Refining capsaicin-induced pain models: A comprehensive analysis of preclinical practices and their translational potential Pain remains a significant clinical challenge despite advances in mechanistic understanding. Animal models have been instrumental in advancing our und…

Excited to share our #Neuroscience & Biobehavioral Reviews #paper on a common #neuropathic #pain model to understand pain and test treatments. Does it work for both? For women or young people? @profmarkhutchinson.bsky.social @buisman.bsky.social

www.sciencedirect.com/science/arti...

Dear Bsky Friends, #shoulder pain phenotyping: a practical guide for clinicians to determine predominant nociceptive, #neuropathic, or #nociplastic shoulder #pain incl. three case presentations. Open access until Oct 15: authors.elsevier.com/c/1lg2i51N1w...

My journey with #neuropathic #pain has been a rough one.
From #physio to #meds and every intervention in between.
RF ablation, targeted nerve blocks, steroids all failed 😟
Great support from my #GP but pain management in #Ireland is a hard slog
My next step, getting #SpinalStimulator #SCS implant 🤞

Differential Effects of Pregabalin and Morphine on the Sleep-Wake Cycle and Circadian Rhythms in Mice with Neuropathic Pain - PubMed Pregabalin, unlike morphine, restores SNI-disrupted sleep architecture, circadian rhythms, and spinal circadian gene expression.

🎉 Excited to share that our latest research has been accepted for publication in Anesthesiology!

Both #pregabalin and #morphine relieve #pain in mice with #neuropathic pain, but only pregabalin stabilises REM #sleep, sleep #spindles and #circadian #rhythms.

pubmed.ncbi.nlm.nih.gov/40802988/

Hydrate well—dehydration can lift pain & fatigue. Sip often; add electrolytes. bit.ly/Tipsoftheday See your CRPS specialist.

#CRPS #ChronicPain #Pain #Hydrate #H2O #Electrolytes #Fatigue #SelfCare #Spoonie #Flare #Nerves #Mindful #Pacing #PT #OT #Rehab #Sleep #Neuropathic #Carers #Whanau #NZ #ACC

Why Does Pain Feel So Different?
Follow me to learn more about: #ChronicPain #Nociceptive #Neuropathic #Nociplastic #neuroplastic #TMS #PainNeuroscience #PainNeuroscienceEducation #PNE #PRT #Neuroplasticity #PainEducation #PainScience

“New Research Sheds Light on Chronic #Neuropathic Pain, the #Endocannabinoid System and Kennedy Pathways”

“New Research Sheds Light on Chronic #Neuropathic Pain, the #Endocannabinoid System and #KennedyPathways”

#ChronicPain
#Disabled
#hEDS
#HypermobileEhlersDanlos

Link here 👉🏻 curaleafclinic.com/chronic-neur...

High on Health: Exploring the Benefits of Cannabis for Wellness - Cannabis News | NUG Magazine High on Health: Exploring the Benefits of Cannabis for Wellness in the United States In recent years, the United States has witnessed a significant shift in the perception and legalization of cannabis...

"This article delves into the therapeutic advantages of cannabis, examining its role in pain management, mental health, and chronic conditions."
#MedicalMarijuana #MedicalCannabis #Marijuana #Cannabis #Wellness #Health #MentalHealth #Benefits #Neuropathic #Pain #ChronicPain #MS #Cancer

Hear insights from:

🧠Prof Patrice Forget – Lessons from #PANDOS
📊Dalila Veiga – #ChronicPain #classification
📋Prof Andrea Truini – #Neuropathic pain assessment
💊Prof Esther Pogatzki-Zahn – #Opioid stewardship

Let’s shape the future of pain care together! 💬

#ESAIC #PerioperativeMedicine

Study Finds Inhaled Cannabis an Effective Treatment for Neuropathic Pain A recent study has found that inhaled medical cannabis improved scores assessing pain and sleep disturbance in patients with neuropathic pain.

"The inhalation of vaporized herbal cannabis is an effective treatment for neuropathic pain, according to the results of a recently published study by German researchers."
#MedicalMarijuana #MedicalCannabis #Neuropathy #Neuropathic #Pain #Sleep #Study

Howard G. Smith MD, AM on Instagram: "Why Women Experience More Pain Than Men When a woman and a man both sustain injuries to their pain-generating nerves, only the woman produces a unique hormone t... 0 likes, 0 comments - drhowardsmithreports on April 2, 2025: "Why Women Experience More Pain Than Men When a woman and a man both sustain injuries to their pain-generating nerves, only the woman pro...

