role of #Mitochondria in the #BloodBrainBarrier (BBB) & how impaired #MitochondrialFunction within the BBB relates to disease expression doi.org/10.1126/scit... #Neuroscience #TranslationalScience

August 26 Seminar “Metabolic and physiological implications of flexibility in the electron transport chain” by Jessica Spinelli PhD, Assistant Professor, Program in Molecular Medicine UMass Chan Medical School Host: Tigist Tamir 8/26/2025 @11AM in 1131 Bioinf bldg.

Seminar Aug. 26 11 AM
“Metabolic and physiological implications of flexibility in the electron transport chain” - Jessica Spinelli PhD, Asst. Professor, Program in Molecular Med., UMass Chan Medical School, Host: Dr. Tamir, Venue: 1131 Bioinf bldg. #MitochondrialFunction #ETC #MetabolicFlexibility

Human IRAK kinases differentially alter metabolic regulation and mitochondrial function in Saccharomyces cerevisiae
Cid, V. J., del Val, E. et al.
Paper
Details
#IRAKKinases #MitochondrialFunction #YeastMetabolism

Hemoglobin alpha regulates T-lymphocyte activation and mitochondrial function
Case, A. J., Griffin, B. L. et al.
Paper
Details
#HemoglobinAlpha #TCellActivation #MitochondrialFunction