girl remember my #parenchyma

These #Tregs appear to restrain #IFN gamma production & #inflammation (by regulating #IL-2 levels), inhibit immunocyte infiltration into the #parenchyma, restrain #glial cells in #hippocampus, regulate #hippocampal #neurogenesis, & promote short-term #memory!

The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis Meningeal regulatory T cells restrain local interferon-γ–producing lymphocytes, thereby safeguarding parenchymal brain homeostasis.

A #Science #Immunology Instant Release:
@mmr2.bsky.social, Diane Mathis, & colleagues at @harvard.edu & @institutocajal.bsky.social describe specialized meningeal #Treg subsets that promote #homeostasis of the mouse #brain #meninges & #parenchyma!