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Home - 14TH ANNUAL MEETING ON CILIA, FLAGELLA AND CENTROSOMES 14TH ANNUAL MEETING ON CILIA, FLAGELLA AND CENTROSOMES

Registrations for our 2026 meeting are now open !
Our 14th meeting on #cilia, #flagella, #centrosome and #ciliopathies to be held September 21-23, 2026, Aussois, France. Visit our website below for program, information, and registration...

www.cfc2026.conferences-pasteur.org/home

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#aiimages #iconoplasm #AIArt #AIArtist #AIArtwork #GenArt #DigitalArt #AIArtGallery #AIGeneratedArt #AIArtCommunity #monster #horrorart #creativeai #synthart #lovecraft #flagella #hydra #zoo

Saturday at the Exo-Zoo

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Hello everyone, we had a great meeting yesterday @institutimagine.bsky.social , thanks again to all the speakers for their very interesting talks on primary and motile #cilia #flagella #ciliopathies! Next one is organized by Caroline Brun, Marine Laporte, Véronique Morel in Aussois in September!

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Our next afternoon meeting is organized by @alexbnmrh.bsky.social on Wednesday March 18 @institutimagine.bsky.social ! Happy to see you soon there...
#cilia #ciliopathies #flagella

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Bacteria use wrapping flagella to tunnel through microscopic passages, research reveals Researchers have discovered how bacteria break through spaces barely larger than themselves, by wrapping their flagella around their bodies and moving forward. Using a microfluidic device that mimics…

#Bacteria use wrapping #flagella to tunnel through microscopic passages ...

| #microbes | #Caballeronia | #microbes | Via @sciencex.bsky.social

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Same moves, different terrain: How bacteria navigate complex environments without changing their playbook Just like every other creature, bacteria have evolved creative ways of getting around. Sometimes this is easy, like swimming in open water, but navigating more confined spaces poses different…

How #bacteria navigate complex environments without changing their playbook ...

| #Salmonella | #Ecoli | #flagella | #tumble | Via @sciencex.bsky.social

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Amazing to hold @lottepedersen.bsky.social & my @jcellsci.bsky.social Special Issue on #Cilia and #Flagella in all its glossy glory & muscle-engaging brain-boosting weight! So much fabulous content from the community! Fab cover @centriolelab.bsky.social 🥰🥰 journals.biologists.com/jcs/pages/ci...

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A tug-of-war explains a decades-old question about how bacteria swim Scientists have uncovered a new explanation for how swimming bacteria change direction, providing fresh insight into one of biology's most intensively studied molecular machines.

A tug-of-war explains a decades-old question about how #bacteria swim ...

| #microbes | #flagella | #chemotaxis | By @simonsfoundation.org via @sciencex.bsky.social

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New View of Cholera ‘Tail’ Could Inform Treatment Researchers took a detailed image of the cholera bacteria’s flagella, which could explain how they move so quickly and offer new routes for treatment.

m.yale.edu/dddn @yaleschoolofmed.bsky.social @natmicrobiol.nature.com #flagella #Vibriocholerae

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Scientists Discover a Surprisingly Simple New Way Microbes Travel Without Flagella Two new studies uncover unexpected ways that microbes move, offering insights that could impact our understanding of human health and disease. New research from Arizona State University has uncovered...

Scientists Discover a Surprisingly Simple New Way Microbes Travel Without Flagella #Science #Biology #Microbiology #MicrobialTravel #Flagella #ScientificDiscovery

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⭐ NAR Breakthrough! ⭐
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...

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Hello everyone, just to announce that our next afternoon symposium on #cilia #flagella and #ciliopathies will take place @institutimagine.bsky.social on Wednesday afternoon March 18 2026. Save the date!

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How life first got moving: Nature's motor from billions of years ago Research led by the University of Auckland has cast light on the evolutionary origins of one of nature's first motors, which developed 3.5 billion to 4 billion years ago to propel bacteria.