Why Women Experience More Pain Than Men: When a woman and a man both sustain injuries to their pain-generating nerves, only the woman produces a unique hormone that intensifies that pain. #pain #men #women #neuropathic #pannexin1 #leptin #vegf
www.instagram.com/drhowardsmit...

GPR37L1 identifies spinal cord astrocytes and protects neuropathic pain after nerve injury - PubMed Astrocytes in the spinal cord dorsal horn (SDH) play a pivotal role in synaptic transmission and neuropathic pain. However, the precise classification of SDH astrocytes in health and disease remains…

#GPR37L1, a key regulator of spinal astrocytes and neuropathic pain, reduces pain through glutamate transport enhancement, while its deficiency exacerbates pain and hinders recovery #GPR37L1, #Neuropathic #Pain, #Nerve #Injury

Medical Cannabis vs. Opioids: A Better Alternative? After years prescribing opioids, Dr Alexander Van Heerden, a clinical doctor at Releaf with a background in emergency medicine, believes medical cannabis should be considered a first-line treatment op...

"Research shows that medical cannabis not only relieves pain effectively but also works in a number of types of pain, such as “neuropathic” pain – a pain that is notoriously hard to treat."
#MedicalMarijuana #MedicalCannabis #Opioids #Pain #ChronicPain #Neuropathic #PainRelief

If you never had the chicken pox or the #vaccine for it, I recommend getting it. Adult chicken pox #Shingles #chronic #neuropathic pain is no joke. I had shingles 10years ago and right now the nerve damage in my right shoulder makes me want to rip it off.

Can Cannabis Provide Some Relief From Chronic Pain The Fresh Toast - For those who suffer, it can be life altering in a negative way. But can cannabis provide some relief from chronic pain?

"Research indicates cannabinoids may reduce pain severity by 30–50% compared to placebo, particularly in neuropathic and inflammatory conditions."
#MedicalMarijuana #MedicalCannabis #Marijuana #Cannabis #Pain #ChronicPain #Cannabinoids #PainRelief #Neuropathic #Inflammatory #Endocannabinoids

Divergent sex-specific pannexin-1 mechanisms in microglia and T cells underlie neuropathic pain Panx1 channels mediate sex-specific immune mechanisms in neuropathic pain: leptin from CD8+ T cells drives pain in females, while VEGF from microglia mediates pain in males. Panx1-targeted therapies o...

PAIN RELIEF

Divergent #sex-specific pannexin-1 mechanisms in #microglia and #Tcells underlie #neuropathic #pain |

"Chanelling" Novel #Analgesics for Women and Men at #Neuron @cellpress.bsky.social |

Image of a tree with pink hearts for leaves on a pink background. The text over the image reads: 7,670 DAYS TOGETHER! but who's counting? HAPPY 21ST ANNIVERSARY

So, the text in the image is a misnomer.

Today marks the 21st anniversary of my last pain-free day.

So, that's a 'fun' fact.

I have it all: #Nociceptive, #neuropathic, #nociplastic, acute and chronic.

Feel free to send #spoons or cute animal pics anytime you can :)

Some active tags in the #painscience feed
#painresearch #painneuroscience #painmedicine #painmed #nociception #chronicpain #neuroplasticity #neuropathic #nociplastic #nociceptive #neuropathicpain #nociplasticpain #paineducation #allodynia #centralsensitization #painmodulation #painmodulation #IASP

Welcome to the #painscience feed. There are many hash tag combinations to use so you don’t have to think too much like: #painresearch #chronicpain #painneuroscience #painmedicine #nociception
#painmed
#paineducation #neuropathic #nociplastic #nociceptive #neuroplasticity

Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action - Bioelectronic Medicine Well-established in the field of bioelectronic medicine, Spinal Cord Stimulation (SCS) offers an implantable, non-pharmacologic treatment for patients with intractable chronic pain conditions. Chronic...

Hello👋🏻 Anyone any experience with #SCS for Pts with chronic #neuropathic #SCI pain.? Seems to be a personal last gasp solution as all the #opiods & #ketamininfusions got me nowhere! 😕

#spinalcordinjury #neurosugery #neurology #chronicpain 🩻

bioelecmed.biomedcentral.com/articles/10....

Review of Studies on Cannabis for Neuropathic Pain Researchers analyzed studies from the past two decades on the impact of cannabinoids on neuropathic pain and potential benefits.

Review of #Studies on #Cannabis for #Neuropathic #Pain

www.cannabissciencetech.com/view/review-... #MMJ #weed

"@CochranePaPaS: No good quality evidence in topical lidocaine for #neuropathic pain http://ow.ly/zEIZj" Hope ongoing RCTs are helpful..