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SPINAL CORD
— Anatomy, Structure & Functions ...
— Central Nervous System Connection Pathway ...
#spinalcord #iprkashmishra #nervoussystem #spinalanatomy #spinalhealth

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28 THE CENTRAL NERVOUS SYSTEM, BRAIN AND SPINAL CORD EXPLAINED #50LAM_ANATOMY_ENG
28 THE CENTRAL NERVOUS SYSTEM, BRAIN AND SPINAL CORD EXPLAINED #50LAM_ANATOMY_ENG YouTube video by 50 LIKE A MACHINE

28 THE CENTRAL NERVOUS SYSTEM, BRAIN AND SPINAL CORD EXPLAINED #50LAM_ANATOMY_ENG
youtube.com/shorts/TfCb7...
#centralnervoussystem #brain #spinalcord #cnsanatomy #neuroscience #nervoussystem #cerebrum #cerebellum #brainstem #cerebrospinalfluid

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11 THE VERTEBRAL COLUMN AND SPINAL ANATOMY, STRUCTURE AND FUNCTION #50LAM_ANATOMY_ENG
11 THE VERTEBRAL COLUMN AND SPINAL ANATOMY, STRUCTURE AND FUNCTION #50LAM_ANATOMY_ENG YouTube video by 50 LIKE A MACHINE

11 THE VERTEBRAL COLUMN AND SPINAL ANATOMY, STRUCTURE AND FUNCTION #50LAM_ANATOMY_ENG
youtube.com/shorts/MJp3C...
#Anatomy #SpinalColumn #VertebralColumn #SpinalCord #SkeletalSystem #CervicalSpine #ThoracicSpine #LumbarSpine #Sacrum #Coccyx

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A huge thanks to all our colleagues for their feedback and support throughout this journey! 🥂✨

#DevelopmentalBiology #Neuroscience #SpinalCord #StemCells #ScienceAdvances

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KI researchers have created a detailed map showing how genetic activity is controlled in individual cells of the adult human #brain and #spinalcord. Oligodendroglia retain an epigenetic memory of developmental programs long after these genes are no longer active 🧪 news.ki.se/new-map-reve...

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NEWS
You Might Have Missed

@spinalcordinjuryrecovery
@spinalcordinjuries
@spinalcordinjuryconnection
@spinal_cord_injuries
#spinalcord #health #wellness #mmj #mmjpatient #mmjcommunity #community #healthcare #selfcare #patientcare #care

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03-03-25 News Nibble Some good news about spinal cord repair! https://www.youtube.com/@NicksNews-SBS https://www.facebook.com/NicksNews.SBS/ https://www.instagram.com/nicksnews_sbs #goodnews #NicksNew... TikTok video by nicksnews_sbs

Three times a week we release tiny bits of good news that help remind us that not everything is trash. I'll try to be more consistent about sharing these with you all. They really do help when everything feels heavy
www.tiktok.com/@nicksnews_s...
#goodnews #spinalcord #health #medicine #healing

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Coming Home to Heal Traveling the path of body grief isn’t weakness. We can deeply embody our life as it is, finding our way to self-compassion and body trust.

"7 years later, following a car crash that resulted in a #SpinalCord Fracture, Burch again returned to #work ..“I built my fortress of #denial. And then, of course, the #body gives up. You can’t keep going like that.”": buff.ly/RHLtCgR

via MindfulOnline
#disability #healing #SelfCompassion #spoonie

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Mini Lab-Grown Spinal Cords Test Repair Therapy. Regenerative nanomedicine researchers now report the successful regrowth of spinal cord nerve fibers while minimizing the interference of scar tissue. #spinalcord #paraplegia #quadraplegia #peptides #organoids

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Helping Spinal Cords Heal. The neural support cell, the astrocyte, plays a crucial role in spinal cord healing following injury. #spinalcord #injury #astrocyte #ccn1

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Development of a PTEN-siRNA activated scaffold to promote axonal regrowth following spinal cord injury

Our latest publication in Bioactive Materials showing how scaffold based #genedelivery can be applied to #spinalcord with a PTEN-siRNA activated scaffold promoting axonal regrowth
www.sciencedirect.com/science/arti...