#Nature's motor from billions of years ago ...

| #evolution | #bacteria | #microbes | #propulsion | #flagellum | #flagella | Via @sciencex.bsky.social

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Bacteria use sugar-fueled currents and molecular gearboxes to move without flagella New studies from Arizona State University reveal surprising ways bacteria can move without their flagella—the slender, whip-like propellers that usually drive them forward.

#Bacteria use #sugar-fueled currents and molecular #gearboxes to move without #flagella ...

| #microbes | #infections | #propellers | #Ecoli | #Salmonella | Via @sciencex.bsky.social

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In an eight-person rowing boat, each rower contributes to movement but also has a unique role: balancing, powering, or setting the rhythm and pace. In our latest collaborative work we asked – do the eight dynein “rowers” in #cilia and #flagella operate in the same way?

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It was a great pleasure working with @cilialab.bsky.social and @seemagrewal.bsky.social plus others at @jcellsci.bsky.social on this special issue on ‘Cilia and flagella’. Lots of cool stuff on #cilia #flagella in there, enjoy!

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Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.

Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella

journals.biologists.com/jcs/issue/13...

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Great Science! Great food and great company in Oberbronn! Thank you to the organizers of the CFC meeting 2025! Thank you for all the fantastic talks & posters! + unbeatable morning runs! @club-cfc.bsky.social @bastinlab.bsky.social @alexbnmrh.bsky.social #cilia #flagella #centrosome #ciliopathies

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Overall architecture of sperm axonemal DMTs in Cfap77-KO mice. Top left:  In-cell structural determination of sperm axonemal DMTs from Cfap77-KO mice. A cryo-EM map of DMTs with an 8 nm repeat was obtained by subtomogram analysis. The lost density (yellow colour) in sperm axonemal DMTs from Cfap77-KO mice was obtained by subtracting the density map of Cfap77-KO DMTs from that of the WT DMTs (EMD-35210/35211). The transverse sectional view of DMTs and the side view of the B-tubule lumen are shown. Bottom left: The atomic model of WT DMTs (PDB: 8I7O) fitted into the density map of Cfap77-KO DMTs. The Cfap77-KO DMTs presented a loss of density corresponding to the CFAP77-CCDC105-TEX43 subcomplex near protofilaments A11 and A12. Right: OJ-focused classification performed with good DMT particles. Red arrowheads mark the sites at which protofilament contacts are weakened or lost (A10–B01 and B01–B02).

Overall architecture of sperm axonemal DMTs in Cfap77-KO mice. Top left: In-cell structural determination of sperm axonemal DMTs from Cfap77-KO mice. A cryo-EM map of DMTs with an 8 nm repeat was obtained by subtomogram analysis. The lost density (yellow colour) in sperm axonemal DMTs from Cfap77-KO mice was obtained by subtracting the density map of Cfap77-KO DMTs from that of the WT DMTs (EMD-35210/35211). The transverse sectional view of DMTs and the side view of the B-tubule lumen are shown. Bottom left: The atomic model of WT DMTs (PDB: 8I7O) fitted into the density map of Cfap77-KO DMTs. The Cfap77-KO DMTs presented a loss of density corresponding to the CFAP77-CCDC105-TEX43 subcomplex near protofilaments A11 and A12. Right: OJ-focused classification performed with good DMT particles. Red arrowheads mark the sites at which protofilament contacts are weakened or lost (A10–B01 and B01–B02).

Mammalian #cilia & #flagella depend on association of A- & B-tubules to form axonemal doublet #microtubules, but how? This study shows that CFAP77 is essential role for #axonemal connection of these tubules and crucial for #sperm motility & #fertility in mice @plosbiology.org 🧪 plos.io/4ouZ2KJ

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Overall architecture of sperm axonemal DMTs in Cfap77-KO mice. Top left:  In-cell structural determination of sperm axonemal DMTs from Cfap77-KO mice. A cryo-EM map of DMTs with an 8 nm repeat was obtained by subtomogram analysis. The lost density (yellow colour) in sperm axonemal DMTs from Cfap77-KO mice was obtained by subtracting the density map of Cfap77-KO DMTs from that of the WT DMTs (EMD-35210/35211). The transverse sectional view of DMTs and the side view of the B-tubule lumen are shown. Bottom left: The atomic model of WT DMTs (PDB: 8I7O) fitted into the density map of Cfap77-KO DMTs. The Cfap77-KO DMTs presented a loss of density corresponding to the CFAP77-CCDC105-TEX43 subcomplex near protofilaments A11 and A12. Right: OJ-focused classification performed with good DMT particles. Red arrowheads mark the sites at which protofilament contacts are weakened or lost (A10–B01 and B01–B02).

