Our next graphical abstract is by João Pinheiro who is engineering an ex vivo model of post-traumatic osteoarthritis (PTOA) at LifeTec Group, supervised by Dr Linda Kock. If you would like to know more about this project, please drop João a line: www.linkedin.com/in/joaomateu...
#MSCA_DN #OA #PTOA
#Article in #MedComm
Growth/Differentiation Factor 15 Promotes a Pro-Regenerative Response in Chondrocytes Upon Cartilage Injury doi.org/10.1002/mco2..., studied by Dr. @janariegger.bsky.social and her group.
#CellFateDecision #chondrocytes #PTOA #GDF15 #PosttraumaticOsteoarthritis
#New #Basic #Science in #OAC
How does sex influence the development of #PTOA using a mouse model of mechanical #ACL injury? 📑Check out this work:
www.sciencedirect.com/science/arti...
Figure showing associations between MRI findings and knee osteoarthritis outcomes
#MRI provides different data, w bone shape/position & cartilage morphology/composition giving some clues. Possibly in #PTOA, structural problems lead to compositional changes, vice versa in iOA. Heterogentity is an issue here too!
bit.ly/3GN8xoB
@oacjournal.bsky.social
Figure demonstrating the three tiers of prevention - primary, secondary and tertiary, with two text boxes, one outlining the roles of biomarkers and the other risk factors for osteoarthritis
Firstly, the population at risk and why #military individuals are at higher risk of #OA, especially #PTOA. We need to move from a management to prevention paradigm, and we need to improve identification tools such as biomarkers…
bit.ly/48HwZ4k
This month's #BasicScience #EditorsChoice paper demonstrates that the Maresin 1-LGR6 axis mitigates inflammation and #PTOA after transection of the #ACL in mice🐭. @lehoczky-lab.bsky.social
🔗sciencedirect.com/science/article/pii/S106...
