Development of the Windmill Model for Mapping Older Adults’ Intrinsic Capacity Using Digital Twin Technology: Descriptive Qualitative Study Background: Intrinsic capacity (IC) refers to the sum of the physical and mental capacities of an individual. Conventional IC assessment requires substantial temporal and human resources. Digital twin (DT) technology emerges as a promising solution for efficiently mapping ICs. Objective: This study aims to explore older adults’ perspectives on the DT technology and their perceptions of how it could effectively represent their ICs. Methods: A qualitative study was used. Face-to-face semistructured interviews with 23 older adults were conducted. The interviews were transcribed verbatim and analyzed via content analysis approach. Results: The analysis identified five themes and 16 subthemes: (1) “opt for or not my digital twin,” revealing the older adults’ decisions regarding whether to use DT technology for mapping ICs; (2) “my ideal digital avatar,” describing the older adults’ preferences for personalized digital avatar appearances; (3) “my digital twin maps my intrinsic capacity,” highlighting how multimodal reminders and synchronized avatar changes enhanced their comprehension of ICs; (4) “the benefits my digital twin can deliver,” emphasizing the potential of the DT system to provide feedback services to older adults; (5) “some expectations for my digital twin,” outlining their expectations for DT technology. Based on the above insights, a conceptual model, “windmill” model, was further developed to better understand how to build DTs of older adults and map their ICs. Conclusions: DT technology was a promising tool for mapping ICs of older adults. Furthermore, the “windmill” model provided a framework to build tailored DTs. The findings of this study could provide references to develop DT model to support IC management.

New in JMIR Aging: Development of the Windmill Model for Mapping Older Adults’ Intrinsic Capacity Using Digital Twin Technology: Descriptive Qualitative Study #DigitalTwin #IntrinsicCapacity #AgingResearch #OlderAdults #HealthTech

Frailty is Not Just a Number: The Hidden Barrier to Diabetic Foot Care in Middle Age #ActAgainstAmputation #IntrinsicCapacity diabeticfootonline.c...

Insights on geroscience pre-clinical and clinical trials to promote healthy aging from the Intrinsic Capacity, Frailty and Sarcopenia Research Task Force 2025 The Intrinsic Capacity, Frailty and Sarcopenia Research (ICFSR) Task Force convened in March 2025 to discuss geroscience-oriented pre-clinical and cli…

Insights on #geroscience pre-clinical and clinical #trials to promote healthy #aging from the Intrinsic Capacity, #Frailty and Sarcopenia #Research Task Force 2025

#Ageing #IntrinsicCapacity #Sarcopenia #Science #Biology #Health

www.sciencedirect.com/science/arti...

Multi-trajectories of intrinsic capacity and their impact on incident disability in community-dwelling older adults in Japan The World Health Organization’s intrinsic capacity (IC) framework has shifted focus from functional deficits to preserving abilities in ageing. Howeve…

Multi-trajectories of intrinsic capacity and their impact on incident #disability in community-dwelling older adults in Japan

#Geriatrics #Frailty #IntrinsicCapacity #Ageing #Aging #Health #Care

www.sciencedirect.com/science/arti...

Stanford-led THRIVE coalition secures up to $34.5m from ARPA-H to build FDA-grade intrinsic capacity score predicting 20-year outcomes.

vist.ly/4t6s8

#longevity #intrinsiccapacity #healthspan #preventivemedicine #biomarkers #ARPAH #FDA #agingpolicy

Want to dive a bit deeper yourself? In the US we tend to use the #4M framework: assess mind, mobility, medications, and what matters most to the patient.
The #WHO #IntrinsicCapacity framework of vision, hearing, vitality (nutrition), mobility, cognition, and mental health is another great tool.
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Validate User

A #genome -wide association study identified 10 novel genomic loci associated with #IntrinsicCapacity.

👉Genetic architecture of #IC, laying the foundation for future #research on healthy #aging

#Geriatrics #Genes #Ageing #Health #Genetics

Full-text available here👇
academic.oup.com/biomedgeront...

#IntrinsicCapacity #IntrinsicCapacishit

#IntrinsicCapacity #IntrinsicBS

si la gente se muestra cautelosa hasta el punto de inventar una capacidad intrínseca con el argumento de que la fragilidad está demasiado mal definida y es conceptualmente confusa, esperaría un mayor alboroto (o, más probablemente, una mueca de desprecio)
#IntrinsicCapacity
youtu.be/8eFOygUO7_Q?...

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I’m reframing my practice with the WHO “intrinsic capacity” lens—mobility, cognition, psychological well-being, vitality, sensory—layered onto disease-directed therapy + #intrinsiccapacity
www.nature.com/articles/s41...

A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors - Nature Aging Fuentealba and colleagues build and validate a DNA methylation clock of intrinsic capacity (IC) to bridge resource-intensive clinical assessments of IC with molecular readouts of aging, highlighting s...

A blood-based #epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and #lifestyle factors

"...a validated tool bridging molecular readouts of #aging and clinical assessments of #IC..."

#IntrinsicCapacity #Frailty

www.nature.com/articles/s43...

Excellent output from an #EAMA project to support the teaching and dissemination of #IntrinsicCapacity to medical students.

#Geriatrics #Ageing #Aging #Health #Care #WHO #PHC #PrimaryCare #MedSky

Please use and share the brochure below (English version):
www.eama.eu/Uploads/Inte...

🚨Paper alert
Very happy to share our last work on #IntrinsicCapacity (IC) in dementia with Lewy bodies #DLB (n=154), compared AD (n=644)
👉DLB patients showed lower IC in all domains (locomotion, vitality, psychology, audition), requiring personalized interventions !
🔓 shorturl.at/EfrCX

Very nice paper. Congratulations!

To me, a critical issue in #frailty (and #IntrinsicCapacity) is understanding the limited importance of tools in capturing the condition of interest.

We need to contextualise and be pragmatic. One (tool) will never fit all (globally)

#Geriatrics #Health #Care