One for #NeuralTube biologists:

Let me add our paper to this review of mechanical drivers of NT folding.

We showed that mammalian spinal #neuraltube folding is primarily driven by #mesoderm expansion and #zippering. #Hingepoints emerge as a result of these extrinsic forces.

www.pnas.org/doi/10.1073/...

x.com/DagmarIber/s...

Our postdoc Rohit Harish just presented his work on the regulation of spinal cord size during mouse development at our internal Neuro Data Talk seminar 👏 Great work, Rohit! We are all looking forward to seeing where your research leads us! 👀🔬🐀
#neurodevelopment #development #spinalcord #neuraltube

Retinoic acid induces human gastruloids with posterior embryo-like structures - Nature Cell Biology Hamazaki, Yang et al. report that an early pulse of retinoic acid robustly induces human gastruloids with a neural tube, segmented somites and more advanced cell types than conventional gastruloids.

#NCB2024
In August, @jshendure.bsky.social, Hamazaki & co reported that an early pulse of retinoic acid robustly induces human #gastruloids with a #NeuralTube, segmented #somites and more advanced cell types than conventional gastruloids.
www.nature.com/articles/s41...

3D reconstruction of a chick embryo neural tube (stage HH9), treated with a PKC agonist. View from the apical region. Modified from Aparicio et al., 2018 DOI: 10.1002/dvg.23104

3D reconstruction of a chick embryo neural tube (stage HH9), treated with a PKC agonist. View from the apical region.
Modified from Aparicio et al., 2018. DOI:10.1002/dvg.23104
🧪🔬🐥 #FluorescenceFriday #SciArt #Microscopy #neuraltube