Overall architecture of sperm axonemal DMTs in Cfap77-KO mice. Top left: In-cell structural determination of sperm axonemal DMTs from Cfap77-KO mice. A cryo-EM map of DMTs with an 8 nm repeat was obtained by subtomogram analysis. The lost density (yellow colour) in sperm axonemal DMTs from Cfap77-KO mice was obtained by subtracting the density map of Cfap77-KO DMTs from that of the WT DMTs (EMD-35210/35211). The transverse sectional view of DMTs and the side view of the B-tubule lumen are shown. Bottom left: The atomic model of WT DMTs (PDB: 8I7O) fitted into the density map of Cfap77-KO DMTs. The Cfap77-KO DMTs presented a loss of density corresponding to the CFAP77-CCDC105-TEX43 subcomplex near protofilaments A11 and A12. Right: OJ-focused classification performed with good DMT particles. Red arrowheads mark the sites at which protofilament contacts are weakened or lost (A10–B01 and B01–B02).

Mammalian #cilia & #flagella depend on association of A- & B-tubules to form axonemal doublet #microtubules, but how? This study shows that CFAP77 is essential role for #axonemal connection of these tubules and crucial for #sperm motility & #fertility in mice @plosbiology.org 🧪 plos.io/4ouZ2KJ

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Overall architecture of sperm axonemal DMTs in Cfap77-KO mice. Top left:  In-cell structural determination of sperm axonemal DMTs from Cfap77-KO mice. A cryo-EM map of DMTs with an 8 nm repeat was obtained by subtomogram analysis. The lost density (yellow colour) in sperm axonemal DMTs from Cfap77-KO mice was obtained by subtracting the density map of Cfap77-KO DMTs from that of the WT DMTs (EMD-35210/35211). The transverse sectional view of DMTs and the side view of the B-tubule lumen are shown. Bottom left: The atomic model of WT DMTs (PDB: 8I7O) fitted into the density map of Cfap77-KO DMTs. The Cfap77-KO DMTs presented a loss of density corresponding to the CFAP77-CCDC105-TEX43 subcomplex near protofilaments A11 and A12. Right: OJ-focused classification performed with good DMT particles. Red arrowheads mark the sites at which protofilament contacts are weakened or lost (A10–B01 and B01–B02).

Overall architecture of sperm axonemal DMTs in Cfap77-KO mice. Top left: In-cell structural determination of sperm axonemal DMTs from Cfap77-KO mice. A cryo-EM map of DMTs with an 8 nm repeat was obtained by subtomogram analysis. The lost density (yellow colour) in sperm axonemal DMTs from Cfap77-KO mice was obtained by subtracting the density map of Cfap77-KO DMTs from that of the WT DMTs (EMD-35210/35211). The transverse sectional view of DMTs and the side view of the B-tubule lumen are shown. Bottom left: The atomic model of WT DMTs (PDB: 8I7O) fitted into the density map of Cfap77-KO DMTs. The Cfap77-KO DMTs presented a loss of density corresponding to the CFAP77-CCDC105-TEX43 subcomplex near protofilaments A11 and A12. Right: OJ-focused classification performed with good DMT particles. Red arrowheads mark the sites at which protofilament contacts are weakened or lost (A10–B01 and B01–B02).

