Endo grand rounds: adult endo fellow Dr Andrew Barr & Peds endo fellow Dr James Schuler presented interesting topics. 1st up: don’t forget primary #hypothyroidism can cause #pituitary hyperplasia which can mimic an adenoma. 2nd: teens w #DM1 can participate in extreme sports w proper precautions.

Sporadic #prolactinomas are the most common functioning #pituitary #adenomas, with a female predominance during reproductive years. In men, these adenomas are usually larger and more aggressive www.thelancet.com/journals/lan...
#hyperprolactinaemia

#MedSky #EndoSky

Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis The hypothalamic-pituitary-gonadal axis (HPG) controls pubertal development, sexual maturation, and fertility. We identified a role of hypothalamic microglia in controlling the HPG axis through recept...

This is a rather surprising finding!

#Microglia Rank signaling regulates GnRH #neuronal function and the #hypothalamic - #pituitary - #gonadal axis | Science www.science.org/doi/10.1126/...

1/5 psychologist Jerome Wodinsky showed that if he removed the optic gland from female Caribbean two-in spot octopuses (Octopus hummelincki), something interesting happened.

The optic gland is similar to the #pituitary #gland of most land animals, so-called because it sits between the eyes.

Prolactinomas are the most prevalent functional pituitary adenomas and can result in a proliferative endocrine disorder that is typically highly responsive to medical therapy www.thelancet.com/journals/lan...
#prolactinomas
#hyperprolactinaemia
#pituitary #adenomas

#MedSky #EndoSky #OncSky

Risk of recurrence after successful surgery for Cushing's disease and association with USP8 genotype and tumour size: an international, retrospective, longitudinal cohort study Combined USP8 genotype–tumour size identified patients at increased risk of recurrence, particularly in largely heterogeneous groups of patients with non-invasive tumours or low postoperative serum co...

Our results support a novel three-tier risk assessment system that integrates #USP8 #genetic status and tumour size to predict #recurrence after first #pituitary #surgery www.thelancet.com/journals/lan...
#Cushing's disease
#OpenAccess

#MedSky #EndoSky #OncSky

A Personal Pituitary Journey: From Pituitary Tumors to iPSCs-Based Models for Congenital Hypopituitarism - Endocrine News On behalf of the Endocrine Society’s Early-Career Special Interest Group, Maria Andrea Camilletti, PhD, takes us on a guided journey from family influences to how she developed such a keen interest in...

Maria Andrea Camilletti, PhD, takes us on a guided journey from family influences to how she developed such a keen interest in the #pituitary, and explains why it brings her so much joy. #endocrinology #EndoSky

endocrinenews.endocrine.org/a-personal-p...

Reversible Junctional Scotoma From Pituitary Adenoma During Pregnancy: Journal of Neuro-Ophthalmology
Article: bit.ly/JNO_self_res...
#brain #eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #pituitary @LSUHS

#Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such
as #prolactin-secreting #pituitary #adenomas and other pituitary stalk-compressing masses www.thelancet.com/journals/lan...
#prolactinomas

#MedSky #EndoSky #OncSky

#SimulAdren is a simulation program for the #hypothalamus - #pituitary - #adrenal feedback control, an essential physiological motif. It is written in #Object_Pascal and helps to understand life-threatening diseases.

Sporadic #prolactinomas are the most common functioning #pituitary #adenomas, with a female predominance during reproductive years. In men, these adenomas are usually larger and more aggressive thelancet.com/journals/lan...
#hyperprolactinaemia

#MedSky #EndoSky #OncSky

Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice Multiple endocrine neoplasia type 1 (MEN1) is characterised by combined occurrence of parathyroid tumours, duodenopancreatic neuroendocrine tumours, and anterior pituitary adenomas. Some patients migh...

Multiple endocrine neoplasia type 1 (#MEN1) is characterised by combined occurrence of #parathyroid tumours, #duodenopancreatic #neuroendocrine tumours, and anterior #pituitary adenomas thelancet.com/journals/lan...
#MEN1
#FREE to read with registration (also FREE)

#MedSky #EndoSky #OncSky

#Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as #prolactin-secreting #pituitary adenomas and other pituitary stalk-compressing masses www.thelancet.com/journals/lan...
#prolactinomas

#MedSky #EndoSky #OncSky

Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study Even in specialised centres, cCS diagnosis and management remain challenging with high rates of spontaneous adrenal insufficiency, inappropriate surgeries, and poor outcomes. Ectopic cCS showed the mo...

