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Image shows a mitochondrion. In the lower left, fragmented lines represent impaired energy production and cellular stress in diseased cells. From the upper right, a blue light wave symbolizes the sildenafil intervention displacing the visual noise associated with mitochondrial dysfunction

Image shows a mitochondrion. In the lower left, fragmented lines represent impaired energy production and cellular stress in diseased cells. From the upper right, a blue light wave symbolizes the sildenafil intervention displacing the visual noise associated with mitochondrial dysfunction

#NotTheCover We proposed this image for our paper
out now in CELL @cellpress.bsky.social

It depicts sildenafil treatment like a wave displacing the visual noise associated with mitochondrial dysfunction.

Fantastic work from Emma Vidal at DrawImpacts!

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Fly primary neurons arranged in a circle, tubulin
 labelled in green, actin in magenta.

Fly primary neurons arranged in a circle, tubulin labelled in green, actin in magenta.

Our article on how GSK3b controls microtubule bundling in axons is live 🎉
Here's our #notthecover attempt
www.pnas.org/doi/10.1073/...

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Our article on how to use micropatterned presynapses-on-glass is out in its final form in the latest issue of the Journal of Neuroscience @sfnjournals.bsky.social: www.jneurosci.org/content/46/8...
The cover went to the special section on social neuroscience, so here's our #notthecover attempt

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#NotTheCover (harking back to the Twitter times!)

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Breaking symmetry♋️

Another #NotTheCover from the same issue of @cellcellpress.bsky.social

Here the @zernickagoetz.bsky.social lab @caltech.edu reports the earliest known symmetry breaking event in the mammalian embryo - right at moment of fertilisation!

#sciart #scicomm 🧵

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We also had another attempt #NotTheCover, this time hand-drawn by @bioarm.bsky.social one of the co-first authors of this work.
This will also be printed out.

& if you wonder what the real cover ended up, it was an axolotl... yet again!

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Another #notTHECover unfortunately.

But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab.

Read here: www.cell.com/cell/fulltex...

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Bifidobacteria co-evolve with their hosts - new research by the @halllab.bsky.social published in @cp-cellhostmicrobe.bsky.social and illustrated by me!

Another #NotTheCover for the books, but in this case, it's really their loss 😋

🧫🧪🐡 #microbiome #cartoon

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#NotTheCover @cellpress.bsky.social ...but, we’re still pretty proud of it! 😄 Had an awesome time putting this together with the amazing @kfreeman.bsky.social and @raphaelpark.bsky.social What a ride! 🚀
#SciArt #CryoET #CryoEM

Paper👉 www.cell.com/cell/fulltex...

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How this image is #notthecover? It's the coolest one I've seen in a while! All praise to M, our microglia savior, for destroying amyloid and rescuing neurons!

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Our Immunity @cp-immunity.bsky.social Cover was not selected but nothing can hold back the Microglia super-heroine when she has DGAT2-blocking beverage. #NotTheCover Read the full article in Immunity: www.cell.com/immunity/ful...

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Preview
Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease Why microglia stop reducing amyloid deposits from Alzheimer’s disease (AD) brains is unknown. Prakash, Manchanda, et al. show that microglia increase their lipid droplets and lose their phagocytic cap...

Bummed we didn’t get the cover, but absolutely thrilled that Emma Videl (drawimpacts) brought our microglia superhero vision to life in the most fantastic way! 🦸‍♀️🧠💥

#SciArt #Alzheimers #Microglia #Immunity#notthecover

www.cell.com/immunity/ful...

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Meet M, our microglia superheroine 🦸‍♀️💥

After chugging the magical DGAT2-Stop! Kool-Aid 💊🧃, she breaks free from her lipid droplet shackles 💥💪

Supercharged, she lifts the amyloid beams 🧱 trapping neurons and saves the city of Brain 🧠🏙️!

Our cover submission for @cp-immunity.bsky.social. #notthecover

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#notthecover, but it’s beautiful and captures the science so well! Thank you for sharing your creative vision with us!

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Microglia: A super-heroine that had a DGAT2-blocking beverage (cans) so she could break the chains from lipid droplets holding her back (LD weights) and lift the amyloid load (beams) that trapped the neurons, thereby rescuing them in the aged Brain (City sign)! #NotTheCover @cp-immunity.bsky.social

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I also had fun in making gummy GLT25D1 making #notthecover using #blender

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#notthecover
Friction (rather than density of motors) guides actin network contraction. #resistance
by @alexandra-colin.bsky.social
www.pnas.org/doi/10.1073/...

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Illustration of a forest across seasons with immunofluorescence images of tumor microarrays as “leaves”

Illustration of a forest across seasons with immunofluorescence images of tumor microarrays as “leaves”

#notthecover but still love this illustration by Ella Maru representing our multiparameter image analysis pipeline to reveal clinically relevant cancer phenotypes. Now out it print www.cell.com/cell/fulltex...

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Thing 3 to gain attention and followers: This was #NotTheCover of JCB - 3D rendering of a bunch of cancer cells imaged in zebrafish, pseudocolored by morphotype (e.g. shape classification)

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Thanks to all our amazing collaborators in Japan🇯🇵 (Ginga, Yusuke, Aki, Genji), UK🇬🇧 (Onyou, Sabina, @jnb-lab.bsky.social, Luke) & France🇫🇷 (@serenaflori.bsky.social, Giovanni). And huge congrats to Manon Demulder!👩‍🔬💪

Here's a beautiful #NotTheCover of diatoms on a grid by Martin Oeggerli #SciArt🧪🎨 7/🧵

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#NOTtheCover #ProtistsOnSky
Unfortunately, we didn't make the cover @natureportfolio.bsky.social .

I still think our proposition deserves sharing.

Enjoy the read: www.nature.com/articles/s41...

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BONUS #NotTheCover behind the scenes! Here you can see the painstaking process of science artist Martin Oeggerli (https://www.micronaut.ch/ coloring in all the details by hand🧑‍🎨🖌️. He made sure to get the color of the copper grid bars JUST right!🫶

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#NotTheCover @CellCellPress but I want to share this beautiful colorized image of diatom cells on an EM grid before FIB milling. This stage of the workflow isn't shown in our PyShell papers.

Fantastic work by @benoitgallet & Martin Oeggerli.

The papers:...

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grumpy cat unumused by having another great cover concept killed by the journal

grumpy cat unumused by having another great cover concept killed by the journal

Guess who has two thumbs and just got *another* #notthecover

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For #FluorescenceFriday, another #notthecover from our recent @JCellBiol article! Beads making presynapses on axons

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Let's have a #notthecover for #MicroscopyMonday: hippocampal neuron with endogenously tagged HA-actin (one of the proposed covers for rupress.org/jcb/article-abstract/222...

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For #FluorescenceFriday, here's an SMLM kaleidoscope! #notthecover from @FriedlKaroline's recent article https://doi.org/10.1016/j.crmeth.2023.100571

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And just for fun, here is our #NotTheCover 🥲

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Original thread - @CellfOrganized coined the #notthecover hashtag! twitter.com/CellfOrganized/status/82...

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It's called #notthecover and @ManuelTHERY et al. started it back in 2017. Check the hashtag! @rita_strack twitter.com/OdedRechavi/status/14617...

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