Epigenetic Signatures in Monozygotic and Dizygotic Twins Discordant for Orofacial Clefts Introduction: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital malformation with complex etiology involving both genetic and environmental factors. Epigenetic mechan...

🧬 New preprint alert! Excited to share our twin study on the epigenetics of orofacial clefting — available on #medRxiv. 🔬 🧪
www.medrxiv.org/content/10.6...
#cleftlipandpalate #twinstudies #uiowadentistry #womeninscience #uiowaresearch #nidcr #epigenetics #dnamethylation #EWAS

Wrapping up a wonderful week at #IADR2026. Had a great time meeting colleagues and friends, making new connections and above all, watching these girls shine at their poster sessions - #proudmentor 😍 🦷 🧬 🧪 🔬 💪🏻
#uiowadentistry #cleftlipandpalate #epigenetics #uicod #womeninscience #AADOCR #IADR2026

A heartfelt thank you to an incredible team that traveled to Guatemala to provide 5 cleft lip and palate surgeries. Grateful for their humanitarian commitment to giving children the opportunity to thrive.

#HeartsInMotion #CleftLip #OralSurgery #MedicalMission #CleftLipAndPalate #OralSurgeryMission

So proud of these amazing young scientists and all their hard work! Congratulations, ladies, thank you for being part of this group and for representing our lab🧬 🔬 🧫. #uiowadentistry #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience
#proudmentor

Ready for the 73rd Iowa Section of the AADOCR. Come see our work on Genomics and Epigenomics of Orofacial Clefts and Van der Woude Syndrome. #uiowadentistry #uiowaresearch #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience

CRISP grant supports study of genetic variation in Van der Woude syndrome Aline Petrin, assistant professor of orthodontics, received a CRISP grant to complete genetic screening of patients with Van der Woude syndrome. Her study will help clarify how genetic mutations influ...

Grateful for the continued support to our research program! 🙏 🧬 🔬 #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod
#womeninscience #vanderwoude
University of Iowa College of Dentistry and Dental Clinics

dentistry.uiowa.edu/news/2025/09...

Kicking off two days of learning and scientific networking at the University of Minnesota. Come see poster 31 to learn more about our work on Methylation Quantitative Traits and Orofacial Clefts #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #scgdb2025

I thoroughly enjoyed being able to write this comprehensive piece highlighting the team behind Shriners Children's Boston Cleft and Craniofacial Center.

Read more about the staff: www.shrinerschildrens.org/en/news-and-...

#ShrinersChildrens #CleftLipAndPalate #CraniofacialCare #MedSky #BlueSky

Another Hatton Award for Iowa! Congratulations, Saba Manafi for winning 2nd place Junior Category! It is so rewarding to see your hard work recognized. #proudmentor 🎉 ❤️ #IADR2025 #uiowadentistry #uiowaresearch #cleftlipandpalate #womeninscience #oavs #PetrinLab

Register your interest here:
www.bristol.ac.uk/dental/resea...

#cleft #cleftresearch #cleftcare #cleftlipandpalate #cleftstrong #cleftcommunity #cleftproud #cleftlip #cleftpalate #bornwithcleft #bornwithcleftlipandpalate

Cleft@18-23 is a research programme investigating outcomes at the end of routine care for young adults born with a cleft.

Sign up today by clicking the link in bio!
#cleft #cleftresearch #cleftcare #cleftlipandpalate #cleftstrong #cleftcommunity #cleftproud #cleftlip #cleftpalate #bornwithcleft

Cleft@18-23 study is now recruiting participants across the UK! @cleft1823study.bsky.social

#cleft #cleft18-23 #cleftresearch #cleftlipandpalate

Wrapping the #AADOCR2025 meeting in NYC. What an amazing week of learning, networking and reconnecting with friends! #uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #craniofacial #twinstudies #oavs #aadocr2025 🧬 🦷 🔬 🗽

Another successful day for the Petrin Lab at #AADOCR2025. Great presentations by these bright young scientists. Thank you for your dedication representing our work!
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #twinstudies #aadocr2025 🧬 🦷 🔬

#Proudmentor moment! Super congratulations to this amazing young scientist for all her hard work on this project and for winning second place in the #AADOCR2025 Hatton Competition! Next stop - Barcelona 🇪🇸 #IADR2025
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #womeninscience #oavs

10 days until the #AADOCR2025 in New York City. Come visit our posters and hear from these amazing students about their work on genetic and epigenetics of orofacial clefts. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #genetics #twinstudies #nidcr #aadocr2025

Methylation quantitative loci analysis in nonsyndromic orofacial clefts Objectives: Nonsyndromic orofacial clefts (OFCs) etiology involves multiple genetic and environmental factors with over 60 identified risk loci; however, they account for a minority of the estimated r...

New preprint from the Petrin Lab: doi.org/10.1101/2025...
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl

Because #ArtFight takes place in July, which is also #CleftAwarenessMonth, I drew this mass attack for #ArtFight2024 specifically choosing various artists' characters which have a #cleftlip

#digitalart #teamstardust #cleftpalate #cleft #cleftlipandpalate

#CleftLipAndPalate

DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability - Amanda Seaberg, Waheed Awotoye, Fang Qian, Ligiane A. Machado-Paula, Lindsey Dunlay, Azeez Butali, Jeff Murray, Lina Moreno-... Objective Van der Woude Syndrome (VWS) presents with combinations of lip pits (LP) and cleft lip and/or cleft palate (CL/P, CPO). VWS phenotypic heterogeneity e...

Check out our new paper on DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #vanderwoudesyndrome #lipits #uicod #womeninscience #proudmentor #nidcr #PetrinLab
doi.org/10.1177/1055...

Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57 Background Disturbances in the intricate processes that control craniofacial morphogenesis can result in birth defects, most common of which are orofacial clefts (OFCs). Nonsyndromic cleft lip (nsCL),...

New preprint: Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57. #uiowadentistry #twinstudies #uicod #cleftlipandpalate #nidcr #Epigenetics
www.medrxiv.org/content/10.1...

🙏For a 📙, I seek a clear creative commons B&W illustration, preferably with 4 cells, showing 1) unilateral cleft lip 2) bilateral cleft lip 3) unilateral CLP 4) bilateral CLP. Separately, one showing a "notch" in the lip. OR an 🧑‍🎨artist to draw them! #cleftpalate #cleftlipandpalate 🦋 #bskySPEECHIES