Sonic Hedgehog (Shh) signaling potentiates BMP9-induced osteogenic differentiation in mesenchymal stem cells.
#SonicHedgehog #Shh #BMP9 #Osteogenesis #MesenchymalStemCells #BoneRegeneration
www.sciencedirect.com/science/arti...
We are thrilled to announce the release of the newest edition of Int J Fertil Steril, now available for you to explore!
Full issue: www.ijfs.ir/issue_52431_...
#IntJFertilSteril #NewRelease #Research #AcademicPublishing #Sperm #Royaninstitute #RoyalJelly #MesenchymalStemCells #Bioinformatics
Mesenchymal stem cell–mediated renal remodeling in lupus nephritis
MSCs reshape renal inflammation via CXCL10-CXCR3 recruitment and IL4I1 signaling in lupus nephritis.
www.nature.com/articles/s41...
#MesenchymalStemCells #LupusNephritis #RenalDisease #Immunomodulation
Mesenchymal stem cells in treating human diseases
A comprehensive review of MSC mechanisms, immunomodulation, and clinical progress across diverse human diseases.
doi.org/10.1038/s413...
#MesenchymalStemCells #MSC #RegenerativeMedicine
Habiba et al. show that intravenous mesenchymal stem cell therapy is generally safe but warrants further investigation for nervous system and infection-related adverse events.
#OpenAccess in #RMR: doi.org/10.4103/REGE...
#StemCellTherapy #MesenchymalStemCells #RegenerativeMedicine
This review examines #ExtracellularVesicles from oral #MesenchymalStemCells, highlighting their therapeutic potential in oral and systemic diseases, while addressing prospects for clinical translation. @kingscollegelondon.bsky.social
#OpenAccess: doi.org/10.1016/j.ge...
New Joint Research Contract for Eye Disease Treatment Using Stem Cell Derived Culture Medium #Japan #Tokyo #StemCellResearch #EyeDiseaseTreatment #MesenchymalStemCells
This review highlights how #MesenchymalStemCells exert therapeutic effects through #ParacrineSignaling—releasing #GrowthFactors, #cytokines, #chemokines, #ExtracellularMatrix components, & extracellular vesicles shaped by the #microenvironment.
#OpenAccess: doi.org/10.1016/j.ge...
This review outlines the molecular mechanisms, #SignalingPathways, and regulatory factors underlying the therapeutic effects of #MesenchymalStemCells, highlights recent #ClinicalStudies, challenges and future perspectives. #medsky
#STTT #OpenAccess: doi.org/10.1038/s413...
Injectable #hydrogel from Wharton’s jelly matrix combined with #MesenchymalStemCells shows synergistic effects in repairing infarcted myocardium and improving heart function in ischemic rats. Promising advance in #CardiacRegeneration #StemCellTherapy onlinelibrary.wiley.com/doi/10.1002/...
Using integrated #transcriptome and proteome analyses, scientists from @emorydeptofmed.bsky.social identified and validated eight novel non-classical #CDMarkers that help characterize #MesenchymalStemCells and potentially discriminate #iMSCs from other cell types.
#OpenAccess:
buff.ly/vnN9LqA
An Atomic Force Microscopic analysis of Exosomes derived from Tumor Associated pluripotent Mesenchymal Stem Cells.
BANERJEE, H., KULKARNI, T., Bhattacharya, S., BANERJEE, N. N.
Paper
Details
#ExosomeAnalysis #AFMStudy #MesenchymalStemCells
Using integrated #transcriptome and proteome analyses, scientists from @emorydeptofmed.bsky.social identified and validated eight novel non-classical #CDMarkers that help characterize #MesenchymalStemCells and potentially discriminate #iMSCs from other cell types.
#OpenAccess:
buff.ly/oqiiEbd
This study shows that LGR4 augments the osteoblastic potential of BMP9 in #MesenchymalStemCells, and BMP9 may up-regulate LGR4 via activating the mTORC1/Stat3 signal pathway. #osteogenesis #BoneRegeneration #TissueEngineering #medsky
#OpenAccess:
What if we could reprogramme the #TME itself? Cutting-edge research suggests that engineered #mesenchymalstemcells could disrupt this shield – targeting #tumours in a way that finally allows #cancer treatments to do their job.
pharmaphorum.com/oncology/mes...
Published in Bone Research, a team from Zhejiang University School of Medicine has pioneered a stem cell-based system that functions as a "mitochondria factory".
#Energeticmitochondria #Mesenchymalstemcells
Details: doi.org/10.1038/s41413-025-00411-6
Advances in oral mesenchymal stem cell-derived extracellular vesicles in health and disease
This review details the biogenesis, functions, & therapeutic role of oral #MesenchymalStemCells derived #ExtracellularVesicles in oral & systemic diseases, & discusses the challenges & future directions for its clinical translation. #medsky @kingscollegelondon.bsky.social
www.sciencedirect.co...
Meet the Researcher: Dr Cynthia Coleman, Lecturer in Cellular Manufacturing and Therapy in the Regenerative Medicine Institute #GalwayRNAResearchCluster #diabetes #osteopathy #mesenchymalstemcells
Fibrous scaffolds loaded with BMSC-derived apoptotic vesicles promote wound healing by inducing macrophage polarization
This new study demonstrates that apoptotic vesicles derived from bone marrow #MesenchymalStemCells induce macrophage M2 polarization and promote #SkinWoundHealing by targeting the CCL-1 gene through the presence of mmu-miR-21a-5p. #medsky
#OpenAccess: www.sciencedirect.co...
The July Issue of @CellChemBiol is live! Read it here: http://dlvr.it/T9mKhz #smoothened #hedgehog #optogenetics #NaVs #Rho-GTPase #YAP1 #MesenchymalStemCells #K2Pchannels #PROTAC #deubiquitylase #chromatin #PARPinhibitors
Simple and efficient protocol to generate mesenchymal stem cells from human umbilical cord and their differentiation into skeletal muscle lineage using a combo of adhesion modulation & steroid treatment.
#muscle, #MyoTwitter, #mesenchymalstemcells,