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Paralysis treatment heals lab-grown human spinal cord organoids New therapy triggers neurite growth, reduces scarring in injured organoids

#Paralysis treatment heals #labgrown #human #spinalcord organoids

news.northwestern.edu/stories/2026...

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Confirming clear spinal fluid before injection of exosome for Lumbar puncture for the treatment of low back pain associated with spinal disc wear #spinalcord #lowbackpain #glorywellnessclinics #stemcells

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Divergent #TDP43-regulated and TDP43-independent cryptic splicing in the cortex and #spinalcord

Dwight F. Newton, Rena Yang, Johnny Gutierrez...Brad A. Friedman #ALS #AmyotrophicLateralSclerosis #FrontotemporalDementia

link.springer.com/article/10.1...

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Vitamin B12, Cobalamin, Deficiency, Symptoms, Anemia, Nerve Damage, Malabsorption B12 is essential for the production of red blood cells and aids in the maintenance of a healthy nervous system. B12 deficiency damages the brain, spinal cord, peripheral nerves, and nerves of the eye.

Did you know a #VitaminB12 deficiency can mimic #dementia or #psychosis among other symptoms?

"B12 deficiency damages the #brain, #spinalcord, peripheral #nerves, and nerves of the #eye. It is a crucial element in the construction of #DNA."

Learn more:
b12awareness.org/vitamin-b12-...

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Potent gummies for days that are especially “triggering,” to my aura.
55.6mgs THC 🌞 💪🏼
#FuegoMangoLuckyChews
#SweetSpotDispensary
#MedicalCannabis 🌿
#SpinalCord #NerveDamage
#ZeroAddiction

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Recording setup and data analysis. Top left panel: Schematic of the position of the electrodes to record EEG (white), ESI (black), ECG (red), somatosensory activity at Erb’s points (green), and the positions of Common Mode Sense (CMS) (blue) and DRL (orange) electrodes. Note that Erb and ECG electrodes were placed on the chest, while ESI electrodes were placed on the back. Top right and bottom panels: Flowchart describing the analysis procedure. (1 and 2) Raw ESI signals are first re-referenced to the most caudal dorsal electrode (S64). (3) The artifact caused by the electrical stimulation of the median nerve is removed by linear interpolation. (4) The ECG is used to identify ESI time windows contaminated by the QRS complex (orange). This allows subsequent selection of ESI time windows to retain. (5) These time windows are epoched around the somatosensory stimulus. (6) An amplitude-based threshold is used to identify and remove artifactual epochs (red). (7) Resulting artifact-free epochs are averaged across stimuli of each block. Subject-level average waveforms are subsequently averaged across participants. (8) Images of the spatial distribution of spinal cord activity are calculated by spline interpolation across ESI electrodes. The figurine depicts spinal cord activity at the latency of the N13 wave.

Recording setup and data analysis. Top left panel: Schematic of the position of the electrodes to record EEG (white), ESI (black), ECG (red), somatosensory activity at Erb’s points (green), and the positions of Common Mode Sense (CMS) (blue) and DRL (orange) electrodes. Note that Erb and ECG electrodes were placed on the chest, while ESI electrodes were placed on the back. Top right and bottom panels: Flowchart describing the analysis procedure. (1 and 2) Raw ESI signals are first re-referenced to the most caudal dorsal electrode (S64). (3) The artifact caused by the electrical stimulation of the median nerve is removed by linear interpolation. (4) The ECG is used to identify ESI time windows contaminated by the QRS complex (orange). This allows subsequent selection of ESI time windows to retain. (5) These time windows are epoched around the somatosensory stimulus. (6) An amplitude-based threshold is used to identify and remove artifactual epochs (red). (7) Resulting artifact-free epochs are averaged across stimuli of each block. Subject-level average waveforms are subsequently averaged across participants. (8) Images of the spatial distribution of spinal cord activity are calculated by spline interpolation across ESI electrodes. The figurine depicts spinal cord activity at the latency of the N13 wave.

