I am excited to share with you an amazing video on the NLRP3 inflammasome pathway generated by talented Ann Liu from the Janet Iwasa lab @jiwasa.bsky.social @ann-hl.bsky.social. It shows the real structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. Enjoy!

#InfluenzaAVirus infection upregulates #NINJ1, driving inflammatory cell lysis during #PANoptosis, while NINJ1 deficiency reduces #LungInjury and mortality, underscoring its role in viral #pneumonia. @tsinghuauniversity.bsky.social

#OpenAccess in #STTT: doi.org/10.1038/s413...