#Pericrine #Glioblastoma #Chemoresistance
Pericyte CCL5▶️Tumor cell CCR5▶️ ⏫#DNADamageRepair
Pericyte ablation or Maraviroc (CCR5i) sensitize Glioblastoma xenograft to Temozolomide
Apoptotic tumor cell⏫with distance to pericyte in recurrent glioblastoma
#CellRes 2021
www.nature.com/articles/s41...
Review article by Alexander M. Jordan et al., #Angiocrine and #pericrine signaling: how endothelial cells and pericytes drive cancer progression and therapy resistance
➡️ https://ow.ly/t2kR50X8pG3
#TherapyResistance #EndothelialCellsandPericytes
#Angiocrine & #Pericrine signaling: how #EndothelialCells & #Pericytes drive cancer progression and therapy resistance
Hodivala-Dilke lab #PhysiolRev 2025
journals.physiology.org/doi/abs/10.1...
Anyone can share a reading link?🙏
Behind the paywall💰😩
Lung #Pericyte #Fibrosis
Tuj1/βIIITub+ Pericyte expands in #Bleomyin-induced mouse #PulmonaryFibrosis
A potential anti-fibrotic #Pericrine CXCL10
Not Collagen-depositing
Tubb3 KO🐭➡️exacerbated fibrosis
#SciArt
Yoh-suke Mukouyama lab bioRxiv 2025
www.biorxiv.org/content/10.1...
#Pericrine #Angiogenesis
#Pericyte-derived TIMP3
⏫ #EndothelialCell tubulogenesis (⏬EC cord diameter ⏫length branching basement membrane) in a 3D collagen EC-pericyte co-culture model
#FrontCellDevBio 2024
@ondinecleaver.bsky.social
www.frontiersin.org/journals/cel...
#COVID19
Liver-Lung Crosstalk
#Pericrine
#Pericyte-derived #TissueFactor likely a major contributor to #PortalVein Sclerosis & Microthrombi, + minimal inflammation
Portal venopathy corr. intrapulmonary vascular dilation in fatal #COVID19😲
#JHepatology 2024
www.sciencedirect.com/science/arti...
#Pericyte-derived PDGFRβ+ #Microvesicle after👤#Stroke 0~144 h
⏫plasma concentration
Constitute <0.0001% of total plasma #ExtracellularVesicle
#ProximityExtensionAssay->microvesicle protein content-> Angiogenic, inflammatory & HedgeHog #Pericrine
#Stroke 2024
www.ahajournals.org/doi/abs/10.1...
2/3
Diabetes⏬pericytic LBH & mutes #Pericyte crosstalk with #EndothelialCell subclusters in cavernous tissue
How viral LBH delivery⏫cavernous #Angiogenesis #Neurogenesis?
LBH binds to Vimentin & αB-crystallin in pericyte🧐
Impacts on #Pericrine?
Non-pericytic effects?
