Zelig Eshhar: The Pioneer Who Re-Engineered the T-Cells and Brought CAR-T into the World

dl.begellhouse.com/journals/439...

#CARTCellTherapy #CancerImmunotherapy #TcellEngineering #CRO

Recovery after CAR T-cell therapy continues beyond treatment.

Learn about long-term side effects, risk factors, and how to monitor and manage your health moving forward.

🗓 May 4
🕝 2:30 p.m. ET

Register: bmtinfonet.org/registration...

#CARTCellTherapy #BMTInfoNet #CancerSurvivorship

Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer - Nature Biomedical Engineering A pan-haematologic cancer approach, involving analysis of data from 256 patients across 5 cancer types and 13 clinical trials, revealed predictive biomarkers for understanding the response or non-resp...

Leveraging #ComputationalBiology at scale to individualize #Immunotherapy: www.nature.com/articles/s41... @JoeFraietta @carlhjune #CARTcelltherapy #CellTherapy #CARTCell #TranslationalScience

Cancer treatment: Optimization of CAR T-cell therapy – BioNews Central Researchers improve the efficacy of CAR T-cell therapy in solid tumors by modifying T cells to make them resistant to local inhibition within the tumor microenvironment. ...

Researchers improve the efficacy of #CARTCellTherapy in #SolidTumors by modifying #TCells to make them resistant to local inhibition within the #TumorMicroenvironment.
#CancerTreatment

How do teams assess readiness for transplant or CAR T in older adults?

Episode 6 of Thrive! explores frailty and resilience with guidance from Dr. Amelia Langston.

Apple: podcasts.apple.com/us/podcast/t...
YouTube: youtu.be/sSlvjW1fW1Q

#StemCellTransplant #CARTCellTherapy

🚪 Doors are open 🎬 The 8th European CAR T-cell Meeting starts with the Opening Session at 12:30 CET.

🏛️ See you at the event venue 📍 Palma Convention Centre or 💻 online in the virtual meeting platform. 🙂

We hope you enjoy #CART26! 👏

#CARTcelltherapy #cellulartherapy

Scientific poster explaning the findings - CONCLUSION For patients and caregivers, travel time and cost , difficulties with care coordination, securing a 24/7 caregiver, and the perceived risk of side effects are the most significant barriers to CAR T. • Having to travel long distances to academic cancer centers away from patients’ primary care sites for CAR T cell therapy compounded the psychosocial and financial burden associated with receiving CAR T for patients and caregivers. • The time, financial, and social toxicity associated with CAR T cell therapy impacts patients, caregivers, families, and communities. • CAR T should be made available at more care sites and supportive resources should be made more widely available to reduce the financial, logistic, and psychosocial burden of CAR T and improve access to this innovative therapy

Why do 80% of eligible patients miss out on life-saving #CARTCellTherapy?

www.CancerSupportCommunty.org's research reveals real barriers—financial toxicity, travel burden, caregiver strain—that keep patients from accessing CAR T.
#Tandem26, ⏰ 6:30-8p, 📅 Th, 2/5

#CART #HealthEquity
bit.ly/3LRWDwh

📣 Late-breaking abstract submission for #CART26 is now open. 📰 Take advantage of this second chance to highlight the latest developments in your research. 🔬
Learn more: 🔗 www.ebmt.org/events/ebmt-eha-8th-euro...

#abstractsubmission #CellTherapy #CARTcelltherapy

Spain CAR T Cell Therapy Market Size, Share, Forecast 2035 Spain Car T Cell Therapy Market share register 221.71 USD Million in 2024, projected to grow 15.48 % CAGR to reach USD Million 1079.98 during the forecast period 2025 - 2035.

🧬 Spain’s CAR-T cell therapy market is advancing personalized cancer treatment. www.marketresearchfuture.com/reports/spai... #CARTCellTherapy #Oncology 🇪🇸

CAR-T Cell Therapy: Revolutionizing Cancer Treatment and its Implications for Future Therapeutic Strategies: A Review - Premier Science Palak Parmar, Sangeeta Dwivedi , Vikas K. Jain, Hariom Carpenter and Gajanand DarwhekarDepartment of Pharmacology, Acropolis Institute of Pharmaceutical

doi.org/10.70389/PJS...

