Memory CD8+ T cell diversity and B cell responses correlate with protection against SARS-CoV-2 following mRNA vaccination - Nature Immunology Pace and colleagues assessed the antibody titers, B cell and T cell memory response against SARS-COV-2 in mRNA-vaccinated individuals to show that reduced antibody titers combined with a distinctive memory T cell profile in low vaccine responders correlated with breakthrough infection.

New @NatImmunol #publication, led by twitterless Luigia Pace @IIGM_genomics. #wemakeproteins #collaborations #immunology @DBB_UniPV @unipv https://www.nature.com/articles/s41590-022-01313-z

#wemakeproteins and sometimes we also deliver them! #research #collaboration #luigiapace #immunology @ArmeniseHarvard @IIGM_genomics @DBB_UniPV @unipv

Frontiers | Epidemic Preparedness—Leishmania tarentolae as an Easy-to-Handle Tool to Produce Antigens for Viral Diagnosis: Application to COVID-19 To detect and prevent emerging epidemics, discovery platforms are urgently needed, for the rapid development of diagnostic assays. Molecular diagnostic tests...

New #publication! Nice collaboration with @gab_paolo
@epis_sara @Irene68212358 @LaStatale describing usage of LLeishmania tarentolae to produce #SARSCov2 #RBD for #sierological assays #wemakeproteins @DBB_UniPV @unipv

https://t.co/7A8SIkyd5C

A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis - Nature Communications UNC5B is a Netrin-1 receptor expressed in endothelial cells that in the absence of ligand induces apoptosis. Here the authors identify an UNC5B splicing isoform that is insensitive to the pro-survival ligand Netrin-1 and is required for apoptosis-dependent blood vessel development.

New #publication! Again excellent collaboration with twitterless Claudia Ghigna, presenting a novel ligand-insensitive UNC5B #splicing isoform regulating #angiogenesis and #apoptosis. Out today in @NatureComms #wemakeproteins @DBB_UniPV
@unipv
@CNRsocial_ https://doi.org/10.1038/s41467-021-24998-6

Using SEC-MALS, we compared recombinant #SARSCov2 #RBD using our HEK293 cells and Leishmania tarentolae #wemakeproteins #biophysics @gab_paolo @unipv @LaStatale @DBB_UniPV https://x.com/epis_sara/status/1413074743176179713

New #publication! Interested in how #wemakeproteins ? Check our @bioprotocolbyte #methods paper! https://bio-protocol.org/e3998 @DBB_UniPV @unipv @ArmeniseHarvard @AIRC_it @FondCariplo @MSCActions

Frontiers | IgG Antibody Responses to the Aedes albopictus 34k2 Salivary Protein as Novel Candidate Marker of Human Exposure to the Tiger Mosquito Mosquitoes of the Aedes genus transmit arboviruses of great importance to human health as dengue, chikungunya, Zika and yellow fever. The tiger mosquito Aede...

New #publication! Excellent collaboration with @gab_paolo @LaStatale and the Arcà Group @SapienzaRoma #wemakeproteins @unipv @dbb_unipv https://doi.org/10.3389/fcimb.2020.00377 https://x.com/gab_paolo/status/1288478368250372098

Our #COVID19 activity ended up in the national news today @Tg1Raiofficial. #wemakeproteins for #serological #tests with @IEOufficiale @DBB_UniPV @unipv

#wemakeproteins #somanyaliquots #covid19proteins #iceicebaby @DBB_UniPV @unipv

#wemakeproteins #shakeitshakeit #HEK293 #COVID19proteins @DBB_UniPV @unipv

Un passo avanti per mappare i contagi. Ecco il test da 2 cent a paziente Prodotto dall'Istituto europeo di Oncologia in collaborazione con il Mount Sinai Hospital di New York, è in grado di rilevare gli anticorpi per il Covid. Sensibile e specifico, è riproducibile da qualsiasi laboratorio con competenza accademica

#wemakeproteins and together with our friends in @IEOufficiale @spasqualato are developing a cheap and reliable #serologicaltest for #COVID__19 https://t.co/tyoVw8PToL @unipv @DBB_UniPV

Our lab has joined #IEO_Milano for the development of a sierological test to detect #coronavirus #antibodies. Today we are in the news @RaiTre #wemakeproteins @unipv @DBB_UniPV