🤝 New partnership: AsedaSciences + Xenometrix

We’re integrating the Ames mutagenicity test into the 3RnD® platform—modernizing a regulatory-trusted assay to support earlier, NAM-based genotox decisions at scale.

Learn more: lnkd.in/e7DwHEBF

@scicrunch.bsky.social #Biotech #Genotoxicity #NAMs

🤝 New partnership: AsedaSciences® + GenEvolutioN®

We’re integrating best-in-class Micronucleus genotoxicity screening into the 3RnD® platform—enabling earlier, data-driven genotox assessment and broader adoption of NAMs.

Learn more: lnkd.in/e_8dxPcG

@scicrunch.bsky.social #Biotech #Genotoxicity

Potassium Bromate: The Hidden Carcinogen in Your Daily Bread? In today's episode we're uncovering the dark side of common baked goods by examining Potassium Bromate, a powerful oxidizing agent used to strengthen dough. Despite being linked to kidney cancer, thyroid disease, and DNA damage, this additive remains legal in the U.S. while being banned in Europe, Canada, and China. We explore 50 years of research highlighting its toxicity, the recent ban in California, and why it was "grandfathered" into our food supply.  References: https://usrtk.org/chemicals/potassium-bromate/ Support Foodnourish Deep Dives Become a supporter for just 2€ per month. This removes any advertisements and help us continue bringing more interesting topics and confronting mainstream narrative on health. Link to support: https://www.spreaker.com/podcast/foodnourish-deep-dives--6602003/support

📣 New Podcast! "Potassium Bromate: The Hidden Carcinogen in Your Daily Bread?" on @Spreaker #additives #baking #bread #bromate #california #cancer #carcinogen #chemicals #fda #flour #genotoxicity #health #kidney #nutrition #potassium #regulation #safety #thyroid #toxicology #wellness

Beyond the Sweetness: Uncovering Sucralose Health Risks In today's episode we're exposing the hidden Sucralose Health Risks backed by emerging science. Originally discovered during research for a new insecticide, sucralose is now found in over 6,000 food products. We dive into how this zero-calorie sweetener is linked to leukemia, DNA damage, and metabolic dysfunction. We also examine evidence showing it may actually trigger weight gain and insulin resistance rather than helping with weight loss. Join us as we challenge the mainstream narrative and uncover the biological impact of the world's most popular artificial sweetener. References: https://usrtk.org/sweeteners/sucralose-health-risks/ ➡️ Become a supporter for just 2€ per month. This removes any advertisements and help us continue bringing more interesting topics and confronting mainstream narrative on health. Link to support: https://www.spreaker.com/podcast/foodnourish-deep-dives--6602003/support

📣 New Podcast! "Beyond the Sweetness: Uncovering Sucralose Health Risks" on @Spreaker #bioaccumulation #diabetes #diet #dna #genotoxicity #gut #health #inflammation #insulin #leukemia #metabolism #microbiome #nutrition #obesity #risks #science #splenda #sucralose #sweetener #toxicity

Neonicotinoid Insecticides: The Unseen Threat to Male Fertility In today's episode we're examining the hidden health risks associated with Neonicotinoid Insecticides, the world's most widely used class of pesticides. Neonics are used extensively in agriculture, leading to inevitable occupational and environmental contamination, including detectable levels in food and water. Since these chemicals are applied systemically, they are absorbed throughout the plant tissues, making them very difficult—if not impossible—to remove completely by washing produce. Recent systematic reviews analyzing 21 animal studies consistently show that neonic exposure negatively impacts male reproductive health. Specifically, studies reveal compromised sperm quality (count, motility, viability, morphology), damage to testicular tissue, hormonal disruption (lowered serum testosterone), and severe oxidative stress. These consistent findings, derived primarily from rodent models, constitute a clear and urgent public health concern, emphasizing the critical need for dedicated human epidemiological studies. Resources for this episode:  - https://pubmed.ncbi.nlm.nih.gov/41016496/ - https://ejchem.journals.ekb.eg/article_222251.html - https://pmc.ncbi.nlm.nih.gov/articles/PMC11329541/

📣 New Podcast! "Neonicotinoid Insecticides: The Unseen Threat to Male Fertility" on @Spreaker #clothianidin #dna #edc #exposure #fertility #genotoxicity #hormones #imidacloprid #insecticides #male #neonicotinoids #oxidative #pesticides #reproductive #sperm #stress #testosterone #thiacloprid

Live picture from the meeting room - FSA’s Stakeholder Genotoxicity Workshop

Live picture from the meeting room - FSA’s Stakeholder Genotoxicity Workshop

🔬 Today & tomorrow, experts meet in Brussels for EFSA’s Stakeholder Genotoxicity Workshop: discussing the revision of EFSA’s genotoxicity guidance and exploring new scientific approaches for future risk assessment.

