08 BONE DEVELOPMENT AND GROWTH, OSSIFICATION PROCESS EXPLAINED #50LAM_ANATOMY_ENG
youtube.com/shorts/MJLVK...
#Anatomy #BoneDevelopment #Ossification #BoneGrowth #SkeletalSystem #EpiphysealPlate #Osteoblasts #Osteoclasts #BoneHealth #Physiology

07 BONE STRUCTURE AND COMPOSITION, FUNCTIONS AND CELL TYPES #50LAM_ANATOMY_ENG
youtube.com/shorts/VoEFP...

#Anatomy #BoneStructure #SkeletalSystem #Physiology #BoneCells #CompactBone #SpongyBone #Osteoblasts #Osteoclasts #BoneHealth

Dr. Jewett's study reveals osteoclasts activate NK, CD3+ T & γδ T cells, with highest IFN-γ secretion when cells interact with zoledronate-treated osteoclasts, offering BRONJ insights.

Free until March 15: dl.begellhouse.com/journals/2ff...

#BRONJ #Osteoclasts

NKD2 directs #MesenchymalStemCell fate toward #osteoblasts, inhibits #osteoclasts via Wnt/β‑catenin and mTORC1, and reduces #boneloss in vivo, highlighting NKD2 as a therapeutic target for #osteoporosis.

#OpenAccess: doi.org/10.1016/j.ge...

Naked cuticle homolog 2 (NKD2) regulates osteoblast and osteoclast differentiation and improves bone loss in ovariectomized mice.
#NKD2 #Osteoblasts #Osteoclasts #BoneLoss #BoneMetabolism #OsteoporosisModel
doi.org/10.1016/j.ge...

It’s really wild to feel your bone spicules and tooth shards working their way out of your gums on the whole top row at once. It generally doesn’t even hurt!

Like what can’t a body do!?!?

Thanks for keeping it real, #Osteoblasts and #Osteoclasts 🫶🏻 🦷

Cathepsin K inhibitors promote osteoclast-osteoblast communication and engagement of osteogenesis Abstract. Cathepsin K inhibitors are well known for their inhibitory activity against bone resorption but were also reported to preserve bone formation in

New paper out in JBMRPlus !
Using a time-lapse co-culture approach with #osteoclasts and reversal cells, we show that reversal cells prefer pits over trenches, but that intermediate #CatK inhibition boosts their attraction and maturation into #osteoblasts.
track.smtpsendmail.com/9032119/c?p=...