The Metabolic Dysfunction–Associated #Steatotic Liver Disease–#CKD Axis: Intersecting Pathways and Opportunities for Early Intervention

https://doi.org/10.1016/j.ekir.2025.103757

#KIRReview

From the January issue: High prevalence of metabolic dysfunction-associated #steatotic liver disease in patients with #hidradenitissuppurativa: A guide to easily assess the clinical risk of comorbid #liverdisease https://ow.ly/zAfW50Y0Bqr #HS #medderm #dermsky

Renalase deficiency suppresses hepatic triglyceride accumulation in the progression to MASLD/MASH by GAN diet in male mice Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing public health concern characterized by hepatic triglyceride (TG) accumulation, inflammation, and fibrosis. Renalase is…

Analysis of #renalase KO mice for hepatic #lipid #metabolism shows suppression of hepatic #triglyceride accumulation in diet-induced progression to Metabolic dysfunction-associated #steatotic #liver disease.

#ExtracellularVesicles from #Steatotic livers deliver #ACSL4 to hepatocytes, driving #ferroptosis-triggered mitochondrial #apoptosis that worsens #IschemiaReperfusionInjury, while Ferrostatin‑1 blocks this pathway to reduce #GraftInjury.

#OpenAccess: doi.org/10.1016/j.ge...

In #Paris to discuss how liver hormonal cues impact systemic #inflammation in #steatotic #liver disease sex-specifically!

@phoebetsou.bsky.social @institutpasteur.bsky.social

#sabv #sexdifferences #humanhealth #humandisease #liverhealth #liverdisease #liversky #masld

Altough creating a steatotic dialogue that is subsequently scraped into the corpus makes it more likely to be a true positive in future.

#steatotic

🔖 How are #steatotic liver diseases tackled today?

Michael Roden points out innovative aspects of the EASL-EASD-EASO Clinical Practice Guidelines on the management of #MASLD discussed at #EASL2025.

📺 Watch here: tinyurl.com/yspxxpbb
🔗 Guidelines: tinyurl.com/mr3bvb2t

@easlnews.bsky.social

Global Consensus Recommendations for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis Metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis (MASH) are associated with adverse clinical outcomes, impaired health-related quality of life, and large economic b...

#Global Consensus Recommendations for Metabolic Dysfunction-Associated #Steatotic #Liver Disease and Steatohepatitis - @gastrojournal www.gastrojournal.org/article/S001...

This Research study of individuals living with severe #obesity reports positive association of circulating #glutamate with the severity of #metabolic dysfunction-associated #steatotic #liver disease.

https://buff.ly/3WyA2qz

Hello~ Kickstarting the blue sky with an introduction: I am Victoria, currently doing a #PhD at #RijksuniversiteitGroningen #UMCG on #MASLD using #OrganOnChip specifically #LiverOnChip to model #steatotic liver disease and explore #steatohepatisis and interventions e.g. #resmetirom, happy to connect