" #Nociceptive #pain is caused by damage to body tissue which is often caused by an external injury..often experienced in joints, muscles, bones, skin, and tendons. This type of pain can be both #AcutePain & #ChronicPain.": buff.ly/KOuFOGG
by @carriekellenberger.bsky.social
#disabled #spoonie
[2024 OPEN ACCESS]
Realization of nociceptive receptors based on Mott memristors
2024 Appl. Phys. Express 17 025001
iopscience.iop.org/article/10.3...
#APEX
#OpenAccess
#Physics
#Mott
#memristor
#receptor
#nociceptive
#LIF
#neurons
Why Does Pain Feel So Different?
Follow me to learn more about: #ChronicPain #Nociceptive #Neuropathic #Nociplastic #neuroplastic #TMS #PainNeuroscience #PainNeuroscienceEducation #PNE #PRT #Neuroplasticity #PainEducation #PainScience
francoishug.bsky.social et al. investigated non-homogeneous distribution of inhibitory inputs among #motor units in response to #nociceptive stimulation at moderate contraction intensity ⚙️ ✍️
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/JP288504
The ACC receives a substantial number of projections from the RSC. Top left: Sagittal view of 3D-reconstructed whole-brain labeling in VISoR imaging (red: DsRed+; green: EGFP+). White dashed boxes represent the regions of ACC and RSC in the brain. Scale bar: 1 mm. a: anterior; d: dorsal. Bottom left: Representative coronal sections of VISoR imaging in the ACC (left panel) and RSC (right panel). Scale bar: 1 mm. Right: A simplified model for supraspinal facilitation of nociception by RSC-ACC excitatory pathway. The peripheral visual, auditory sensory, and somatosensory inputs (the orange lines) are conveyed to the thalamus. Then, the thalamus relays these sensory inputs to the cerebral cortex, such as the ACC and RSC. The ACC, as a high brain center for pain processing, is innervated by not only the subcortical thalamus but also the supracortical RSC (the red arrow lines) to integrate the nociceptive information. The excitatory RSC-ACC pathway probably involves in the combination of pain processing and memory (such as the pain-related contextual memory) by an engram mechanism in the RSC.
Most studies on #nociceptive pathways focus on links between subcortical regions & #SpinalCord, but what about cortico-cortical circuits? This study reveals a pathway from retrosplenial cortex to anterior cingulate #cortex that modulates #pain perception 🧪 @plosbiology.org plos.io/4hcS2iB
The ACC receives a substantial number of projections from the RSC. Top left: Sagittal view of 3D-reconstructed whole-brain labeling in VISoR imaging (red: DsRed+; green: EGFP+). White dashed boxes represent the regions of ACC and RSC in the brain. Scale bar: 1 mm. a: anterior; d: dorsal. Bottom left: Representative coronal sections of VISoR imaging in the ACC (left panel) and RSC (right panel). Scale bar: 1 mm. Right: A simplified model for supraspinal facilitation of nociception by RSC-ACC excitatory pathway. The peripheral visual, auditory sensory, and somatosensory inputs (the orange lines) are conveyed to the thalamus. Then, the thalamus relays these sensory inputs to the cerebral cortex, such as the ACC and RSC. The ACC, as a high brain center for pain processing, is innervated by not only the subcortical thalamus but also the supracortical RSC (the red arrow lines) to integrate the nociceptive information. The excitatory RSC-ACC pathway probably involves in the combination of pain processing and memory (such as the pain-related contextual memory) by an engram mechanism in the RSC.
Most studies on #nociceptive pathways focus on links between subcortical regions & #SpinalCord, but what about cortico-cortical circuits? This study reveals a pathway from retrosplenial cortex to anterior cingulate #cortex that modulates #pain perception 🧪 @plosbiology.org plos.io/4hcS2iB
The ACC receives a substantial number of projections from the RSC. Top left: Sagittal view of 3D-reconstructed whole-brain labeling in VISoR imaging (red: DsRed+; green: EGFP+). White dashed boxes represent the regions of ACC and RSC in the brain. Scale bar: 1 mm. a: anterior; d: dorsal. Bottom left: Representative coronal sections of VISoR imaging in the ACC (left panel) and RSC (right panel). Scale bar: 1 mm. Right: A simplified model for supraspinal facilitation of nociception by RSC-ACC excitatory pathway. The peripheral visual, auditory sensory, and somatosensory inputs (the orange lines) are conveyed to the thalamus. Then, the thalamus relays these sensory inputs to the cerebral cortex, such as the ACC and RSC. The ACC, as a high brain center for pain processing, is innervated by not only the subcortical thalamus but also the supracortical RSC (the red arrow lines) to integrate the nociceptive information. The excitatory RSC-ACC pathway probably involves in the combination of pain processing and memory (such as the pain-related contextual memory) by an engram mechanism in the RSC.
Most studies on #nociceptive pathways focus on links between subcortical regions & #SpinalCord, but what about cortico-cortical circuits? This study reveals a pathway from retrosplenial cortex to anterior cingulate #cortex that modulates #pain perception 🧪 @plosbiology.org plos.io/4hcS2iB
Image of a tree with pink hearts for leaves on a pink background. The text over the image reads: 7,670 DAYS TOGETHER! but who's counting? HAPPY 21ST ANNIVERSARY
So, the text in the image is a misnomer.
Today marks the 21st anniversary of my last pain-free day.
So, that's a 'fun' fact.
I have it all: #Nociceptive, #neuropathic, #nociplastic, acute and chronic.
Feel free to send #spoons or cute animal pics anytime you can :)
Some active tags in the #painscience feed
#painresearch #painneuroscience #painmedicine #painmed #nociception #chronicpain #neuroplasticity #neuropathic #nociplastic #nociceptive #neuropathicpain #nociplasticpain #paineducation #allodynia #centralsensitization #painmodulation #painmodulation #IASP
Welcome to the #painscience feed. There are many hash tag combinations to use so you don’t have to think too much like: #painresearch #chronicpain #painneuroscience #painmedicine #nociception
#painmed
#paineducation #neuropathic #nociplastic #nociceptive #neuroplasticity
