Suppression of miR-17 Alleviates Acute Respiratory Distress-associated Lung Fibrosis by Regulating Mfn2

This study shows that #miR-17 inhibition alleviates ARDS-associated #PulmonaryFibrosis in mice by reducing #LungInjury, #Collagen deposition, and #Inflammation, while promoting #Mitochondrial #Autophagy through Mfn2 regulation. #medsky

To read: doi.org/10.1007/s115...

#InfluenzaAVirus infection upregulates #NINJ1, driving inflammatory cell lysis during #PANoptosis, while NINJ1 deficiency reduces #LungInjury and mortality, underscoring its role in viral #pneumonia. @tsinghuauniversity.bsky.social

#OpenAccess in #STTT: doi.org/10.1038/s413...

PRDX4 regulates alveolar macrophage (AM)-driven #Inflammation and #PulmonaryFibrosis in #Silicosis by preventing PTEN homodimerization and sustaining AKT/NF-κB activation, thereby exacerbating #LungInjury.

#STTT #OpenAccess: doi.org/10.1038/s413...

A Case of Drug-Induced #LungInjury With Systemic Features Resembling DRESS Caused by #Saiko-Ka-Ryukotsu-Borei-To and #Goreisan
onlinelibrary.wiley.com/doi/10.1002/...

CXCL5 does more than recruit neutrophils — it directly disrupts the alveolar–epithelial barrier.

Targeting CXCL5 could help preserve lung integrity during severe pneumonia.

#LungInjury #Immunology #Pneumonia

Redirecting

New paper from the Nouailles Lab! 🧬
@mucosalimmunol.bsky.social
Co–first authors Sarah Berger, @cgokeri.bsky.social & Peter Pennitz show that CXCL5 not only attracts neutrophils but also weakens the lung barrier in pneumonia.
Read it here: doi.org/10.1016/j.mu...

#LungInjury #Pneumonia #CXCL5

#Rituximab and #Pirfenidone in the Treatment of Steroid-Refractory #Bleomycin #LungInjury
onlinelibrary.wiley.com/doi/10.1002/...

This month's Editor's choice article is:
Clinical Presentation and Diagnostic Evaluation of #Vaping Related #LungInjury in #Youth
onlinelibrary.wiley.com/doi/10.1111/...

This study demonstrates that TAZ facilitates the deposition of H2A.Z at the IL-6 gene promoter, thereby enhancing IL-6 expression in #hypoxic #AlveolarEpithelialCells (AECs), ultimately mitigating hypoxic condition-induced #lunginjury. #medsky
#OpenAccess:
buff.ly/z2uKrRc

The Protective Effect and Mechanism of Mild Hypothermia on Lung Injury after Cardiopulmonary Resuscitation in Pigs

www.dl.begellhouse.com/journals/2ff...

#LungInjury #TherapeuticHypothermia #ResuscitationResearch #TranslationalMedicine

The Protective Effect and Mechanism of Mild Hypothermia on Lung Injury after Cardiopulmonary Resuscitation in Pigs

www.dl.begellhouse.com/journals/2ff...

#LungInjury #TherapeuticHypothermia #ResuscitationResearch #TranslationalMedicine

#Rifampicin-Induced #LungInjury in #Mycobacterium shinjukuense Infection: A Case Report
onlinelibrary.wiley.com/doi/10.1002/...

Selfie

Presenting our multiomic STOP BPD in session B14 study while @ambaln.bsky.social simultaneously presents the validation work on Let-7b in B18. #ATS2025 #science #lungdevelopment #lunginjury #prematurity

Clinical Presentation and Diagnostic Evaluation of #Vaping Related #LungInjury in Youth
#EVALI

Dynamic behavior and lineage plasticity of the pulmonary venous endothelium - Nature Cardiovascular Research Wong et al. identify Slc6a2 as a marker of pulmonary venous endothelial cells and demonstrate that these cells differentiate into capillary endothelial cells during vascular regeneration after lung in...

Shift in understanding: Progenitor capacity of pulmonary venous endothelial cells drives #LungInjury repair doi.org/10.1038/s441... #PulmonaryFunction #LungHealth
@vaughandy.bsky.social
#TranslationalScience

Injury From Nematode Lung Migration Induces an IL‐13‐Dependent Hyaluronan Matrix A consistent feature of lung injury is a rapid and sustained accumulation of hyaluronan (HA). The rodent gut-dwelling nematode Nippostrongylus brasiliensis (Nb) induces tissue damage as it migrates t....

🎉 the 1st paper from my post-doc is published 🎉 We found that #lunginjury caused by migration of N.brasiliensis induces an #IL-13 dependent #hyaluronan matrix. onlinelibrary.wiley.com/doi/full/10....