👉 link.europa.eu/qdqHmq

#Genotoxicity #FoodSafety #Science

Using #KidneyOrganoids, this #STTT study shows that AAV transduction during #GeneTherapy promotes #Nephrotoxicity by inducing #Genotoxicity and IL-1β secretion, which activates the canonical NFκB pathway. #medsky @harvardmed.bsky.social

#OpenAccess: doi.org/10.1038/s413...

“Graphic announcing a workshop titled ‘EFSA’s Genotoxicity Guidance Revision’. The design features a large yellow semi-circle on a dark blue background, with the EFSA logo in the lower right corner.”

📢 Join our Stakeholder Workshop on the Genotoxicity Guidance Revision

🗓️ 3–4 Nov 2025 | Brussels

Discuss with experts the latest on NAMs, mixtures, and quantitative genotoxicity assessment shaping future guidance for food and feed safety.

📝 Register by 20 Oct: link.europa.eu/qdqHmq

#Genotoxicity

PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Expanding the toolbox for #GeneTagging: Higher antitumor efficacy & lower #GenoToxicity of Cas9 nickase–based adenine-base editing vs to nuclease-active Cas9 opens avenues to improve #CARTcelltherapy doi.org/10.1073/pnas... @carlhjune #TranslationalScience

Neonicotinoid Exposure Threatens Fish Health, Highlighting Cascading Effects to Humans as Consumers - Beyond Pesticides Daily News Blog Exposure to thiamethoxam, a neonicotinoid insecticide, causes a myriad of health effects in fish that can then impact humans who consume them.

Subacute and chronic exposure to #neonic #insecticide #thiamethoxam is newly linked to #genotoxicity, oxidative stress, and changes in the tissue structure of Nile tilapia, with "the severity of the damage increasing with the concentration of the #pesticide." 🐟 #foodweb ➡️ Blog: ow.ly/p6wN50VPko0

A Comparative Study on Genotoxic and Oxidative DNA Damage in Oral Epithelial Cells of COVID-19 Suspected Patients Introduction The SARS-CoV-2 virus causes COVID-19 by chiefly infecting the nasal and oral mucosal cavities, where its spike proteins bind to angiotensin-converting enzyme II (ACE2) receptors on epith...

This study aimed to assess #covid related #genotoxicity in #buccalmucosalcells through micronuclei counts & 8-Oxo-2'-deoxyguanosine (8-OHdG) expression…

www.cureus.com/articles/344...

Transcriptomic signatures reveal genotoxin exposure in blood cells, offering insights for toxic exposure assessment:
doi.org/10.3390/ijms...
#Genotoxicity #Health #Science #HBM4EU

Pesticide-Contaminated Algae Found to Jeopardize Ecosystems and Human Well-Being [Study] - Beyond Pesticides Daily News Blog Algae exposed to pesticides jeopardize environmental integrity, ecological communities, and human well-being.

The disruption of #algal communities with #pesticides is found to have a devastating effect on #aquatic #foodweb #health in lit review, "causing tissue injury, developmental delay, #genotoxicity, procreative disruption, and tissue #biomagnification." Blog:

ow.ly/2lr950Sh81L

Wide Range of Harmful Effects of Pesticides Documented in Literature Review - Beyond Pesticides Daily News Blog In a study from earlier this year, scientists examined research regarding the use of harmful pesticides and adverse effects including genotoxicity.

Researchers from @ChitkaraU & @Philadelphia_Jo analyzed 150+ articles regarding #pesticide use & their #adverse effects on #health, noting that "the risk of DNA damage surges with increased #genotoxicity in people exposed to #pesticides." Blog:

ow.ly/P5f950RofEz