BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis

BMX inhibition reverses #Chemoresistance in #SmallCellLungCancer by stabilizing E2F1 via the ERK1/2-Cyclin D1/CDK4/6 axis, offering a promising strategy to improve therapeutic outcomes in advanced cases.

#STTT #OpenAccess: doi.org/10.1038/s413...

#Proteomic profiling of #SmallCellLungCancer reveals PS1 and PS2 subtypes with distinct #neuroendocrine, metabolic, and immune features, showing prognostic differences and highlighting PS2’s immune cluster as vulnerable to #immunotherapy.

#OpenAccess: doi.org/10.1016/j.ge...

#CancerAdvocacy #PatientVoices #HTA #tarlatamab #PatientExperience #CancerSupport #Imdelltra #SmallCellLungCancer #SCLC #PatientAdvocacy #CaregiverSupport #CancerAwareness #PublicFunding #AccessToCare #LungCancerCanada

#LungCancer #SmallCellLungCancer #CancerEducation

📝Access the full Small Cell Lung Cancer Quiz here: bit.ly/SCLC_ONCO_IQ_X

🧠This week’s ONCO-IQ Quiz challenge is on Small Cell Lung Cancer. Comment the right answer below.👇🏻

#SCLC #SmallCellLungCancer #LungCancer #MedTwitter #OncTwitter #MedEd #ONCOIQ

Serial #CirculatingTumorDNA profiling can stratify risk and predict benefit from consolidation #immunotherapy in limited-stage #SmallCellLungCancer, identifying high-risk patients who gain significant survival advantage from #CCRT plus PD-1 blockade.

#STTT: doi.org/10.1038/s413...

Inflammation fuels small cell lung cancer – one of the most aggressive forms of cancer – BioNews Central Researchers have discovered a novel mechanism underlying the highly aggressive nature of small cell lung cancer (SCLC). ...

Researchers have discovered a novel mechanism underlying the highly aggressive nature of #SmallCellLungCancer (#SCLC).
#Inflammation #LungCancer

🫁  #VHIO hosted the 1st @sosclc-aecc.bsky.social Annual Symposium — bringing together researchers, clinicians, and patient representatives to advance progress in #SmallCellLungCancer research.

➡️ https://linke.to/SOSCLC-AECCVHIO

#AECCVHIO #PulmónVHIO
@cerca.cat @mmalumbres.bsky.social

🎯 The 1st #SOSCLCAECC Annual Symposium kicks off today at #VHIO ‼️ 

Two days to strengthen Spain’s national network in #SmallCellLungCancer — fostering dialogue, knowledge exchange, and collaboration among experts and trainees.

🤝 Co-coordinated by Hospital Universitario 12 de Octubre & #VHIO

Stay tuned for its release! 💙

#LungCancer #PatientEducation #Oncology #CancerAwareness #SmallCellLungCancer

Researchers at @pmresearch-uhn.bsky.social have identified a potential new target to enhance radiation therapy for #SmallCellLungCancer.

Blocking HDAC3 protein function makes cancer cells more sensitive to radiation.

🔗 Read more: www.uhnresearch.ca/news/increas...

Lung cancer cells in the brain form electrical connections with neurons that spur tumor growth – BioNews Central Small-cell lung cancer cells that metastasize to the brain form functional electrical connections with neurons, and the resulting electrical signals strongly promote tumor growth. ...

#SmallCellLungCancer cells that metastasize to the #brain form functional electrical connections with #neurons, and the resulting #ElectricalSignals strongly promote #TumorGrowth.
#LungCancer #BrainMetastasis

Wendy Brooks talks about promising new therapies for small cell lung cancer, including bite therapy and targeted antibody drug conjugates. These treatments bring new hope by focusing directly on cancer cells. Learn more: buff.ly/2zzdc5p

#LivingWithLungCancer #SmallCellLungCancer

New Strategy for Small Cell Lung Cancer Treatment Emerges from Dana-Farber Science | Dana-Farber Cancer Institute New research from Dana-Farber Cancer Institute shows that a new class of drug results in cancer cell death in cancers, such as small cell lung cancer, with a disabled quality control cell cycle checkp...

New hope for #SmallCellLungCancer.
Dana-Farber scientists reveal a new strategy using direct cyclin inhibitors; backed by preclinical evidence & ready for clinical trials. A fresh path in tackling aggressive cancers.
#CancerResearch #LungCancer #TCSC #DanaFarber

www.dana-farber.org/newsroom/new...

