By attenuating #ERstress and chondrocyte #Apoptosis, melatonin mitigates Slc26a2-associated #Chondrodysplasias, promoting #Chondrocyte survival, partially alleviating growth retardation, and improving trabecular #BoneFormation. #medsky
#OpenAccess: doi.org/10.1016/j.ge...
An overview of the regulatory role of #m6Amodification in #BoneFormation & #StemCell directional differentiation, its pathological role & underlying mechanisms in #BoneDiseases, and m6A targeting therapeutic strategies.
#OpenAccess: doi.org/10.1016/j.ge...
Insights into how adhesion G protein-coupled receptor 133 contributes to #BoneFormation through local cell-cell interactions between osteoblasts and osteoclasts, making it a promising candidate for treating osteopenic conditions.
#STTT #OpenAccess: doi.org/10.1038/s413...
The #mechanosensitive channel #Piezo1 in #BMMSCs suppresses #BoneMarrow #adipogenesis and promotes #BoneFormation by blocking the Ccl2–Lcn2 inflammatory loop, linking #mechanotransduction to #inflammation control and bone strength.
#OpenAccess in #STTT: doi.org/10.1038/s413...
MSDC-0602K, a next-generation #TZD, rewires metabolism in bone marrow stem cells - promoting #BoneFormation while reducing #BMAT accumulation. This tissue-specific approach opens new doors for safer #Diabetes treatments! The paper is archived at bma-society.org/paper-of-the...
Latest Advances in Structural Insights and Quantification Techniques for Type I Collagen Biomarkers: A path toward standardization?
@journals.sagepub.com @biomarkerinsights.bsky.social
journals.sagepub.com/doi/10.1177/...
#bonemarker #boneturnover #boneformation #medicine #medsky #openaccess
