Engineering vaccinia virus for improved vaccine vectors opens new routes for next-gen immunization platforms.
doi.org/10.15212/ZOO...
#VacciniaVirus #VaccineVectors #ViralVectors #Immunization

Impaired Cellular Immunity and Cross‐Reactive Humoral Responses to Mpox Virus in HIV‐Infected Individuals Vaccinated with Vaccinia Virus Tiantan Strain This study examines MPXV immunity in PLWH, focusing on smallpox vaccine-induced responses. PLWH with CD4⁺ T-cell counts <500 cells/mm3 showed reduced VTT-IgG, MPXV-IgG, and NAbs, while CD4⁺ T-cell re....

#Article in #MedComm
Impaired Cellular Immunity and Cross-Reactive Humoral Responses to Mpox Virus in HIV-Infected Individuals Vaccinated with Vaccinia Virus Tiantan Strain doi.org/10.1002/mco2...

#HIV #MPXV #HumoralImmuneResponses #MemoryTcell #VacciniaVirus #PLWH

Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector Vaccinia virus is a vital tool in vaccine development, offering cross-protective immunity and serving as a vector for novel vaccines through genetic engineering.

This systematic review delineates the commonly targeted #viral genes for attenuation during #Vacciniavirus (VACV) vector modification and provides an overview of the progress in VACV-vectored #vaccine development.

#OpenAccess: zoonoses-journal.org/index.php/20...

Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector Vaccinia virus is a vital tool in vaccine development, offering cross-protective immunity and serving as a vector for novel vaccines through genetic engineering.

#Vacciniavirus is a vital tool in vaccine development, offering cross-protective immunity and serving as a vector for novel vaccines through genetic engineering.

Read More: tinyurl.com/3ttxrxh3

#Attenuatedvaccinevector #zoonoses #Zoonosis #Zoonotics #Zoonoticdiseases @scienceopen.bsky.social