#carTcelltherapy #cancertreatment #cancer #oncology

CAR T-cell therapy promotes rejuvenation of intestinal epithelium – BioNews Central Biologists have developed a new method using CAR T-cell therapy to stimulate growth and repair of the intestinal epithelium, potentially advancing treatments for age-related gut disorders. ...

Biologists have developed a new method using #CARTCellTherapy to stimulate growth and #repair of the #IntestinalEpithelium, potentially advancing treatments for #AgeRelated #GutDisorders.
#Aging #Senescence #LeakyGut #LeakyGutRepair #Immunotherapy

A routine blood test could help predict who benefits most from CAR T-cell therapy – BioNews Central Measuring a patient’s absolute lymphocyte count can help predict their response to CAR T-cell therapy for non-Hodgkin lymphoma, providing a practical tool to guide treatment decisions. ...

Measuring a patient’s absolute #LymphocyteCount can help predict their response to #CARTcelltherapy for #NonHodgkinLymphoma, providing a practical tool to guide #TreatmentDecisions.
#TherapyResponse #ClinicalOutcomes

Fred Hutch at #ASH25: Catch Dr. Emily Liang present "High-dose anakinra to treat refractory immune effector cell-associated neurotoxicity syndrome in #CARTcelltherapy recipients" 👉 https://bit.ly/4rCgeQL

For many blood cancer patients, CAR T-cell therapy is game-changing CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has been extremely effective against lymphoma, multiple myeloma and certain leukemias. Mazyar Shadman, MD...

Ahead of #ASH25, we sat down with Dr. Mazyar Shadman, medical director of cellular #immunotherapy at Fred Hutch, to discuss the barriers to accessing #CARTcelltherapy and what patients and providers should know about this treatment: https://bit.ly/3KqbNIk

A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma Rade et al. present a longitudinal single-cell atlas of BCMA CAR-T therapy in multiple myeloma, revealing that cilta-cel drives potent CD4⁺ cytotoxic responses and superior outcomes. Their findings id...

A longitudinal study led by Dr. Maximilian Merz sheds new light on why cilta-cel yielded better response rates compared to ide-cel for those with relapsed/refractory #multiplemyeloma. @mskcancercenter.bsky.social #mmsm @szusmani.bsky.social #CARTcelltherapy

A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors - Nature Biotechnology The interactions of CAR-T cells and solid tumors are modeled on a chip.

Advancing chimeric antigen receptor #CARTcellTherapy for #SolidMalignancies through tumor-on-a-chip technology www.nature.com/articles/s41... #OrganTumorOnAChip #Cancer #CellTherapy #CARTCell #ImmunoTherapy #Oncology #TranslationalScience

An overview of #CARTcelltherapy, examining applications in #HematologicMalignancies and #SolidTumors, while highlighting ongoing trials and future directions for effective CAR-T therapies in #AML. @idibaps.bsky.social #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

#CellandGeneTherapy #CGT #Uniphar #personalisedmedicine #Celltherapy #CARTcelltherapy #Genetherapy #CGTlandscape #CGTpipeline #genetherapytrials #Expandedaccess #NamedPatientSupply #FreeofChargeaccess #FOCaccess #MAPs #EAPs #realworldevidencegeneration #marketreadiness
zurl.co/2pdyj

As we still celebrate the Laureates 2025, let’s take a closer look at the Laureates’ groundbreaking research on CAR-T cell therapy – and what makes it so transformative for the future of medicine! #CancerResearch #MedicalInnovation #cartcelltherapy #cancer #cancercure

As we still celebrate the Laureates 2025, let’s take a closer look at the Laureates’ groundbreaking research on CAR-T cell therapy – and what makes it so transformative for the future of medicine! #CancerResearch #MedicalInnovation #cartcelltherapy #cancer #cancercure

As we still celebrate the Laureates 2025, let’s take a closer look at the Laureates’ groundbreaking research on CAR-T cell therapy – and what makes it so transformative for the future of medicine! #CancerResearch #MedicalInnovation #cartcelltherapy #cancer #cancercure

As we still celebrate the Laureates 2025, let’s take a closer look at the Laureates’ groundbreaking research on CAR-T cell therapy – and what makes it so transformative for the future of medicine! #CancerResearch #MedicalInnovation #cartcelltherapy #cancer #cancercure

As we still celebrate the Laureates 2025, let’s take a closer look at the Laureates’ groundbreaking research on CAR-T cell therapy – and what makes it so transformative for the future of medicine!

