Articles in our latest collection focus on the roles of ATG9 and LC3 interacting regions, plus mechanisms of selective #autophagy involving Rab #GTPases, #mitophagy, and #pexophagy. 👉 rupress.org/jcb/collecti...
#GRC

Distinct TRAPP complexes activate Ypt/Rab #GTPases in #secretion and #autophagy. New study from Valeriya Gyurkovska, Nava Segev and colleagues (University of Illinois at Chicago): rupress.org/jcb/article/...

#Biochemistry #Membrane #lipid

Wei Zou & Qiming Sun labs uncover Rab #GTPases as evolutionarily conserved signals mediating selective #autophagy, targeting damaged #mitochondria, #LipidDroplets, and #pathogens for degradation. rupress.org/jcb/article/...

📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#GRC

The mechanism by which the conserved Ypt1/Rab1 #GTPases mediate the beginning of #secretion and #autophagy is unknown. In @jcb.org, Gyurkovska, Segev et al. use in vivo analysis to show that distinct TRAPP complexes activate the yeast Ypt1 in secretion and autophagy rupress.org/jcb/article/...

The mechanism by which the conserved Ypt1/Rab1 #GTPases mediate the beginning of #secretion and #autophagy is unknown. Gyurkovska, Segev et al. use in vivo analysis to show that distinct TRAPP complexes activate the yeast Ypt1 in secretion and autophagy rupress.org/jcb/article/...

Wei Zou & Qiming Sun labs uncover Rab #GTPases as evolutionarily conserved signals mediating selective #autophagy, targeting damaged #mitochondria, #LipidDroplets, and #pathogens for degradation. rupress.org/jcb/article/...

📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#KSAutophagy26

A proximity map of RAB GTPases delineates roles for RAB14 in EARP complex and UHRF1BP1 endosomal recruitments - Communications Biology Proximity labeling proteomics of RAB GTPases identifies an array of neighboring RAB proteins. Functional validation studies reveal links between RAB25 and DENND6A, or between RAB14 and either the EARP...

Research from @jeanlab-uds.bsky.social presenting proximity labelling #proteomics of RAB #GTPases identifies an array of neighbouring RAB proteins and offers a valuable resource for
exploring new functional connections between RAB GTPases and their associated proteins.
www.nature.com/articles/s42...

How do lipid-modified proteins reach the cilium? 🧬 ARL3 and its regulators create spatial control of cargo release—key to signaling & linked to ciliopathies like Joubert syndrome.
Read more: febs.onlinelibrary.wiley.com/doi/10.1002/...
#CellBiology #Cilia #GTPases

Rab #GTPases are evolutionarily conserved signals mediating selective #autophagy, say Pengwei Zhao, Rui Tian, Dandan Song, Qi Zhu, Xianming Ding, Wei Zou, Qiming Sun and colleagues @ZJU_China: rupress.org/jcb/article/...

#Trafficking #Biochemistry #Mitophagy #Lipophagy #Xenophagy

Spotlight: Yan Zhao previews work from Qiming Sun and colleagues (rupress.org/jcb/article/...), which shows how Rab #GTPases serve as cues for cargo receptor recruitment, mediating #mitophagy, #lipophagy, and #xenophagy. rupress.org/jcb/article/...

#autophagy

This study from the labs of Wei Zou and Qiming Sun @ZJU_China uncovers Rab #GTPases as evolutionarily conserved signals mediating selective #autophagy, targeting damaged #mitochondria, #LipidDroplets, and #pathogens for degradation. rupress.org/jcb/article/...

#mitophagy #lipophagy #xenophagy

We got the cover!!! Check out our new story in EMBO J. #endosomes #c.elegans #membranes #GTPases

Maybe a mass migration is what was needed! Hello everybody! My name is Fran and I am an assistant Prof @ Freie Universität Berlin. You will hear all about #membranes #GTPases #superresolution #CRISPR the many joys and struggles of being an #academicmum and an accidental #immunologist