¿Puede la sangre de pitón ayudar a adelgazar de verdad? #Ciencia #Salud #Obesidad #Metabolismo #Pitones #Ozempic #Wegovy #Semaglutida #Biomedicina #Investigacion #NatureMetabolism #PerdidaDePeso #felizviernes #20demarzo donporque.com/sangre-de-pi...
Out now in #NatureMetabolism 🧪
How does psychological stress influence tumor development?
Chronic stress disrupts catecholamine signalling, which in turn rewires the hepatic kynurenine pathway. This shift suppresses hepatic CD8⁺ T cell activity and promotes immune evasion.
📢Laboratory & Wildlife Newsletter December edition is out! Perfect reading during the holidays!
👉 tinyurl.com/2s3pb8ry
#tinytemperaturelogger #temperaturelogger #tinylogger #activitylogger #activitytemperaturelogger #metabolismresearch #NatureMetabolism #ScientificInnovation #MadeInIceland
Exercise Triggers Appetite‑Suppressing Molecule Lac‑Phe, Study Finds
Intense exercise raises Lac‑Phe, a metabolite that cut food intake and weight in mice and was linked to abdominal‑fat loss in humans; the finding appears in Nature Metabolism. Read more: getnews.me/exercise-triggers-appeti... #lacphe #naturemetabolism
Out now in #NatureMetabolism 🧪
This year marks 20 years since the first GLP-1R agonist was approved. Former employees at Amylin Pharmaceuticals look back on how it all began.
Led by James Trevaskis.
Out now in #NatureMetabolism 🧪
Preferential use of gluconeogenic pathways in the liver depends on exercise load and affects performance.
For an extra read on our new publication in #naturemetabolism, read my Blog Post: Unravelling how the stress sensor ATF6 stirs up trouble (and tumors)
communities.springernature.com/posts/unrave...
#lifesciences #colorectalcancer #microbiota #erstress #metabolism
What happens when #mitochondria fail in high-energy tissues? Cells adjust their metabolism and alter the mechanics of the nucleus! Read more on the discovery by Dr. Harshita Kaul from the Trifunovic Lab in Nature Metabolism.
➡️ uni.koeln/QZURH
#CellStress #NatureMetabolism @unicologne.bsky.social
Out now in #NatureMetabolism 🧪
In this double-blind, randomised, crossover trial, a diet rich in fermentable foods was shown to improve the glucose-lowering efficacy of metformin in people with prediabetes due, at least in part, to changes in gut microbiota composition.
doi.org/10.1038/s422...
Out now in #NatureMetabolism 🧪
This study shows that, compared to plant-based fats, animal-based fats accelerate tumour growth and impair anti-tumour response to melanoma in obese mice.
Same calories, different outcomes!
From the lab of @lydialynch.bsky.social
doi.org/10.1038/s422...
Out now in #NatureMetabolism 📢
In the newest installment of our Metabolic Messengers series, Hevener and Correa provide a comprehensive overview of the preclinical and clinical evidence showing the metabolic role of oestradiol and its receptors in both women and men.
Out now in #NatureMetabolism 📢
Grouped data are very common in preclinical studies, and can artificially inflate statistical significance. In this Comment, the authors define grouped data, and provide best practices to account for them from the experimental design to the data analysis stage.
Out now in #NatureMetabolism 📢
In this randomized crossover study, human gastrointestinal digesta were collected using a unique intubation technique to compare how meals with contrasting cellular structures affect postprandial luminal metabolites, glycaemia, gut hormones and satiety sensation.
Out now in #NatureMetabolism 📢
Nuclear SREBP2 forms nuclear condensates through its N-terminal intrinsically disordered region, which is essential for the transcriptional activation of lipogenic genes.
Out now in #NatureMetabolism 📢
MKK3b/6 signalling pathway drives the skeletal muscle growth-promoting effects of resistance exercise.
Out now in #NatureMetabolism 📢
In the prospective, double-blind, randomized, placebo-controlled, COVit-2 trial, supplementation with a combination of conventional and gut-targeted nicotinamide was safe and effective in ameliorating COVID-19 symptoms.
Out now in #NatureMetabolism 📢
Read about the gender, career stage and geographical distribution of our reviewers in this new Editorial.
Out now in #NatureMetabolism 📢
ERαvlVMH neurons mediate the inhibitory role of 17β-oestradiol on prolactin production, and this inhibition is lifted in lactating mice to promote lactation-associated metabolic adaptations.
Out now in #NatureMetabolism 📢
In humans, conception during cold seasons is shown to exhibit higher brown adipose tissue activity and adaptive thermogenesis, and lower body mass index and visceral fat accumulation in the offspring.
Out now in #NatureMetabolism 📢
FGF19 increase in post-bariatric hypoglycaemia is mediated by bile acid dysregulation, and can be countered by inhibiting bile acid transport.
A personal interest in #motionSickness led them to discovering potential new options for treating #obesity. Drs. X.Xu & L Tu explain their findings. #NatureMetabolism @bcmhouston.bsky.social www.genengnews.com/topics/trans...
Out now in #NatureMetabolism 📢
In a randomized, crossover clinical trial in healthy young adults with varying weights, sucralose increased hypothalamic blood flow and its functional connections with brain regions involved in motivation and somatosensory processing.
Read about this fascinating study showing that brain myelin content is temporarily and reversibly diminished by severe exercise!
Out now in #NatureMetabolism
Out now in #NatureMetabolism 📢
Glutamatergic neurons in the parvocellular part of the medial vestibular nucleus mediate motion-induced hypothermia and can be targeted to prevent diet-induced obesity.
Out now in #NatureMetabolism 📢
This study shows that antipsychotic drugs induce metabolic dysfunction via prodynorphin-expressing ventromedial hypothalamus neuron suppression, which can be mitigated with GLP-2 receptor agonism.
Out now in #NatureMetabolism 📢
SIRT5 protects against primate skeletal muscle ageing through TBK1 desuccinylation, which inhibits downstream inflammatory and senescent phenotypes.
Out now in #NatureMetabolism 📢
Dietary protein restriction in healthy, lean men elicits an increased energy intake to maintain body weight, which is driven, at least in part, by FGF21-mediated alterations to adipose tissue mitochondria.
Out now in #NatureMetabolism 📢
Leveraging four large, longitudinal, prospectively-followed mother–child cohorts, this study shows that a western diet in early–mid-pregnancy is associated with neurodevelopmental disorders in the offspring.
Obesity Starts in the Brain
Obesity starts in the brain 🧠
A study by #HelmholtzMunich, University Hospital Tübingen and @diabresearch-dzd.bsky.social reveals new insights into the brain's role in type 2 diabetes and obesity.
👉Read more: t1p.de/huku3
#Brain #Obesity #Diabetes #Type2Diabetes #NatureMetabolism
is this normal? this shouldnt be allowed #naturemetabolism 🧪 #publishing woes (fortunately not mine... i dont have that kind of patience)
