On-site at #GU26, sharing insights on advancing first-line care in locally advanced/metastatic #urothelial #carcinoma! Developed with partners LUGPA & @bladdercancerus.bsky.social, this initiative blends clinician & patient advocacy perspectives to drive community-informed education. bit.ly/4rHAgcw
MAFB and #CEBPA promote #urothelial growth, and their reduced expression in #hypospadias reveals a pathogenic mechanism whereby MAFB knockdown suppresses CEBPA, inhibits #Wntβcatenin signaling, arrests the #cellcycle, and induces #apoptosis.
#OpenAccess: doi.org/10.1016/j.ge...
This study shows that MAFB suppresses #Urothelial #CellGrowth by downregulating #CEBPA and inhibiting #Wnt/#β-catenin signalling, providing new insights into the #Genetic mechanisms underlying #Hypospadias. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
#UTI are the most common bacterial infections in humans. Konesan et al. develop an ex-vivo UPEC-infected porcine bladder model 🧫 to asses #urothelial physiology in the presence/absence of #NonAntibiotic agents 💊. Read more: buff.ly/fb5xYAV #PathogDis #Cranberry #D-Mannose
Looking forward to #ASCOGU25
#Prostate: Combos w/ iPARP- and Lu- , EZH2
#Urothelial: Updates, HER-2, FGFR3, and high-risk UTUC
#Renal: Updates, UO3B, KIM-1, HIF-2 inh and MET inh
#Testicular: RPLND advanced Seminoma
#Penile: IO-chemo for advanced Ca
@rickyfrazer1.bsky.social @jmcgrane.bsky.social
#Genitourinary #Oncology #GUonc #GUoncol #GUoncology #ProstateCancer #KidneyCancer #Urothelial #BladderCancer #PenileCancer #TesticularCancer #pcsm #kcsm #blcsm #tcsm #Medsky #Oncsky #Medtwitter
go.bsky.app/DtoXvaD
Last week, Prof Tom Powles gave this year’s prize lecture at @qmbci.bsky.social, in memory of Gordon Hamilton-Fairley. It was a fascinating overview of his research into treatment combinations for #urothelial cancer, set in the context of drug development worldwide.
Innovative therapies in GU cancers: Promising targets in #Urothelial and #Kidney cancer.- BL-B01D1: A bispecific ADC (EGFR/HER3) with a 40% response rate in advanced urothelial cancer.
- NKT2152: A HIF2a inhibitor for RCC, showing promise but with toxicity challenges > bit.ly/3OUcvfe
Cisplatin- or Carboplatin-Based Chemotherapy Plus Pembrolizumab in Advanced #Urothelial #Cancer: Exploratory Analysis From the Phase 3 KEYNOTE-361 Study www.sciencedirect.com/science/arti... #hvhebron #onco
Association of Tumor Mutational Burden and PD-L1 with the Efficacy of Pembrolizumab with or without Chemotherapy versus Chemotherapy in Advanced #Urothelial #Carcinoma scientiasalut.gencat.cat/handle/11351... #ScientiaVH
85 people in here now, and growing - come and join us!
#Genitourinary #Oncology #GUonc #GUoncol #GUoncology #ProstateCancer #KidneyCancer #Urothelial #BladderCancer #PenileCancer #TesticularCancer #pcsm #kcsm #blcsm #tcsm #Medsky #Oncsky #Medtwitter
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66 names on this list now and growing every day - jump on!
go.bsky.app/DtoXvaD
#Genitourinary #Oncology #GUonc #GUoncology #ProstateCancer #KidneyCancer #Urothelial #BladderCancer #PenileCancer #TesticularCancer #pcsm #kcsm #blcsm #tcsm #Medsky #Medtwitter
Bye dark ‘EX’ , hi blue sky.
#Genitourinary #Oncology #GUonc #ProstateCancer #KidneyCancer #Urothelial #BladderCancer #PenileCancer #TesticularCancer
Genitourinary oncology starter pack https://go.bsky.app/DtoXvaD
GU starter pack… started!
Let me know if you want to be added.
go.bsky.app/DtoXvaD
#Genitourinary #Oncology #GUonc #ProstateCancer #KidneyCancer #Urothelial #BladderCancer #PenileCancer #TesticularCancer #pcsm #kcsm #blcsm #tcsm #Medsky #Medtwitter
