Icon of S. Charles, King and Martyr

Carolus Rex et Martyris, ora pro nobis. #SKCM #Narthex

SETDB1-H3K9me3 represses #EndogenousRetroVirus transcription

SETDB1 CRISPR KO⏫ERV➡️
⏫MDA5-MAVS RNA sensing➡️
⏫IRF7 interferon signal➡️
⏫T cell infiltr
⏫Irradiation sensitiv in B16F10 🐭tumor

SETDB1 ➖corr. #NSCLC #SKCM -free survival with #RadioTherapy

#CancerRes 2022
aacrjournals.org/cancerres/ar...

Charles I: Downfall of a King on the BBC iPlayer #SKCM