Bursary for UK professionals to attend European Aniridia Conference 2026 Aniridia Network is offering to fund UK professionals to take part in this year's European Aniridia Conference (EAC), 17-19 April in Sofia, Bulgaria. EAC enables the sharing of scientific knowledge about the rare genetic eye condition aniridia. Its goal is to prevent sight loss and deal with aniridia’s effects. It brings together patients and the world’s top experts to upskill the clinical, research and aniridic communities.

Doctors and scientists working on #PAX6 & aniridia: don't miss out on attending the European Aniridia Conference in April 2026. #EuroAniridiaConf

Analysis of Phenotypes Associated with Deficiency of PAX6 Haplotypes in Chinese Aniridia Families

Researchers identified two novel #PAX6 mutations in Chinese #Aniridia families, expanding the genotypic and phenotypic spectrum and detailing the clinical traits of PAX6 haplotype deficiency. #medsky

Read more: link.springer.com/article/10.1...

In the apple eye of evolution: Camera-type eye regeneration - the Node Behind the paper stories from "A genetically tractable non-vertebrate system to study complete camera-type eye regeneration" We are all stepping into a

#ICYMI
Check out my new article at @the-node.bsky.social where Alice and Alejandro share #behindthepaper stories !

Come for the science, stay for learning about curiosity, philosophy, mentorship & joy of discovery!

#devbio #regeneration #stemcells #scicomm
#pax6 #cellbio #eye #organogenesis

Quote graphic featuring a photo of a human eye and the quote: "A wide variety of model systems have been utilised to understand the function of PAX6 in early eye development, but divergence of developmental mechanisms means findings do not always translate to humans ... Stem cell-derived 3D retinal organoids have become a robust tool for studying early eye development, with self-organisation of cells into distinct layers of the neural retina (NR) reflecting in vivo organogenesis." Attributed to Harding P, Owen N, et al. (2025). doi:10.1016/j.bbadis.2025.167869

Using patient-derived optic #organoids and #multiomics analysis, researchers discovered a new role for #PAX6 in regulating SOX2 and Notch signaling during early eye development, offering mechanistic insight into PAX6-related ocular disorders.

doi.org/10.1016/j.bb...

#devbio 🧪

This snail may hold a secret to human eye regeneration Golden apple snails can regrow full, functional eyes. Studying their genes may reveal how to repair human eye injuries.

“Understanding how the snails re-create or repair their eyes might lead to therapies to heal people’s eye injuries or reverse diseases such as macular degeneration.”

#scicomm
#regeneration
#crispr
#pax6

www.sciencenews.org/article/snai...
🧪 🧠 👁️ 🐚 🐙

Apply for our 2nd grant for UK aniridia research Apply for a £15k grant to collect preliminary/pilot data for later research into congenital aniridia.

UK doctors and scientists interested in #aniridia. We have a #grant for you cofunded with @fightforsight.bsky.social.
Application deadline 16 July 2025.
aniridia.org.uk/2025/06/03/a...
Please share.
#MedicalResearchFunding #ResearchGrants #RareDiseaseResearch #SightLossResearch #PAX6

Well done Dr Pippa Harding, my PhD student @ucleye.bsky.social who grew eye cups from a patient with a missense variant in the #PAX6 paired domain causing #microphthalmia & a typical #aniridia patient. SOX2 and Notch pathways were dysregulated. Disease insights: www.sciencedirect.com/science/arti...