The role of the #SpinalCord in relaying brain-body signals has been hard to study noninvasively. @giuliog.bsky.social &co develop Electrical Spinal Imaging (ESI), enabling high-resolution, noninvasive recordings, revealing how #attention modulates spinal activity @plosbiology.org 🧪 plos.io/3MswZOf

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Recording setup and data analysis. Top left panel: Schematic of the position of the electrodes to record EEG (white), ESI (black), ECG (red), somatosensory activity at Erb’s points (green), and the positions of Common Mode Sense (CMS) (blue) and DRL (orange) electrodes. Note that Erb and ECG electrodes were placed on the chest, while ESI electrodes were placed on the back. Top right and bottom panels: Flowchart describing the analysis procedure. (1 and 2) Raw ESI signals are first re-referenced to the most caudal dorsal electrode (S64). (3) The artifact caused by the electrical stimulation of the median nerve is removed by linear interpolation. (4) The ECG is used to identify ESI time windows contaminated by the QRS complex (orange). This allows subsequent selection of ESI time windows to retain. (5) These time windows are epoched around the somatosensory stimulus. (6) An amplitude-based threshold is used to identify and remove artifactual epochs (red). (7) Resulting artifact-free epochs are averaged across stimuli of each block. Subject-level average waveforms are subsequently averaged across participants. (8) Images of the spatial distribution of spinal cord activity are calculated by spline interpolation across ESI electrodes. The figurine depicts spinal cord activity at the latency of the N13 wave.

Recording setup and data analysis. Top left panel: Schematic of the position of the electrodes to record EEG (white), ESI (black), ECG (red), somatosensory activity at Erb’s points (green), and the positions of Common Mode Sense (CMS) (blue) and DRL (orange) electrodes. Note that Erb and ECG electrodes were placed on the chest, while ESI electrodes were placed on the back. Top right and bottom panels: Flowchart describing the analysis procedure. (1 and 2) Raw ESI signals are first re-referenced to the most caudal dorsal electrode (S64). (3) The artifact caused by the electrical stimulation of the median nerve is removed by linear interpolation. (4) The ECG is used to identify ESI time windows contaminated by the QRS complex (orange). This allows subsequent selection of ESI time windows to retain. (5) These time windows are epoched around the somatosensory stimulus. (6) An amplitude-based threshold is used to identify and remove artifactual epochs (red). (7) Resulting artifact-free epochs are averaged across stimuli of each block. Subject-level average waveforms are subsequently averaged across participants. (8) Images of the spatial distribution of spinal cord activity are calculated by spline interpolation across ESI electrodes. The figurine depicts spinal cord activity at the latency of the N13 wave.

The role of the #SpinalCord in relaying brain-body signals has been hard to study noninvasively. @giuliog.bsky.social &co develop Electrical Spinal Imaging (ESI), enabling high-resolution, noninvasive recordings, revealing how #attention modulates spinal activity @plosbiology.org 🧪 plos.io/3MswZOf

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Recording setup and data analysis. Top left panel: Schematic of the position of the electrodes to record EEG (white), ESI (black), ECG (red), somatosensory activity at Erb’s points (green), and the positions of Common Mode Sense (CMS) (blue) and DRL (orange) electrodes. Note that Erb and ECG electrodes were placed on the chest, while ESI electrodes were placed on the back. Top right and bottom panels: Flowchart describing the analysis procedure. (1 and 2) Raw ESI signals are first re-referenced to the most caudal dorsal electrode (S64). (3) The artifact caused by the electrical stimulation of the median nerve is removed by linear interpolation. (4) The ECG is used to identify ESI time windows contaminated by the QRS complex (orange). This allows subsequent selection of ESI time windows to retain. (5) These time windows are epoched around the somatosensory stimulus. (6) An amplitude-based threshold is used to identify and remove artifactual epochs (red). (7) Resulting artifact-free epochs are averaged across stimuli of each block. Subject-level average waveforms are subsequently averaged across participants. (8) Images of the spatial distribution of spinal cord activity are calculated by spline interpolation across ESI electrodes. The figurine depicts spinal cord activity at the latency of the N13 wave.

