Sergiu A. Lucaciu of westernu.bsky.social et al. observed that skin disease-associated GJB4 variants differentially influence #connexin stability, cell viability and channel function ⚙️ 🔍
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🤩Excited for #AAIC2025.
🤝Join us
@alzassociation.bsky.social
conference in Toronto, 🇨🇦 👐learn how we are closing gaps in #dementia 🧠 #imaging in #Africa
👉Discover our #CONNExIN & #SWiM imaging training programs-starting soon event.fourwaves.com/connexin and event.fourwaves.com/swim/pages
In @jgp.org, Gong, Abrams et al. present two novel, disease-causing genetic variants of #connexin 47. In vitro assays and MD simulations reveal unique mechanisms that relate connexin 47 mutations to severities of Pelizaeus–Merzbacher-like disease 1. rupress.org/jgp/article/...
Gong, @jennoligomyelin.bsky.social, Abrams et al. present two novel, disease-causing genetic variants of #connexin 47. In vitro assays and MD simulations reveal unique mechanisms that relate connexin 47 mutations to severities of Pelizaeus–Merzbacher-like disease 1. rupress.org/jgp/article/...
Last Friday Iwent to the first reunion of MANGO (Mid-Atlantic Nexin Group Organization) in Charlottesville, Virginia, and it was awesome! Thanks Lillo lab for the support!
And thanks my husband Camilo, who joined me to explore more the city and find good pizza 🙂
#connexin #womeninstem #postdoclife
Mind the Gap? This study re-examines #gapjunctions in the Zona #glomerulosa of mouse #adrenal #cortex, reporting RNA and protein expression of #connexin 43 and 37. However, in adrenal slice cultures, only limited evidence for GJ function was obtained.
https://buff.ly/40FEt3V
#CellCommunication
Tonabersat suppresses priming/activation of the NOD-like receptor protein-3 (#NLRP3) inflammasome and decreases renal tubular epithelial-to-macrophage crosstalk in a model of diabetic kidney disease biosignaling.biomedcentral.com/articles/10....
👇👇👇 #hemichannels #connexin #inflammation #NephSky
