Re-infection with #SARS-CoV-2 is associated with increased #antibody breadth and potency against diverse #sarbecovirus strains

Re-infection with #SARS-CoV-2 is associated with increased #antibody breadth and potency against diverse #sarbecovirus strains, etidiohnew.blogspot.com/2026/02/re-i...

Original post on linuxrocks.online

A new preprint describes a natural bat sarbecovirus carrying an intact furin cleavage site. This demonstrates that polybasic furin cleavage site motifs can arise in situ in wild coronaviruses, undermining claims that the SARS-CoV-2 furin cleavage site is diagnostic of laboratory engineering […]

#Bat #sarbecovirus WIV1-CoV bears an adaptive #mutation that alters #spike dynamics and enhances #ACE2 binding

#Bat #sarbecovirus WIV1-CoV bears an adaptive #mutation that alters #spike dynamics and enhances #ACE2 binding, etidiohnew.blogspot.com/2025/10/bat-...

Mechanisms for cross–neutralisation of diverse bat sarbecoviruses The continuing evolution of SARS–CoV–2 variants of concern, and the increasing spillover potential of sarbecoviruses into the human population presents an important and urgent need to discover cross-r...

And the sister paper from collaborator and good friend Katie Doores ... A deeper dive into how some of these broadly neutralising #sarbecovirus #coronavirus #sars2 #covid antibodies actually work www.biorxiv.org/content/10.1...

Understanding the future risk of bat coronavirus spillover into humans: correlating sarbecovirus receptor usage, host range, and antigenicity. Sarbecoviruses interact with their receptor, angiotensin converting enzyme 2 (ACE2), via the receptor binding domain (RBD) of Spike, the immunodominant target for neutralising antibodies. Understandin...

Our first post on here and it's a doozy 😍🤩. Our epic piece on #sarbecovirus host range. #virology #sars2 #covid #vaccines. Enjoy and please repost. www.biorxiv.org/content/10.1...

Had a great time presenting at #Microbio25, diving into the evolution of sarbecoviruses! These viruses keep us on our toes. Exciting discussions and great science all around! #Virology #Sarbecovirus @microbiologysociety.org