This is not at all surprising, and it lends support for other combination therapies that have different mechanisms of action and targets. www.kireports.org/article/S246...
#NephSky #IgANephropathy #IgAN
I hope having my voice amplified by @ajkd.bsky.social will help clinicians and patients.
#IgANephropathy #IgAN #NephSky #MedSky
A little something I wrote about the patient perspective of disease: www.sciencedirect.com/science/auth...
#IgANephropathy #IgAN #NephSky #MedSky
Post-COVID labs are in. Current score:
COVID 0
sibeprenlimab 1
Only numbers out of range at this point are eGFR and SCr (and glucose due to SGLT2i), which is really surprising.
#NephSky #IgANephropathy
#IGAnephropathy took my job my independance and almost my child but it wont take my optimism.
Dose 2 of sibeprenlimab complete. Ask me anything.
#iganephropathy #igan #nephsky
I am now going through another hospital's Transplant program.
Medical bills are piling up, so I'm resharing this information.
My sister is
@sassyscifichick.bsky.social
#Kidney #Transplant #IgANephropathy #CKD #Dialysis #GoFundMe #IgAN #Medical #Bills #Travel #Hospital #Doctors #KidneyTransplant
Currently doing N=1 test of COVID vs. sibeprenlimab, wish me luck.
#IgAN #IgANephropathy #NephSky
This cold has reached man-cold status. Spent all day sleeping off and on on the sofa. Hope it doesn't progress beyond this.
#IgAN #IgANephropathy #NephSky #sibeprenlimab
BHV-1400 is exciting stuff.
#IgAN #IgANephropathy #NephSky
Now I get to see just how effective sibeprenlimab is since my high schooler politely gave me a cold over the weekend. Thankfully, it's not yet evolved to a man cold.
#IgAN #IgANephropathy #NephSky
Update: My insurance company has now approved Filspari after an appeal and fantastic letter of medical necessity from my nephrologist's office. Pay your staff well and tip your servers!
#IgANephropathy #NephSky #IgAN
I started Filspari on 1/24/2025 and was in complete remission by 3/20/2025. Hope this tracks my progression.
#IgANephropathy #IgAN #NephSky
#Medsky🧪 #publichealth @jama.com #IgAnephropathy (IgAN) involves deposition of IgA-containing immune complexes in the glomerular mesangium, triggering glomerular inflammation and scarring.It is the most common cause of immune-mediated glomerular disease worldwide,
jamanetwork.com/journals/jam...
Coming off corticosteroids, even targeted-release formulation budesonide, is no joke. I've lost a pound a day since my last dose on Monday - weight that I didn't even realize I had gained. Fortunately, I haven't had any withdrawal symptoms.
#IgANephropathy #IgAN #NephSky
✔️ First dose of Voyxact (sibeprenlimab) self-administered
✔️ Standard vasovagal response for me
✔️ Glad I did this at my wonderful nephrologist's office
Any questions?
#NephSky #IgANephropathy #IgAN
As excited as I am to have Voyxact approved, I'm equally frustrated that Filspari - a medication I'm ALREADY ON and have had great success with - was denied just because I switched insurance companies. What a cluster.
#IgANephropathy #NephSky #NephJC #IgAN
#MedCase - An extremely rare case of #dermatomyositis concomitant with IgA nephropathy.
Although the possibility of coincidental co-occurrence cannot be ruled out, it seems more likely that a common pathologic mechanism plays a role.
👉 buff.ly/cAAzrpL
#IgANephropathy #RheumSky
I take my first dose of Voyxact (sibeprenlimab) this week and, as always, I remain your human guinea pig. (Maybe lab rodent is a better term?)
#IgANephropathy #NephSky #NephJC #IgAN
221 cases and the tonsillectomy crew looked spotless, remitting like they had a payoff. But when progression came collecting, only three dropped in that group, not enough bodies to hang the surgery. The stats snarl, but in a non-randomized town, bias is the trigger.
doi.org/10.1093/ndt/...
Of course I'm ineligible yet again, but maybe you know somebody who qualifies. This is a phase 3 trial for ravulizumab, a C5 inhibitor.
#NephSky #IgANephropathy #IgAN
Atacicept's BLA has been accepted for Priority Review with a target action date of July 7, 2026.
#NephSky #IgANephropathy #IgAN
Guess I need to eat more yams?
#NephSky #IgAN #IgANephropathy
We caught up with Richard Lafayette after #KidneyWk to discuss ORIGIN-3 results presented at the meeting showing strong proteinuria reduction with ataciceipt in #IgAnephropathy. #nephsky #nephrology #igan www.docwirenews.com/post/atacice...
Kidney Tertiary #LymphoidTissues and Poor #Immunosuppressive Response in #IgANephropathy #IgAN
#VisualAbstract by Elba Medina
www.kireports.org/article/S2468-0249(25)00...
demo of a website about IgA nephropathy, with a level of detail slider for content
Working on a thing, back to coding HTML like it's the late 1990s. #NephSky #IgANephropathy #IgAN #html
I tried to listen to this on our road trip back from Colonial Williamsburg, but the family rejected it even though I promised high production values. "You get to listen to this on your own time." #NephJC #IgAN #IgANephropathy
#Otsuka has claimed #FDA approval for its #IgAnephropathy (IgAN) therapy Voyxact, joining an increasingly crowded market and beating rival Vera Therapeutics to the punch.
www.reuters.com/business/hea... && otsuka-us.com/media/static... && otsuka-us.com/media/static... && www.voyxacthcp.com
#IgAN #IgANephropathy