Recording setup and data analysis. Top left panel: Schematic of the position of the electrodes to record EEG (white), ESI (black), ECG (red), somatosensory activity at Erb’s points (green), and the positions of Common Mode Sense (CMS) (blue) and DRL (orange) electrodes. Note that Erb and ECG electrodes were placed on the chest, while ESI electrodes were placed on the back. Top right and bottom panels: Flowchart describing the analysis procedure. (1 and 2) Raw ESI signals are first re-referenced to the most caudal dorsal electrode (S64). (3) The artifact caused by the electrical stimulation of the median nerve is removed by linear interpolation. (4) The ECG is used to identify ESI time windows contaminated by the QRS complex (orange). This allows subsequent selection of ESI time windows to retain. (5) These time windows are epoched around the somatosensory stimulus. (6) An amplitude-based threshold is used to identify and remove artifactual epochs (red). (7) Resulting artifact-free epochs are averaged across stimuli of each block. Subject-level average waveforms are subsequently averaged across participants. (8) Images of the spatial distribution of spinal cord activity are calculated by spline interpolation across ESI electrodes. The figurine depicts spinal cord activity at the latency of the N13 wave.

The role of the #SpinalCord in relaying brain-body signals has been hard to study noninvasively. @giuliog.bsky.social &co develop Electrical Spinal Imaging (ESI), enabling high-resolution, noninvasive recordings, revealing how #attention modulates spinal activity @plosbiology.org 🧪 plos.io/3MswZOf

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New research from NYU Grossman School of Medicine: Stem cell-based approach to identify important regulatory transcription factors in various pathways during mammalian cell differentiation. #development #spinalcord https://ow.ly/i55H50Xve5V

ISSCR | The Gairdner Foundation | SickKids Foundation

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Let's remind that "what is lost is lost in #MS" ☹️😤

#TimeIsBrain & #SpinalCord
#MultipleSclerosis
#TreatHard with high efficacy DMT (disease modifying treatment)

#disability
#Chronicillness
#MSHasNoCure
#MS is a progressive disease

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What if leg weakness is the first sign of lung cancer? A 54-year-old man’s spinal MRI revealed intramedullary metastases, leading to the diagnosis of lung adenocarcinoma.

Read more: www.cureus.com/articles/415...

#Cureus #Neurology #Oncology #LungCancer #SpinalCord #MedSky

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BMP signaling-dependent dorsal-to-ventral gradient of PAX3/7 transcriptional activity revealed by the P34::tk::LacZ reporter. Left: expression patterns of neural progenitor (NP) and interneuron (IN) TF markers in the developing spinal cord. Right: Immunostaining for β-galactosidase (β-gal; red/grey), GFP (blue/grey) and either OLIG3 (green/grey) or pSMAD1/5/9 (green/grey) on transverse sections of E9.0 (bottom) and E9.5 (top) P34::tk::LacZ; Pax3+/GFP spinal cords at brachial level. Black and white panels show magnified views of the boxed region.

BMP signaling-dependent dorsal-to-ventral gradient of PAX3/7 transcriptional activity revealed by the P34::tk::LacZ reporter. Left: expression patterns of neural progenitor (NP) and interneuron (IN) TF markers in the developing spinal cord. Right: Immunostaining for β-galactosidase (β-gal; red/grey), GFP (blue/grey) and either OLIG3 (green/grey) or pSMAD1/5/9 (green/grey) on transverse sections of E9.0 (bottom) and E9.5 (top) P34::tk::LacZ; Pax3+/GFP spinal cords at brachial level. Black and white panels show magnified views of the boxed region.

How do pleiotropic TFs generate organized diversity in developing tissues? @spinalorga.bsky.social shows that PAX3 & PAX7 organize #SpinalCord by acting as both repressors & pioneer activators, regulated by #morphogens to ensure precise neural subtype specification @plosbiology.org 🧪 plos.io/4qumsla

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BMP signaling-dependent dorsal-to-ventral gradient of PAX3/7 transcriptional activity revealed by the P34::tk::LacZ reporter. Left: expression patterns of neural progenitor (NP) and interneuron (IN) TF markers in the developing spinal cord. Right: Immunostaining for β-galactosidase (β-gal; red/grey), GFP (blue/grey) and either OLIG3 (green/grey) or pSMAD1/5/9 (green/grey) on transverse sections of E9.0 (bottom) and E9.5 (top) P34::tk::LacZ; Pax3+/GFP spinal cords at brachial level. Black and white panels show magnified views of the boxed region.

