How to build a normal multilayered arterial wall?😎

Activated Sphingosine kinase 1 mediates elastin deficiency-induced arterial hypermuscularization🐭

Both Smooth muscle cell & Endothelial cell contribute

@junichisaito.bsky.social @greiflab.bsky.social #NatCVR 2026
www.nature.com/articles/s44...

#SpatialTranscriptomics Stereo-seq 👤Carotid #Atherosclerosis

IntraPlaque #TertiaryLymphoidOrgan😎
CD138+ Plasma cells +diverse B cells

❎ #GerminalCenter
✅ #Lymphangiogenesis ✅#HEV
Col5A1+ fibroblast-like #SmoothMuscleCell as #LymphoidTissueOrganizer

#NatCVR 2025
www.nature.com/articles/s44...