In this discovery approach, we characterize the protein interactive network of the #kinase #SRPK1 and the #phosphatase #PPP1CC, revealing proteins involved in key processes for #sperm development and expanding their roles in maintaining proper testicular activity.

The protein phosphatase OsPP1a dephosphorylates and stabilizes CatC to scavenge excess H2O2 and enhance salt tolerance in rice One-sentence summary: OsPP1a dephosphorylates CatC to promote its stability and activity by inhibiting its ubiquitination and degradation, thereby scavenging excess H2O2 and enhance salt tolerance sal...

The protein #phosphatase OsPP1a dephosphorylates & stabilizes CatC to #scavenge excess #H2O2 and enhance #salt tolerance in #rice

www.cell.com/plant-commun...

#PlantScience #StressBiology #AbioticStress @mplantpcom.bsky.social @plantredox.bsky.social @plecevo.bsky.social @plantprotein.bsky.social

Differences in root phosphatase activity (RPA) between growth forms (a), N-fixing ability (b), and mycorrhizal types (c).

Linking root #phosphatase activity to root chemical and morphological traits across species: a global analysis

Gukailin Ao, et al.

nph.onlinelibrary.wiley.com/share/ZTVBGH...

#PlantScience

The tyrosine #phosphatase PTPN22 functions as a scaffold protein to maintain mTORC2 complex integrity and function, independent of its phosphatase activity.
#cellsignaling

-> www.embopress.org/doi/full/10....

Phosphatases: from basic research to translation Phosphatases have been considered undruggable for decades. However, recent breakthroughs with the first small molecule phosphatase inhibitors for cancer immunotherapy now in clinical trials have resu…

Join scientists, biotech start-ups and pharmaceutical companies to discuss #phosphatase research at the EMBO Workshop "Phosphatases: From basic research to translation" in Würzburg, Germany, 27–31 July

Deadline: 15 May 2025

meetings.embo.org/event/25-pho...
#EMBOphosphatases #EMBOevents 🧪

Microbial dilution: revealing the functional value of microbial #diversity by experimental approaches. Phosphatase activity in P-rich #soils decreases more by microbial dilution than in P-poor ones --> higher #phosphatase diversity in #recycling #ecosystem tinyurl.com/32ezdjmt by @dfg.de #SPP1685

Phosphatases: from basic research to translation Phosphatases have been considered undruggable for decades. However, recent breakthroughs with the first small molecule phosphatase inhibitors for cancer immunotherapy now in clinical trials have resu…

Join scientists, biotech start-ups and pharmaceutical companies to discuss #phosphatase research at the EMBO Workshop "Phosphatases: From basic research to translation" in Würzburg, Germany, 27–31 July

Deadline: 11 April

meetings.embo.org/event/25-pho...
#EMBOphosphatases #EMBOevents 🧪

Oh boy, #PP2A again contaminating #phosphatase research. First it was physiological PP2A binding that explained the S/T PPase activity of Eye, now it is a real contamination of PHLPP1/2 protein preps. Important work that forces to entirely rethink the past literature on PHLPPs.

@westermarcklab.bsky.social proudly presents: The lab logo. Only took 23 years to have it done, but here it is. Big credits to Henok Karvonen at @turkubioscience.bsky.social for beautiful design. Embedded cancer cell #signaling by #phosphorylation and #dephosphorylation #phosphatase

A mechanism for hypoxia-induced inflammatory cell death in cancer - Nature We find that PTP1B and ABL1/2 reciprocally control RNF213 tyrosine phosphorylation and its oligomerization and RZ domain activation, and identify a unique PTP1B–RNF213–CYLD–SPATA2 pathway critical for...

this week #JournalClub @labsoap.bsky.social #CYLD #SPATA2 #ubiquitination #dUB #Phosphatase #hypoxia @nature.com www.nature.com/articles/s41...

Phosphatases: from basic research to translation Phosphatases have been considered undruggable for decades. However, recent breakthroughs with the first small molecule phosphatase inhibitors for cancer immunotherapy now in clinical trials have resu…

If you’re thinking of what meeting to go to this year then check out the #phosphatase meeting in Würzburg. Lots of great speaking slots and events for junior researchers. It’s always a fun meeting meetings.embo.org/event/25-pho...

Hello BlueSky! I’m a cell signaling biologist + Kinase enthusiasts. Looking forward to connecting with groups and labs working in the realm of post translational modifications! #kinase #phosphatase #cellsignaling #phosphorylation