I’m a geologist and I have no idea what any of this means, but my husband wrote this paper and he named it Theropod because he’s a vertebrate paleontologist who does #proteomics and #paleoproteomics

I am pleased to share that on December 18, I received the Award for the Best Researcher of the Year at Vilnius University in the Open Science category. This recognition was granted for my work on untargeted #paleoproteomics for the biological sex identification of archaeological remains

BJU International Paleo proteomic study of blood residues shows that Voltaire (1778) died of perforated bladder squamous cell cancer with peritoneal extension Read More

Analysis of biological samples from Voltaire’s preserved heart suggests he died from advanced bladder cancer, resolving a centuries-old medical question through modern paleoproteomic techniques.

Read now! https://ow.ly/Wc0A50XLrmR
#MedicalHistory #Paleoproteomics #Urology #ScienceMeetsHistory

MALDI Deamidation Score (MDS): A fast and flexible method for assessing deamidation in ZooMS data and its application to the Denisova Cave bone assemblage Estimating deamidation from ZooMS spectra has frequently been achieved using the q2e method due to its high-throughput capacity and ease of use. Despi…

🧬 MALDI Deamidation Score (MDS) — a fast, scalable method for estimating collagen deamidation directly from ZooMS data. Peptide- and sample-level deamidation from team from @cam-archaeology.bsky.social and @unituebingen.bsky.social

#ZooMS #Paleoproteomics #DenisovaCave

New clues from 2 million-year-old tooth enamel tell us more about an ancient relative of humans Researchers have extracted 2-million-year-old protein remains from Paranthropus robustus teeth to reveal biological sex and genetic variability.

New clues from 2 million-year-old tooth enamel [via The Conversation] 🧪🥼💀🦷

"first documented time we can show #heterozygosity (a state of having two different versions of a #gene) in #proteins that are 2 million years old."

theconversation.com/new-clues-fr...

#Paleoproteomics #ancient #humans

💡 How to ID archaeological bones in resin?A team of researchers, including ICArEHB members Paul Goldberg, Shannon McPherron, William Chase Murphree, and Vera Aldeias explore new paleoproteomics methods.
🔗 doi.org/10.1093/pnas...
#Archaeology #Paleoproteomics #ICArEHB

New methods on the block: Taxonomic identification of archaeological bones in resin-embedded sediments through paleoproteomics Abstract. The integration of biomolecular studies of past organisms with geoarchaeological studies can significantly improve our understanding of the relat

New paper is out!

We and welkergroup.bsky.social show that proteins from resin-impregnated sediment blocks can reveal faunal diversity at the microscale.
We thank and congratulate all coauthors!
#paleoproteomics #geoarchaeology
erc.europa.eu
icarehb.bsky.social
academic.oup.com/pnasnexus/ar...

Would you do tissue proteomics with an old sample fixed in formalin, not embedded in paraffin, and stored for quite a while immersed in formalin?? Can the proteins be extracted after subjecting to decrosslinking?? Are there any insights to share from the #paleoproteomics practitioners?? Thanks..

New methods on the block: Taxonomic identification of archaeological bones in resin-embedded sediments through paleoproteomics Abstract. The integration of biomolecular studies of past organisms with geoarchaeological studies can significantly improve our understanding of the relat

📄 New paper 📣 of @matrixerc.bsky.social & @welkergroup.bsky.social! We show that microstratigraphic-scale #paleoproteomics works in intact sediments - opening new ways to explore ancient ecosystems & hominin behaviour 🌍🦴
@erc.europa.eu @icarehb.bsky.social 🔗 academic.oup.com/pnasnexus/ar...

Protein and chitin preservation in polymeric sheets in Miocene <em>Ecphora gardnerae</em> shells from Maryland, USA - Acta Palaeontologica Polonica

New #paleoproteomics paper by @paleoproteomicist.bsky.social and colleagues. This time on Miocene gastropods from Maryland!

www.app.pan.pl/article/item...

Pr. Jaroslav Brůžek was a notable biological anthropologist based in France and the Czech Republic. He has contributed significantly to the understanding and development of new methods and tools for the sex identification of human remains, including #paleoproteomics

New Breakthrough in Paleoproteomics: Visualizing Ancient Proteins in Fossils A joint research from Okayama University and others has developed a technique to visualize ancient proteins in fossils, potentially aiding in dinosaur studies.

New Breakthrough in Paleoproteomics: Visualizing Ancient Proteins in Fossils #Japan #Okayama #Okayama_University #Paleoproteomics #Fossil_Research

#paleoproteomics #Africa

Another #paleoproteomics paper also dropped today. This is ancient enamel from the Arctic

Eighteen million years of diverse enamel proteomes from the East African Rift - Nature The isolation of dental proteins from fossils deposited 1.5 million to 18 million years ago in the Turkana Basin in Kenya, a tropical region, demonstrate the promise of dental enamel for palaeoproteom...

It’s finally out! 18 million year old enamel proteins from the Turkana Basin, Kenya @paleoproteomicist.bsky.social #paleoproteomics #proteomics 🧪 ⚒️

www.nature.com/articles/s41...

We’ve had a Denisovan skull since the 1930s—only nobody knew https://arstechni.ca #skeletonsandskeletonaccessories #paleoanthropology #ancientproteins #paleoproteomics #anthropology #Neanderthals #Archaeology #ancientDNA #Denisovans #proteomics #hominins #Science #science #skulls

How Ancient Brains Are Giving Up Their Secrets A new Oxford-led method is unlocking thousands of ancient proteins from soft tissues like brains—reshaping how we understand disease, memory, and human history.