Lung Cancer Foundation of America continues to create grants for researchers unlocking potential treatments for lung cancer, including small cell lung cancer. Tune into our podcast that touches on the latest technology in SCLC treatment: buff.ly/gctJHGG #CancerResearch #SmallCellLungCancer

Dr. Triparna Sen highlights the importance of biomarker-driven strategies in small cell lung cancer research. These advancements are paving the way for more targeted treatments.
#LungCancer #SmallCellLungCancer

Watch the full video here: buff.ly/8Cgv6Qf

FDA grants Orphan Drug Designation to Ariceum cancer therapy - PharmaTimes Designation follows promising preclinical data and FDA clearance

#OrphanDrugDesignation #ODD #AriceumTherapeutics #systemictargetedradiotherapy#radiopharmaceuticalcancertherapy #radiopharmaceutical #225Acsatoreotide #SmallCellLungCancer #SCLC #SCLCpatients #SANTANA225clinialtrial #theranosticpair #targetedradionuclidetreatment
pharmatimes.com/news/fda-gra...

Bob Uecker Dies at 90 from Small-Cell Lung Cancer - OncoDaily Bob Uecker Dies at 90 from Small-Cell Lung Cancer, Mr Baseball, Lung cancer awarennes, Bob Uecker career, Bob Uecker awards, Uecker 90

Bob Uecker Dies at 90 from Small-Cell Lung Cancer

oncodaily.com/stories/cele...

#Baseball #Cancer #LungCancer #LungCancerAwareness #OncoDaily #Oncology #SCLC #SmallCellLungCancer #Medicine #Health

Amgen’s lung cancer treatment gets conditional approval - PharmaTimes IMDYLLTRA offers new hope for patients with extensive-stage small cell lung cancer

#oncology #lungcancer @amgen.bsky.social #lungcancertreatment #IMDYLLTRA #tarlatamab #extensivestagesmallcelllungcancer #ESSCLC #ESSCLCpatients #UK #MHRA #conditionalmarketingauthorisation #Smallcelllungcancer #SCLC #DeLLphi301study #objectiveresponserate
pharmatimes.com/news/amgens-...

Imfinzi Revolutionizes Treatment for Limited-Stage Small Cell Lung Cancer with FDA Approval AstraZeneca's groundbreaking immunotherapy, Imfinzi (durvalumab), has been granted FDA approval for the treatment of adult patients with limited-stage small cell lung cancer (LS-SCLC), marking a signi...

www.linkedin.com/pulse/imfinz...

Imfinzi Revolutionizes Treatment for Limited-Stage Small Cell Lung Cancer with FDA Approval

kstrategyand.com

#Imfinzi #AstraZeneca #LungCancer #SmallCellLungCancer #SCLC #FDAApproval #MedicalBreakthrough #Humanteconomy #Humantec #KStrategyand

FDA approves durvalumab for limited-stage small cell lung cancer - OncoDaily FDA approves durvalumab for limited-stage small cell lung cancer / Australian Therapeutic Goods Administration, Brazilian Health Regulatory Agency, Byoung

FDA approves durvalumab for limited-stage small cell lung cancer

oncodaily.com/blog/fda-198...

fda.gov

#Cancer #Durvalumab #EuropeanMedicinesAgency #FDA #Health #OncoDaily #Oncology #SmallCellLungCancer

💥COOL! Prof #Renier_Brentjens @roswellpark.bsky.social #Cancer #Center/ #CAR_T #immunotherapy dual targeting of antigens incr efficacy in mice w/ #SCLC #Bridge2024 @sitcancer.bsky.social @egfrpositiveuk.bsky.social @alkpositiveuk.bsky.social @cruk-mi.bsky.social #SmallCellLungCancer #FinishCancer

COOL! Prof #Renier_Brentjens @roswellpark.bsky.social #Cancer #Center/ #CAR_T #immunotherapy to #DLL3 using scFvs /SC16.8 cures #SCLC in mice without #lymphodepletion #Bridge2024 @sitcancer.bsky.social @egfrpositiveuk.bsky.social @alkpositiveuk.bsky.social @cruk-mi.bsky.social #SmallCellLungCancer