🧬 How do SARS-CoV-2 mutations boost fitness?
With ISIDORe, Blackledge (IBS Grenoble) used high-field NMR to show that N protein mutations (e.g. Q229K, R203M) reshape structure & RNA binding.
Disorder = function.
#ISIDORe #SARSCoV2 #Nucleocapsid #NMR #ViralFitness #ProteinDisorder
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