Researchers just decoded 1,200 proteins from 200-year-old human brains—offering unprecedented insights into ancient health and disease. #Paleoproteomics #AncientBrains #OxfordResearch

Dinosaur Fossils May Help Unlock the Future of Cancer Research Scientists find red blood cell-like structures in a dinosaur bone — opening new possibilities for studying cancer through ancient molecular preservation.

Red blood cell-like structures in a dinosaur fossil hint at ancient disease mechanisms — and may inspire new cancer breakthroughs. #paleoproteomics #dinosaurfossils #cancerresearch

Teeth, Proteins, and Paranthropus: Cracking Open an Ancient Mystery How 2-Million-Year-Old Tooth Enamel Is Rewriting the Story of a Hominin Enigma

Ancient tooth proteins show Paranthropus robustus wasn't just dimorphic—its variation went deeper. Male tooth, small size. DNA gone, but enamel remembers. #Paleoproteomics #Paranthropus #HumanEvolution #AncientProteins #FossilScience @science.org

Enamel proteins reveal biological sex and genetic variability in southern African Paranthropus Paranthropus robustus is a morphologically well-documented Early Pleistocene hominin species from southern Africa with no genetic evidence reported so far. In this work, we describe the mass spectrome...

🚩 #newpublication ! 🦷💀😱
A groundbreaking study published in #Science on #Paranthropus robustus sex diagnosis via #paleoproteomics, co-authored by our SAP member @clement-zanolli.bsky.social from @pacea.bsky.social! #palaeoanthropology #biologicalanthropology www.science.org/doi/10.1126/...

How Preserved Human Brains Are Rewriting Paleoproteomics Decoding the Deep Past through Ancient Proteins

Victorian-era brains excavated in Bristol yield 1,200+ ancient proteins—reshaping how we study disease, memory & soft tissues in the past. A new frontier in bioarchaeology. #paleoproteomics #archaeology #ancientDNA #humanhistory

Penghu 1 mandible in hand

#Paleoproteomics played a key role here. By thoroughly testing extraction strategies using Penghu faunal bones, we obtained a high-quality ancient proteome from Penghu 1 with minimal destruction. We detected multiple Denisovan-related variants and identified a male-specific isoform.

Thread 5/5: 🧬 Amber's preservation capabilities for proteins remain debated.

While promising, paleoproteomics requires exceptional methodology to distinguish genuine ancient proteins from contamination. Let's wait for peer review and independent verification. #paleoproteomics #scienceskepticism 🙂

Arthropod Parasitiformes amber inclusions. (A) Holothyrida, Neothyridae. A scavenger mite found together with insect inclusions in the amber from which it was separated for analysis. The figures provide details of the general look of the piece, measurements, and critical details for identification. Insect inclusions and amber without inclusions derived from this amber piece were processed as controls. (B) Cornupalpatum tick species for which stereomicroscope and Scan Ct images show the damage of the body preventing an accurate determination to the species level.

Neothyridae gen. sp. Elongation factor 1-alpha (A0A2H4RIF7). Sequence and phylogenetic analysis of the protein identified with highest coverage (244/342 amino acids, 71.3%). Neothyridae form a separate clade within Holothyrida mites.

Thread 1/5: PREPRINT: A major milestone on #Paleoproteomics?

Sciex 6600 TripleTOF analyses 99-million-year-old arthropods 🕷️ in amber.

Study identifies proteins from #Cretaceous #Holothyrida mites & #Cornupalpatum ticks!

de la Fuente et al. (2025) www.researchsquare.com/article/rs-6...

At Teotihuacan, a major Mesoamerican city, we’ll be using our new database of avian proteins (doi.org/10.21203/rs....) to identify fragmented bones and eggshells and reconstruct the role of wild and domesticated birds in the subsistence strategies of the city’s residents. #paleoproteomics #MSCA

Ancient Proteins Unlock the Identity of a 3.5-Million-Year-Old Hominin A New Tool for Studying Early Human Relatives

Scientists used ancient proteins to determine the sex of a 3.5-million-year-old Australopithecus africanus—a first in human evolution research. #HumanOrigins #Fossils #Paleoproteomics #HumanEvolution #Paleoanthropology #Australopithecus

Our new paper will be of interest for #archaeology #zooarchaeology and anyone interested in the application of #paleoproteomics: "Improving Identification of Caprine Mandibles: Integrating Morphological and ZooMS Analyses" authors.elsevier.com/c/1kXSl,rVDB... now in JAS Reports.

The XI National Conference of Archaeozoology (AIAZ) starts today. BonesLab will be present with several works.

www.muse.it/eventi/xi-co...

#archaeozoology #paleoproteomics #ZooMS #BonesLab #Muse #Paleolithic #Italy

Paleoproteomics sheds light on million-year-old fossils - Nature Reviews Molecular Cell Biology Ancient proteins can provide phylogenetic information at a timescale that supersedes ancient DNA. Paleoproteomics could thus provide invaluable evolutionary insights, including into human evolution.

NatureRevMCB by Ryan Paterson, Palesa Madupe & Enrico Cappellini

3.8M year old horse 🐎 tooth 🦷 yielded 60+ proteins covering ~10k amino acids.

Single-molecule sequencing tech a game-changer?

💀 Decolonization & democratization of human evolution studies
🦕 ?
#paleoproteomics #evolution