Even in specialised centres, cyclic #Cushing's syndrome (cCS) diagnosis and management remain challenging with high rates of spontaneous adrenal insufficiency, inappropriate surgeries, and poor outcomes thelancet.com/journals/lan...
#pituitary

#MedSky #EndoSky

Sporadic #prolactinomas are the most common functioning #pituitary #adenomas, with a female predominance during reproductive years. In men, these adenomas are usually larger and more aggressive www.thelancet.com/journals/lan...
#hyperprolactinaemia #prolactin

#MedSky #EndoSky #OncSky

Validation and Limitations of the PANOMEN-3 Predictive Model for Tumor Recurrence and Progression in Pituitary Tumors AbstractContext. It has been proposed that the PANOMEN-3 classification may be useful to guide the prognosis and therapy of patients with pituitary tumors

Validation and Limitations of the PANOMEN-3 Predictive Model for Tumor Recurrence and Progression in #Pituitary #Tumors academic.oup.com/jcem/article... #hvhebron #endo #ap [Text complet]

Transcriptomic Changes Across the HPG Axis Following Prenatal Exposure to the EDC Mixture NeuroMix Abstract. Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that are ubiquitous in our environment and found in everyday items. We previously r

Transcriptomic Changes Across the HPG Axis Following Prenatal Exposure to the EDC Mixture NeuroMix. Read more in #Endocrinology: bit.ly/3M2jRPK #Endocrine-DisruptingChemical #EDC #hypothalamus #pituitary @endocrinesociety.bsky.social

Sporadic #prolactinomas are the most common functioning #pituitary adenomas, with a female predominance during reproductive years. In men, these adenomas are usually larger and more aggressive www.thelancet.com/journals/lan...
#hyperprolactinaemia

#MedSky #EndoSky #OncSky

Hyperprolactinaemia can result from dopamine antagonist drug effects and reduced prolactin clearance with liver or kidney disease with loss of feedback regulation www.thelancet.com/journals/lan...
#hyperprolactinaemia #prolactinomas #pituitary

#MedSky #EndoSky

How can emerging tools transform care for patients with complex #pituitary and #neuroendocrine conditions?

The seventh paper in the #EndoCompass Research Roadmap focuses on pituitary and neuroendocrine tumour #endocrinology

Read the full findings 👇
doi.org/10.1093/ejen...

Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice Multiple endocrine neoplasia type 1 (MEN1) is characterised by combined occurrence of parathyroid tumours, duodenopancreatic neuroendocrine tumours, and anterior pituitary adenomas. Some patients migh...

Multiple endocrine neoplasia type 1 (#MEN1) is characterised by combined occurrence of #parathyroid tumours, #duodenopancreatic #neuroendocrine tumours, & anterior #pituitary adenomas www.thelancet.com/journals/lan...
#MEN1
#FREE to read w/reg (also FREE)

#MedSky #EndoSky #OncSky

Prolactin-secreting adenomas: pathogenesis, diagnosis, and management Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as prolactin-secreting pituitary adenomas and other pituitary stalk-compressing masses...

Prolactinomas are the most common pathological cause of hyperprolactinaemia and represent approximately half of pituitary adenomas thelancet.com/journals/lan...
#prolactinomas #hyperprolactinaemia #pituitary

#MedSky #EndoSky

Venous thromboembolism in patients with pituitary adenoma: UK multicentre cohort study AbstractObjective. This study aims to assess risk of venous thromboembolism (VTE) in patients with Cushing's disease (CD) compared to acromegaly and non-fu

Venous thromboembolism in patients with pituitary adenoma: UK multicentre cohort study by Kristina Isand et al

EJE Volume 193, Issue 2, August 2025
Open access article 👉 doi.org/10.1093/ejen...

#endocrinology #pituitary

New review from our group!

We explore the multifaceted roles of folliculostellate (FS) cells in the pituitary gland — from immune-endocrine regulation to their paradoxical effects on tumorigenesis and aging.

📘 Read it here: karger.com/nim/article/...

#pituitary #neuroendocrinology #aging

Did you know that the pituitary contains non-endocrine folliculostellate cells 🌟 (FS) that sense immune signals, regulate hormones, and influence tumorigenesis and inflammaging?
Excited to share our new review on the roles of FS cells⭐
doi.org/10.1159/0005...
#pituitary #inflammaging

#Prolactinomas are the most common pathological cause of #hyperprolactinaemia and represent approximately half of #pituitary #adenomas thelancet.com/journals/lan...
#pituitary

#MedSky #EndoSky

Our own Dr Maggie Wierman explains #pituitary tumors and the importance of multi-disciplinary care. @cudeptofmedicine.bsky.social
@cucancercenter.bsky.social

What’s a PitNET, and How are They Treated? At the CU Cancer Center, patients with pituitary tumors are evaluated and treated at the multidisciplinary Pituitary Tumor Program.

Dr Margaret Wierman, director of the #pituitary center, explains pituitary tumors and how best care occurs with a multi-disciplinary approach.

news.cuanschutz.edu/cancer-cente...

#Hyperprolactinaemia can result from dopamine antagonist drug effects and reduced prolactin clearance with liver or kidney disease with loss of feedback regulation thelancet.com/journals/lan...
#prolactinoma #pituitary #adenoma

#MedSky #EndoSky

Prolactin-secreting adenomas: pathogenesis, diagnosis, and management Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as prolactin-secreting pituitary adenomas and other pituitary stalk-compressing masses...

#Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as #prolactin-secreting #pituitary #adenomas and other pituitary stalk-compressing masses
www.thelancet.com/journals/lan...
#prolactinomas

#MedSky #EndoSky #OncSky