The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1
Researchers show Traf2-and NcK-interacting kinase (TNIK) is reduced in #Epilepsy and #TemporalLobeEpilepsy, and its inhibition with NCB‑0846 delays kindling and reduces #seizure severity, highlighting TNIK as a potential #antiepileptic drug target.
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