#CancerResearch #MedicalInnovation #cartcelltherapy #cancer #cancercure

Turning All Cancers Into Curable Diseases - Dr. Karen Knudsen MBA PhD - CEO, Parker Institute for Cancer Immunotherapy, joins me on Progress, Potential, And Possibilities #ProstateCancer #CARTCellTherapy #CheckpointInhibitors #TumorAntigens #TumorMicroenvironment www.youtube.com/watch?v=cyrO...

Kraft Family Blood Donor Center

On Apheresis Awareness Day, the Kraft Family Blood Donor Center honors donors, apheresis practitioners & patients for whom T-cells are removed, modified in the lab and infused back so they are stronger and ready to attack cancer head-on. #CARTCellTherapy #TCellCollection @danafarber.bsky.social

Jan Janisch-Hanzlik had been having strange symptoms for several years. But it was a sensation that started in her toes and crept up her right side that really concerned her.

buff.ly/gBfzHzM

#MED #NebraskaMedicine #MultipleSclerosis #CARTCellTherapy

REVIEW: Aging and immunity: the age-old tango
by Fernández Maestre et al. @corina-amor.bsky.social‬ @cshlaboratory.bsky.social‬
➡️ https://tinyurl.com/gd352644

#aging #senescence #cancer #immuneregulation #antiaging #immunotherapy #CancerImmunotherapy #Inflammaging #CARTCellTherapy #CART

This review outlines #CARTcelltherapy in hematologic & solid #tumors, highlights challenges in #AML therapy, explores ongoing #ClinicalTrials, & discusses strategies to optimize AML therapy. #medsky @idibaps.bsky.social

Latest in #STTT #OpenAccess: www.nature.com/articles/s41...

CAR T-Cell Therapy: A New Frontier in Cancer Immunotherapy - OncoDaily Explore how CAR T-cell therapy works, its approved uses, challenges in solid tumors, and future innovations in precision immunotherapy.

CAR T-Cell Therapy: A New Frontier in Cancer Immunotherapy

oncodaily.com/oncolibrary/...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #CARTCellTherapy #CART #Immunotherapy #IO

In vivo screening reveals cell-intrinsic mediators of solid tumor resistance to CAR T cell-therapy
Chen, E., Doherty, S. et al.
Paper
Details
#CARTCellTherapy #SolidTumorResistance #InVivoScreening

CARTITUDE-1: Single #CARTCellTherapy infusion shows potential for cure in relapsed/refractory #MultipleMyeloma
📊 5-year PFS in 33% of patients; MRD & PET-negative in subset
📰 July cover story of The ASCO Post
👨‍⚕️ Peter M. Voorhees, MD
🔗 ascopost.com/issues/july-...

R.I.P., Zelig #Eshhar [°Feb. 25, 1941 – July 3, 2025]🕯️🫡🌹

#Immunotherapy #cancer #Tcells #CART #CARTcellTherapy #IchilovHospital #DepartmentofImmunology #WeizmannInstituteofScience #BarujBenacerraf #GideonGross #StevenRosenberg #ScottGottlieb #NomiFriedlander #ZeligLipka #ZeligEshhar

In vivo CAR T cell generation to treat cancer and autoimmune disease Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity f...

Broadening clinical utility of #CARTcelltherapy through in vivo engineering targeted lipid nanoparticles (tLNPs) for messenger RNA delivery to specific T cell subsets doi.org/10.1126/scie... @carlhjune @Haig_Ag #CellTherapy #CARTCell #TranslationalScience

Key takeaways from world’s largest cancer conference in Chicago Experts announce findings on immunotherapy, a breast cancer breakthrough and the value of exercise

CAR T-Cell Therapy is something new for #glioblastoma.
#CARTCellTherapy #Cancer