Rab GTPases as "eat me" signals for selective #autophagy. Yan Zhao discusses new work from Qiming Sun and colleagues (rupress.org/jcb/article/...), which shows how Rab GTPases serve as cues for cargo receptor recruitment, mediating #mitophagy, #lipophagy, and #xenophagy. rupress.org/jcb/article/...

Rab #GTPases are evolutionarily conserved signals mediating selective #autophagy, say Pengwei Zhao, Rui Tian, Dandan Song, Qi Zhu, Xianming Ding, Wei Zou, Qiming Sun and colleagues @ZJU_China: rupress.org/jcb/article/...

#Trafficking #Biochemistry #Mitophagy #Lipophagy #Xenophagy

Spotlight: Yan Zhao previews work from Qiming Sun and colleagues (rupress.org/jcb/article/...), which shows how Rab #GTPases serve as cues for cargo receptor recruitment, mediating #mitophagy, #lipophagy, and #xenophagy. rupress.org/jcb/article/...

#autophagy

This study from the labs of Wei Zou and Qiming Sun @ZJU_China uncovers Rab #GTPases as evolutionarily conserved signals mediating selective #autophagy, targeting damaged #mitochondria, #LipidDroplets, and #pathogens for degradation. rupress.org/jcb/article/...

#mitophagy #lipophagy #xenophagy