Mammalian #cilia & #flagella depend on association of A- & B-tubules to form axonemal doublet #microtubules, but how? This study shows that CFAP77 is essential role for #axonemal connection of these tubules and crucial for #sperm motility & #fertility in mice @plosbiology.org 🧪 plos.io/4ouZ2KJ

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Intraflagellar transport selectivity occurs within the proximal portion of the trypanosome flagellum In Trypanosoma brucei, IFT trains selectively associate with specific axonemal microtubules. Using advanced microscopy, Araujo Alves et al. reveal how this

How do trypanosome IFT trains choose special tracks? Yameng Huang and Cynthia He (National University of Singapore) discuss recent advances from @bastinlab.bsky.social (rupress.org/jcb/article/...), in Spotlight: rupress.org/jcb/article/...

#Biochemistry #Organelles #Cilia #Flagella #Trypanosomes

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In situ structure of a bacterial flagellar motor at subnanometre resolution reveals adaptations for increased torque - Nature Microbiology In situ cryoEM and modelling of the Campylobacter jejuni flagellar motor characterize the periplasmic scaffold and the structural basis for increased torque generation.

In situ structure of a bacterial flagellar motor at subnanometre resolution reveals adaptations for increased torque
#microbiology #bacteria #flagella
@natmicrobiol.nature.com
www.nature.com/articles/s41...

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Intraflagellar transport selectivity occurs within the proximal portion of the #trypanosome flagellum, say Aline Araujo Alves, Philippe Bastin and colleagues @bastinlab.bsky.social @pasteur.fr: rupress.org/jcb/article/...

#Microbiology #Cilia #Trafficking #StructuralBiology #Flagella

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Rescue of bacterial motility using two- and three-species FliC chimeras | Journal of Bacteriology Flagellin is a key protein forming the filament of the bacterial flagellar motor which powers most bacterial swimming. Flagellin can have hypervariable domains which can alter motility in different en...

🚨New Paper Alert🚨Our latest paper is published now in the Journal of Bacteriology @asm.org!🦠🔬🏃

A huge thanks to all the co-authors (Matthew Baker, Divyangi Pandit, Pietro Ridone and Yoshiyuki Sowa) for all their hard work! @unswbabs.bsky.social
#flagella #chimera

journals.asm.org/doi/10.1128/...

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The nucleus is fantastic, but can it beat #cilia and #flagella 😉 here stained for tubulin (magenta) with an intraflagellar transport train (green) after #expansion microscopy and #STED or shown by classic TEM. JCS @jcellsci.bsky.social found the solution and is featuring both! 😍

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More on #cilia, #flagella & #fertility with Alyssa Long (@tamaragenes.bsky.social lab, Emory, US) on dissecting cilial vs non-cilial functions for ARL13B in rescuing #mouse mutant #ciliopathy phenotypes in vivo- great questions & discussions live! ICYMI: doi.org/10.1101/2025... #UKCilia2025 4/7

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Meeting Cils, Flagelles et Centrosomes à 67-Oberbronn Cette année, le meeting Cils, Flagelles et Centrosomes aura lieu du 13 au 15 octobre. This year, the Cilia, Flagella and Centrosome Meeting will take place from October 13th to 15th.

First announcement for the 2025 meeting of the #cilia, #flagella and #centrosome club which will be held from October 13 to 15, in Oberbronn, Alsace, eastern France.

gmgm.unistra.fr/en/news/meet...

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Last few days to submit your research on #cilia and #flagella to our upcoming special issue, coordinated by Guest Editors Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social.
journals.biologists.com/jcs/pages/ci...

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Special Issue Cilia and Flagella: from Basic Biology to Disease 
Guest Editors: Plesantine Mill and Lotte Pedersen
Submission deadline: 1 March 2025
Journal of Cell Science logo
Call for papers

Special Issue Cilia and Flagella: from Basic Biology to Disease Guest Editors: Plesantine Mill and Lotte Pedersen Submission deadline: 1 March 2025 Journal of Cell Science logo Call for papers

Only a few days left to submit your latest research to @jcellsci.bsky.social‬ 's upcoming Special Issue on #cilia and #flagella, coordinated by Pleasantine Mill @cilialab.bsky.social & Lotte Pedersen @lottepedersen.bsky.social .
📆 Deadline: 1 March
https://bit.ly/4ed1Re7

#CallforPapers #CellBio

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