According to new research, the G3BP1 protein helps cancer cells evade chemotherapy. Targeting this protein could enhance treatment efficacy！👇
#G3BP1 #cancer #bone
@brjournal.bsky.social
www.nature.com/articles/s41...

Interested in joining the group as a motivated Master's or PhD student?
Reach out to Dr. Nina Ripin at nina.ripin(at)ur.de.

More news and job ads coming soon – stay tuned! 🚀

#RNA #Condensates #StressGranules #G3BP1

🧠 How do bunyaviruses evade host defenses?
Gerlach’s team (Polish Academy of Sciences), with ISIDORe & EMBL, revealed how viral proteins mimic SG partners to hijack G3BP1—disrupting stress granules.


🔬 Crystal structures + cell imaging
📢 To be shared at EMBO/NSV 2025


#ISIDORe #G3BP1 #Virology

#alternativetranslation #cancer #scc #ribosomequalitycontrol #ribosome #skin #usp10 #g3bp1 #rnf10 #ubiquitin #turboID #silac #massspectrometry #proteomics #riboseq #eIF2A #translation #mRNA

C9orf72-linked arginine-rich dipeptide repeats aggravate pathological phase separation of G3BP1 | PNAS The toxic effects of C9orf72-derived arginine-rich dipeptide repeats (R-DPRs) on cellular stress granules in amyotrophic lateral sclerosis (ALS) an...

Our latest #C9orf72 ALS paper is out demonstrating biomolecular #condensation of #G3BP1 driven by R-DPRs:
📰 C9orf72-linked arginine-rich dipeptide repeats aggravate pathological phase separation of G3BP1 🔬
www.pnas.org/doi/10.1073/...

#neurodegeneration #MND #ALS #endALS #FTD #LLPS