#immunity #Tcells #mRNA #HuR #smFISH #RNAbiology

Super-resolution microscopy of mitochondrial mRNAs - Nature Communications Stoldt, Maass, and colleagues present a study where smFISH is combined with STED and MINFLUX microscopy to map mitochondrial mRNA at nanometre resolution, enabling the exploration of the structural fo...

#Mitochondria researchers listen up:
Stoldt et al. established protocols for #superresolution microscopy of mitochondria, combining #smFISH with #STED and #MINFLUX. They investigate spatial relationships between specific mRNAs and proteins and distinct mRNA shapes.
www.nature.com/articles/s41...

🔬 Our latest #Microscopy #AppNote details a method using #smFISH to report the delivery efficiency and knockdown efficacy of an siRNA therapeutic using our Ti2-E inverted microscope and NIS-Elements software with General Analysis 3 (GA3) module.

🔗 Click to check it out: bit.ly/46tlEpc

#Microscope

🧬 Understanding how drugs work at the molecular level is important for #DrugDevelopment. #smFISH is used to quantify how drugs impact mRNA expression.

🔗 Our #NikonBioImagingLabUSA team has extensive smFISH experience and are ready to assist you: bit.ly/45VeIAX

#CRO #ContractResearch #Microscopy

#Baysor

#CellSegmentation for 2D 3D image-based #SpatialTranscriptomics

Based on Transcript composition #MarkovRandomField
-/+Stain image #PriorSegmentationConfidence

Work with #MERFISH #smFISH #STARmap
⏫Detection of vascular cells

#NatureBiotech 2022
www.nature.com/articles/s41...