BMP signaling-dependent dorsal-to-ventral gradient of PAX3/7 transcriptional activity revealed by the P34::tk::LacZ reporter. Left: expression patterns of neural progenitor (NP) and interneuron (IN) TF markers in the developing spinal cord. Right: Immunostaining for β-galactosidase (β-gal; red/grey), GFP (blue/grey) and either OLIG3 (green/grey) or pSMAD1/5/9 (green/grey) on transverse sections of E9.0 (bottom) and E9.5 (top) P34::tk::LacZ; Pax3+/GFP spinal cords at brachial level. Black and white panels show magnified views of the boxed region.

How do pleiotropic TFs generate organized diversity in developing tissues? @spinalorga.bsky.social shows that PAX3 & PAX7 organize #SpinalCord by acting as both repressors & pioneer activators, regulated by #morphogens to ensure precise neural subtype specification @plosbiology.org 🧪 plos.io/4qumsla

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BMP signaling-dependent dorsal-to-ventral gradient of PAX3/7 transcriptional activity revealed by the P34::tk::LacZ reporter. Left: expression patterns of neural progenitor (NP) and interneuron (IN) TF markers in the developing spinal cord. Right: Immunostaining for β-galactosidase (β-gal; red/grey), GFP (blue/grey) and either OLIG3 (green/grey) or pSMAD1/5/9 (green/grey) on transverse sections of E9.0 (bottom) and E9.5 (top) P34::tk::LacZ; Pax3+/GFP spinal cords at brachial level. Black and white panels show magnified views of the boxed region.

BMP signaling-dependent dorsal-to-ventral gradient of PAX3/7 transcriptional activity revealed by the P34::tk::LacZ reporter. Left: expression patterns of neural progenitor (NP) and interneuron (IN) TF markers in the developing spinal cord. Right: Immunostaining for β-galactosidase (β-gal; red/grey), GFP (blue/grey) and either OLIG3 (green/grey) or pSMAD1/5/9 (green/grey) on transverse sections of E9.0 (bottom) and E9.5 (top) P34::tk::LacZ; Pax3+/GFP spinal cords at brachial level. Black and white panels show magnified views of the boxed region.

How do pleiotropic TFs generate organized diversity in developing tissues? @spinalorga.bsky.social shows that PAX3 & PAX7 organize #SpinalCord by acting as both repressors & pioneer activators, regulated by #morphogens to ensure precise neural subtype specification @plosbiology.org 🧪 plos.io/4qumsla

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SpIC3D imaging for spinal in situ contrast 3D visualization Liang et al. develop SpIC3D, a multi-contrast spinal imaging pipeline that preserves intact anatomical fidelity in ex vivo specimens, across spinal levels and species, including humans. SpIC3D enables...

Taxpayer funding fuels breakthroughs! 💡 Univ of Pittsburgh Neural Engineering Cross-Translation program's (NExT’s) SpIC3D creates a 3D spinal cord map for safer therapies, faster research, and fewer animals, maximizing every $.
🔗 www.cell.com/cell-reports...
#UPNExT #NIH #SpinalCord #MedicalImaging

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#quotes #books #booksky #excerpts #citations #neuroplasticity #costandi ##brain #pain #spinalcord #neurobiology #neurology #chronic #nerves

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⚠️REALLY - We NOW have created MINI SPINAL CORDS⚠️ #minispinalcords #spinalcord #backpain #backinjury #newtech #toilettimetv

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Polylaminin: All About the Drug That Repairs Spinal Cord Injuries A protein from the placenta repairs the spinal cord. It works in dogs. In humans? Too soon to know for sure.

Polilaminina: a protein from placenta repairs spinal cord injuries in paralyzed dogs. Promising animal trials show motor recovery, but human clinical approval remains years away.

#futuroprossimo #spinalcord

en.futuroprossimo.it/2025/09/poli...

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‘Game changer’ implant helps stabilize blood pressure in patients with spinal cord injuries Research led by teams at several universities worldwide, including the University of Calgary, shows that a new implantable system on patients’ spines can restore blood pressure balance after a spinal ...

Canadian designed implant helps stabilize blood pressure in patients with #spinalcord injuries
www.ctvnews.ca/health/artic... @ctvnews-mirror.bsky.social
@ucalgary.bsky.social

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